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Alessio Quaresima

@bluedebris.bsky.social
238 followers 562 following 67 posts

Researcher in computational neuroscience. Interested in memory and perception! Working with a great team @BathellierLab, Institut de l'Audition, Paris. Personal page: aquaresima.github.io Julia Spiking Neural Networks: bit.ly/4mAbRly

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Alessio Quaresima @bluedebris.bsky.social · 25/09/2026
looking forward to this!!!
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Reposted by Alessio Quaresima
Maciej Kania @kaniamaciej.bsky.social · 25/09/2026
Train your model on a task, or fit it to biological data? And once it's optimized, what does it tell us about the brain? 🧠 In our #BernsteinConference satellite workshop, we'll discuss these questions through the lenses of different optimization methods. Check it out in Room 3.104! 🤓😉
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Nicole Rust @nicolecrust.bsky.social · 11/03/2026
Ruffling some feathers, it's fascinating to ask: What forces drive this plot? To what degree is our community targeting important challenges and creating impactful solutions vs caught up in the inertia of curiosity and opportunity? For instance, ... /1
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Alessio Quaresima @bluedebris.bsky.social · 21/01/2026
I mean, the only good thing about current international political affairs is that if they go all in on cannons maybe they stop building these dumbass tech
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Alessio Quaresima @bluedebris.bsky.social · 21/01/2026
Really? Who would have thought about it?!?
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Alessio Quaresima @bluedebris.bsky.social · 09/01/2026
Considering they re popular among tech bros it could be good news
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Alessio Quaresima @bluedebris.bsky.social · 14/12/2025
Okok, the comparison works only in ML. We can't look up the past inputs to make predictions about the future. Is reservoir just a possible memory implementation?
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Alessio Quaresima @bluedebris.bsky.social · 14/12/2025
RC is indeed quite a cool computational framework, however it has shortcomings. 1. Where is the supervised decoder? 2. How do you motivate learning? (But see recent @bconfavreux.bsky.social work) I dug the rabbit hole and found this: www.nature.com/articles/s41... You can do RC without network 🤣
nature.com
Next generation reservoir computing - Nature Communications
Reservoir computers are artificial neural networks that can be trained on small data sets, but require large random matrices and numerous metaparameters. The authors propose an improved reservoir comp...
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Alessio Quaresima @bluedebris.bsky.social · 14/12/2025
Hire people not AI
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Alessio Quaresima @bluedebris.bsky.social · 12/12/2025
Recorded :) ?
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Neurospeech Team @neurospeech.bsky.social · 15/10/2025
Our review "Neuro-oscillatory models of cortical speech processing", authored by Olesia Dogonasheva, has finally been published. Check it below ⬇️ #compneuro #neuroskyence #EEG
sciencedirect.com
Neuro-oscillatory models of cortical speech processing
In this review, we examine computational models that explore the role of neural oscillations in speech perception, spanning from early auditory proces…
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Alessio Quaresima @bluedebris.bsky.social · 14/10/2025
When you are debugging and this song comes up three times on your playlist, you can't help but wonder, "Why do they scream OREGANO??" link.deezer.com/s/31jU4pHH39...
link.deezer.com
Only God Knows
Young Fathers - album - 2017 - 1 song
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Alessio Quaresima @bluedebris.bsky.social · 10/10/2025
Sure, in the end, everything is an RNN ;) Mongillo's model indeed requires pre-formed attractors. However, that model opens up to other sub-threshold memory mechanisms that can maintain STM when LTMs are not present, yet.
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Alessio Quaresima @bluedebris.bsky.social · 10/10/2025
So maybe if an RNN has memory that scales up with the size, it is a better model of activated LTM rather than of STM. No?
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Alessio Quaresima @bluedebris.bsky.social · 09/10/2025
4-7 *new* items! If you learn to use a retrieval structure, you go pretty big - as all those crazy memorists do! online WM of novel items require variable binding, and I doubt you can get it in RNNs. Check this out for a cogsci perspective pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov
Short-Term Memory and Long-Term Memory are Still Different
A commonly expressed view is that short-term memory (STM) is nothing more than activated long-term memory. If true, this would overturn a central tenet of cognitive psychology—the idea that there are ...
