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braincancerlab.bsky.social

@braincancerlab.bsky.social
135 followers 456 following 16 posts

Interdisciplinary brain cancer lab headed by @sarahannbest.bsky.social, @SaskiaFreytag.bsky.social, and @jimwhittle.bsky.social studying brain cancer at the @WEHI-research.bsky.social .

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braincancerlab.bsky.social @braincancerlab.bsky.social · 03/11/2025
Excited to see the updated results from INDIGO confirming sustained benefit of mIDH inhibition for 1st line treatment in patients with G2 gliomas. Reduced seizure frequency aligns with our findings that mIDH inhibition modulates the glioma electrical microenvironment! 👇
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WEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · 22/08/2025
A landmark research milestone, from a brilliant collaborative team, published in @natmed.nature.com 🔗 www.nature.com/articles/s41... @sarahannbest.bsky.social @saskiafreytag.bsky.social tag.bsky.social @jimwhittle.bsky.social
nature.com
Perioperative IDH inhibition in treatment-naive IDH-mutant glioma: a pilot trial - Nature Medicine
This pilot trial showed that perioperative treatment with the isocitrate dehydrogenase (IDH) inhibitor safusidenib of patients with low-grade IDH-mutant glioma, with craniotomy and lumbar puncture bef...
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Sarah Best @sarahannbest.bsky.social · 22/08/2025
So incredibly proud of my team and our collaborators. What a fantastic step forward for brain cancer clinical trials and mIDH inhibitors @braincancerlab @jimwhittle.bsky.social @saskiafreytag.bsky.social @wehi-research.bsky.social www.nature.com/articles/s41...
nature.com
Perioperative IDH inhibition in treatment-naive IDH-mutant glioma: a pilot trial - Nature Medicine
This pilot trial showed that perioperative treatment with the isocitrate dehydrogenase (IDH) inhibitor safusidenib of patients with low-grade IDH-mutant glioma, with craniotomy and lumbar puncture bef...
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Reposted by @braincancerlab.bsky.social
WEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · 22/08/2025
Researchers from WEHI, the Royal Melbourne Hospital & @petermaccc.bsky.social have achieved a brain cancer clinical trial world-first, providing hope to patients with low-grade gliomas. 🔗 www.wehi.edu.au/news/world-f...
The BrainPOP research team (left to right): Professor Kate Drummond, Dr Jim Whittle, Dr Saskia Freytag, Dr Sarah Best
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braincancerlab.bsky.social @braincancerlab.bsky.social · 22/08/2025
A central question in neuro-oncology is whether therapies penetrate the tumour and exert a biological effect. @jimwhittle.bsky.social and colleagues developed BrainPOP, a perioperative clinical trial platform and our lab had the pleasure of leading the translational research. 1/8
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