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Bradley Harris

@bradleyomics.bsky.social
93 followers 124 following 19 posts

Postdoc @sangerinstitute.bsky.social | Lover of all things single-cell ‘omic, common complex disease and genetics. Anderson lab - andersonlab.info

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Reposted by Bradley Harris
Wellcome Sanger Institute @sangerinstitute.bsky.social · 27/08/2025
Scientists have uncovered hidden genetic drivers of conditions like IBD by stimulating immune cells. 🔬 The findings have resulted in a dataset called MacroMap, which offers insight into why some people are vulnerable to certain conditions. sanger.ac.uk/news_item/ac...
sanger.ac.uk
Activated immune cells reveal hidden drivers of autoimmune diseases
A new resource, MacroMap, provides a rich dataset that researchers can use to explore genetic mechanisms behind complex diseases.
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Bradley Harris @bradleyomics.bsky.social · 08/07/2025
Delighted to share the first preprint of my postdoc in the @carlanderson.bsky.social lab www.medrxiv.org/content/10.1...! 🚨 A super exciting study I co-led with the very talented @tobioinformatics.bsky.social . Stay tuned to see what we learned about genetic susceptibility to complex disease. 🧬🧵 1/
medrxiv.org
Cell-type-resolved genetic regulatory variation shapes inflammatory bowel disease risk
Most genetic variants associated with complex diseases lie in non-coding regions, complicating efforts to identify effector genes and relevant cell types. Here, we map cis-eQTLs across 2.2 million sin...
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Reposted by Bradley Harris
Open Targets @opentargets.org · 26/06/2025
Preprint out today! A team led by @tobioinformatics.bsky.social and Bradley Harris in @carlanderson.bsky.social ‘s lab has created the largest single-cell atlas of IBD tissues to date www.medrxiv.org/content/10.1...
UMAP of the 9 populations and 86 cell types identified after quality control and clustering
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