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Alessio Quaresima @bluedebris.bsky.social · 09/10/2025
IMHO. Because it does not have "memory slots" ready for it, if it has memory slots, it lacks the machinery to convert them back into sensory representations. But you're the RNN expert, if you say it, I believe you ;)
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Alessio Quaresima @bluedebris.bsky.social · 09/10/2025
Can it distinguish a shape it saw once from one it never saw? And despite visual distractors?
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Alessio Quaresima @bluedebris.bsky.social · 09/10/2025
Maybe we do have five stable attractors in pfc and use them to re-cue sensory perceptions. But we need to be clear about active/silent interactions to move forward in this direction.
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Alessio Quaresima @bluedebris.bsky.social · 09/10/2025
True. However, the attractor `iff` pers. activity is the case only if we consider the firing rate as the only variable at play in the brain. Any cognitive theory of WM requires the allocation of new items on the fly. Can we build attractors through single-shot learning? Or we repurpose the same?
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Alessio Quaresima @bluedebris.bsky.social · 09/10/2025
True! However, we have learned about long-term memory formation and maintenance from snails. Divergent evolutionary paths can yet implement similar computational mechanisms. IMHO, recurrent activity is not as prominent in monkey's PFC as in fruitfly MB, but the comparison holds.
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Alessio Quaresima @bluedebris.bsky.social · 07/10/2025
If you're still updating the starter pack, add me in ;)
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Alessio Quaresima @bluedebris.bsky.social · 07/10/2025
I want to be the guy on the left. libera nos domine de AI
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Alessio Quaresima @bluedebris.bsky.social · 07/10/2025
In the image I see a mid age person with a wise face and - probably - mastering a complex software Vs a youngster with a naive smile clicking buttons on an anonymous interface while the world burns
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Alessio Quaresima @bluedebris.bsky.social · 06/10/2025
Then send a link to the blog ;)
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Alessio Quaresima @bluedebris.bsky.social · 01/10/2025
At #BernsteinConference heated debate on WM mechanisms. I love that this is still far to be settled! trained RNNs from A.Compte aligns with fruitfly direction WM data from K.Nagel: it is persistent. Large scale recording in macaque V1 in T.Moore Lab: it is not. #neuroskyence what's your take?
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Alessio Quaresima @bluedebris.bsky.social · 30/09/2025
And concluding with a beautiful thermodynamics of learning: The correct learning rate depends on the noise of the training set (sigma eta)!
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Alessio Quaresima @bluedebris.bsky.social · 30/09/2025
And reminding the great neuroscientist **and middle east pacifist** Daniel Amit!
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Alessio Quaresima @bluedebris.bsky.social · 30/09/2025
So cool to walk from Ising models to recurrent network dynamics at the Braitenberg prize ceremony of Sara Solla! At #bernstein conference #compneurosky
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Alessio Quaresima @bluedebris.bsky.social · 26/09/2025
The library strikes a balance between creating new models and composing them in fairly complex networks. If you would like some specific feat and cannot achieve it, just contact me and we'll find a way together!
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Alessio Quaresima @bluedebris.bsky.social · 26/09/2025
Hey #neuroskyence and #compneurosky I recently released this #Julia library for simulating Spiking Neural Networks! bit.ly/4mAbRly As with everything in Julia, it is fast, elegant, and compact! Check out the documentation and the tutorials to get an idea!
bit.ly
SpikingNeuralNetworks.jl Documentation · Julia SpikingNeuralNetworks
Documentation for Julia SpikingNeuralNetworks.
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Alessio Quaresima @bluedebris.bsky.social · 17/09/2025
Where do they get all this money to infest our market anyway???
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Alessio Quaresima @bluedebris.bsky.social · 16/09/2025
And yess! The students loved it :)
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Alessio Quaresima @bluedebris.bsky.social · 14/09/2025
Hey #neuroskyence #compneurosky I made this interactive tool for showing the phase planes of 2D neuron models to studs! Have fun :) github.com/JuliaSNN/Com...
