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Brigette D. Manohar

@bmanohar.bsky.social
26 followers 47 following 2 posts

@fiubiomed ‘20 | @berkeleymcb PhD candidate @ the Wilson Lab, IGI 🧫| working on novel CRISPR based therapeutics for PD & non-viral delivery to the brain

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Reposted by Brigette D. Manohar
Adrian Woolfson @adrianwoolfson.bsky.social · 15/12/2025
Non-viral delivery of CRISPR components to the brain using peptide-enabled ribonucleoproteins www.biorxiv.org/content/10.1...
biorxiv.org
Efficient in vivo mammalian neuron editing using peptide-mediated CRISPR enzyme delivery
CRISPR-mediated genome editing of the central nervous system (CNS) has the potential to revolutionize the treatment of neurological disorders, including neurodegenerative disorders such as Huntington’...
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Brigette D. Manohar @bmanohar.bsky.social · 02/12/2025
Honored that this work represents my first "first-author" preprint of my PhD journey at @berkeleymcb.bsky.social. Grateful for the incredible mentorship and collaborations. Neuro-PERC was a true multi-institution effort. Read the thread for the details!
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Reposted by Brigette D. Manohar
Ross Wilson @rosswilsonlab.org · 02/12/2025
Huge credit to @bmanohar.bsky.social for leading this collaborative effort, based at @innovativegenomics.bsky.social & @berkeleymcb.bsky.social, with major contributions from OSU's Krys Bankiewicz & Russ Lonser, as well as crucial support from NIH's SCGE consortium @scge.bsky.social
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Reposted by Brigette D. Manohar
bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 30/11/2025
Efficient in vivo mammalian neuron editing using peptide-mediated CRISPR enzyme delivery www.biorxiv.org/content/10.1101/202…
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Brigette D. Manohar @bmanohar.bsky.social · 02/12/2025
Sweater weather ☃️❄️
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Reposted by Brigette D. Manohar
Science Magazine @science.org · 01/12/2025
Newly discovered fossils tie this foot to a primitive human relative known as Australopithecus deyiremeda, an enigmatic contemporary of A. afarensis, whose species included the famed Lucy skeleton. scim.ag/4414MEj
scim.ag
A puzzling, 3.4-million-year-old fossil foot belonged to a contemporary of the famed Lucy
Identity of the toe bones and other fossils could shake up the human family tree
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Reposted by Brigette D. Manohar
Innovative Genomics Institute @innovativegenomics.bsky.social · 26/11/2025
For the second year in a row, IGI had a booth at #NDiSTEM, the annual conference from SACNAS! More than a hundred students stopped by to learn about IGI and opportunities at the University of California.
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