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Saskia Freytag

@saskiafreytag.bsky.social
854 followers 654 following 3 posts

Lab Head at the WEHI and the Brain Cancer Center by CB4BC. BioinfoMagician using computational biology, spatial and single cell omics so that one day no lives will be lost to brain cancer.

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Reposted by Saskia Freytag
WEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · 22/08/2025
Researchers from WEHI, the Royal Melbourne Hospital & @petermaccc.bsky.social have achieved a brain cancer clinical trial world-first, providing hope to patients with low-grade gliomas. 🔗 www.wehi.edu.au/news/world-f...
The BrainPOP research team (left to right): Professor Kate Drummond, Dr Jim Whittle, Dr Saskia Freytag, Dr Sarah Best
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Reposted by Saskia Freytag
WEHI (The Walter and Eliza Hall Institute of Medical Research) @wehi-research.bsky.social · 22/08/2025
A landmark research milestone, from a brilliant collaborative team, published in @natmed.nature.com 🔗 www.nature.com/articles/s41... @sarahannbest.bsky.social @saskiafreytag.bsky.social tag.bsky.social @jimwhittle.bsky.social
nature.com
Perioperative IDH inhibition in treatment-naive IDH-mutant glioma: a pilot trial - Nature Medicine
This pilot trial showed that perioperative treatment with the isocitrate dehydrogenase (IDH) inhibitor safusidenib of patients with low-grade IDH-mutant glioma, with craniotomy and lumbar puncture bef...
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Reposted by Saskia Freytag
Steven Sloan @sloanlab.bsky.social · 08/01/2025
First 🦋 post! Very excited to share our lab's latest work exploring the shared and divergent aspects of human astrocyte development and glioblastoma. This effort spans many fields from developmental #glial biology to #stem cells and #tumor biology. rdcu.be/d5ADz A 🧵
rdcu.be
Mapping the developmental trajectory of human astrocytes reveals divergence in glioblastoma
Nature Cell Biology - Sojka et al. analyse the transcriptomic and epigenomic landscape of human astrocyte maturation and identify an epigenetically regulated intermediate state associated with...
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Reposted by Saskia Freytag
Nature Reviews Neurology @natrevneurol.nature.com · 17/01/2025
Brain-wide neuronal circuit connectome of human glioblastoma www.nature.com/articles/s41...
nature.com
Brain-wide neuronal circuit connectome of human glioblastoma - Nature
Nature - Brain-wide neuronal circuit connectome of human glioblastoma
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Saskia Freytag @saskiafreytag.bsky.social · 14/01/2025
New review article from the lab discusses everything GBM tumor microenvironment: tech (spatial transcriptomic, metabolomics and proteomics), biology and implications for the clinic. @jimwhittle.bsky.social @sarahbest.bsky.social www.sciencedirect.com/science/arti...
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Saskia Freytag @saskiafreytag.bsky.social · 14/01/2025
New work from the lab on comparing patient-derived GBM organoids & spheroids. TLRD: Surprisingly very similar across genetic, transcriptomics and epigenetic levels!
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Saskia Freytag @saskiafreytag.bsky.social · 20/11/2024
Beautiful collaboration! Congratulations.
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