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Carl Anderson

@carlanderson.bsky.social
675 followers 281 following 13 posts

Head of Human Genetics & Senior Group Leader @ Wellcome Sanger Institute. Statistical geneticist working on complex diseases #ibd #firstgen.

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Carl Anderson @carlanderson.bsky.social · 13/07/2025
Turns out Richard Ashcroft had it all wrong. The drugs really do work. #sinner #swiatek #wimbledon.
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Carl Anderson @carlanderson.bsky.social · 05/06/2025
Way to go, Martin! So wonderful to see this published. You really stuck at it. An important paper.
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Carl Anderson @carlanderson.bsky.social · 05/06/2025
The latest preprint from our lab, led by the amazingly talented Lucia Ramirez Navarro. Do circulating immune cells capture the transcriptomic signatures of their counterparts in the inflamed gut? No, except for a rare population of T cells expressing tissue residency markers.
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Reposted by Carl Anderson
Lucia Ramirez-Navarro @luciaramirez.bsky.social · 04/06/2025
🚨 SUPER EXCITED to share our new preprint on the mucosal and circulatory immune landscape of Crohn’s disease! 🩸 Blood is commonly used in biomarker discovery and drug development, but how well does it reflect what's actually happening in the gut? 👀 🧵 1/10 🔗 www.medrxiv.org/content/10.1...
medrxiv.org
Tissue-specific and circulatory immune signatures of mucosal inflammation in Crohn's disease
Crohn's disease (CD) is a heterogeneous disease characterized by chronic inflammation of the gastrointestinal tract driven by an aberrant immune response. To understand the immune mechanisms underlyin...
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Carl Anderson @carlanderson.bsky.social · 01/01/2025
Well, I can’t say that I’m overly disappointed to see the back of 24. But I’m very excited to see what 25 brings. I sense it will be an exciting one. Hoping that the world ends it in a better place than it begins.
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Carl Anderson @carlanderson.bsky.social · 13/12/2024
Well, today was absolutely awesome! So much for Friday 13th being unlucky.
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Carl Anderson @carlanderson.bsky.social · 22/11/2024
Massive congratulations to Harriet Banks who successfully defended her PhD thesis this afternoon. Harriet’s thesis explored biological mechanisms underlying anti-TNF response in a T-cell/macrophage Co-culture model using scRNAseq. #veryproudsupervisor
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Carl Anderson @carlanderson.bsky.social · 22/11/2024
Common variants don’t contribute to rare diseases, right? Wrong! Wonderful work published in Nature by @hilarycmartin.bsky.social, Qinqin Huang, @emiliewigdor.bsky.social and others in the Human Genetics Programme at Sanger showing that common vars contribute to rare neurodevelopmental diseases.
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Carl Anderson @carlanderson.bsky.social · 21/11/2024
Great way to end a fun day. Spent my whole day working closely with my team on our science, and now I’m at a Brownies campfire with my daughter.
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Carl Anderson @carlanderson.bsky.social · 17/11/2024
Oh man. I just lost my streak on #duolingo. I was almost at 365 days (358 I think). I’m way more gutted about this than I expected to be! 🥺
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Carl Anderson @carlanderson.bsky.social · 14/11/2024
Well, this is a breath of fresh air. There is something really exciting about this blank slate. Hello BlueSky!
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