braincancerlab.bsky.social @braincancerlab.bsky.social · 03/11/2025Excited to see the updated results from INDIGO confirming sustained benefit of mIDH inhibition for 1st line treatment in patients with G2 gliomas. Reduced seizure frequency aligns with our findings that mIDH inhibition modulates the glioma electrical microenvironment! 👇 121
Reposted by @braincancerlab.bsky.socialWEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · 22/08/2025A landmark research milestone, from a brilliant collaborative team, published in @natmed.nature.com 🔗 www.nature.com/articles/s41... @sarahannbest.bsky.social @saskiafreytag.bsky.social tag.bsky.social @jimwhittle.bsky.socialnature.comPerioperative IDH inhibition in treatment-naive IDH-mutant glioma: a pilot trial - Nature MedicineThis pilot trial showed that perioperative treatment with the isocitrate dehydrogenase (IDH) inhibitor safusidenib of patients with low-grade IDH-mutant glioma, with craniotomy and lumbar puncture bef... 285
Reposted by @braincancerlab.bsky.socialSarah Best @sarahannbest.bsky.social · 22/08/2025So incredibly proud of my team and our collaborators. What a fantastic step forward for brain cancer clinical trials and mIDH inhibitors @braincancerlab @jimwhittle.bsky.social @saskiafreytag.bsky.social @wehi-research.bsky.social www.nature.com/articles/s41...nature.comPerioperative IDH inhibition in treatment-naive IDH-mutant glioma: a pilot trial - Nature MedicineThis pilot trial showed that perioperative treatment with the isocitrate dehydrogenase (IDH) inhibitor safusidenib of patients with low-grade IDH-mutant glioma, with craniotomy and lumbar puncture bef... 0201
Reposted by @braincancerlab.bsky.socialWEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · 22/08/2025Researchers from WEHI, the Royal Melbourne Hospital & @petermaccc.bsky.social have achieved a brain cancer clinical trial world-first, providing hope to patients with low-grade gliomas. 🔗 www.wehi.edu.au/news/world-f... 1126
braincancerlab.bsky.social @braincancerlab.bsky.social · 22/08/2025A central question in neuro-oncology is whether therapies penetrate the tumour and exert a biological effect. @jimwhittle.bsky.social and colleagues developed BrainPOP, a perioperative clinical trial platform and our lab had the pleasure of leading the translational research. 1/8 100