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Alessio Quaresima @bluedebris.bsky.social · 12/09/2025
Thank you! I wanted to feel better this mornin 🤣
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PessoaBrain @pessoabrain.bsky.social · 09/09/2025
𝗕𝗿𝗮𝗶𝗻-𝘄𝗶𝗱𝗲 𝗰𝗼𝗺𝗽𝘂𝘁𝗮𝘁𝗶𝗼𝗻𝘀 Spatially distributed and regionally unbound cellular resolution brain-wide processing loops in mice 𝗕𝗿𝗮𝗶𝗻 𝗿𝗲𝗴𝗶𝗼𝗻𝘀 𝗼𝗿 𝗱𝘆𝗻𝗮𝗺𝗶𝗰 𝘁𝗵𝗿𝗲𝗮𝗱𝘀? Dynamical processing winding through most brain regions. Looks like a must read. www.biorxiv.org/content/10.1... #neuroskyence
biorxiv.org
Spatially distributed and regionally unbound cellular resolution brain-wide processing loops in mice
Until recently, it has been possible to examine activity in the brain globally through regional averaging or locally at cellular resolution. These studies characterized regions as functionally homogen...
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Nature Portfolio @natureportfolio.nature.com · 09/09/2025
The International Brain Laboratory presents in Nature a brain-wide electrophysiological map that represents a resource for understanding how computations distributed across and within brain areas drive behaviour. go.nature.com/4nnnmhg 🧪 🧠📈
This is figure 2, which shows brain-wide recordings during behaviour.
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Neurofrontiers @neuro-frontiers.bsky.social · 22/08/2025
Progesterone is another sex hormone best known for its effects on the female reproductive system. Similar to estrogens, however, it’s becoming increasingly clearer that progesterone impacts many more systems in the body, both in females and in males. #neuroskyence #skyence #hormones
neurofrontiers.blog
Progesterone in the brain - Neurofrontiers
Progesterone is a sex hormone with broad effects beyond the reproductive system, in particular in the brain.
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Alessio Quaresima @bluedebris.bsky.social · 21/08/2025
Will this be online?
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Alessio Quaresima @bluedebris.bsky.social · 15/07/2025
There are examples of different IPSP dependently on the location of the afferent on the postsynaptic neuron. That would do?
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Alessio Quaresima @bluedebris.bsky.social · 05/07/2025
I don't understand, whats the problem if people use chatgpt to write part of their text? Like, the write the prompt with the info in bullet points, and ask for a text. Is this any type of scientific fraud?
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Alessio Quaresima @bluedebris.bsky.social · 04/07/2025
What a time when you could title your paper like this!
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Alessio Quaresima @bluedebris.bsky.social · 04/07/2025
@imbizo.bsky.social Hey! Great school! Are teaching assistants applications still open?
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Max Planck Institute for Psycholinguistics @mpi-nl.bsky.social · 30/06/2025
Nonlinear dendritic integration supports Up-Down states in single neurons. Paper by @bluedebris.bsky.social & al. With Hartmut Fitz, Peter Hagoort doi.org/10.1523/JNEUROSCI.1701-24.2025 Paper: tinyurl.com/34pptvv5
doi.org
Nonlinear Dendritic Integration Supports Up–Down States in Single Neurons
Changes in the activity profile of cortical neurons are due to effects at the scale of local and long-range networks. Accordingly, abrupt transitions in the state of cortical neurons—a phenomenon know...
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James Vornov @jjvornov.bsky.social · 24/06/2025
The neuroscience tale of how purple, really magenta, is a synthetic color not found on the spectrum. We don't perceive the environment, but become aware of the brain's processing of color. I conclude, Kant was right, there is a priori knowledge. But he never realized it was neuronal. #neuroskyence
open.substack.com
If Purple isn’t real, then what is?
Let’s talk epistemology. Actually, let’s have magenta and cyan bid farewell to epistemology altogether
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Alessio Quaresima @bluedebris.bsky.social · 22/06/2025
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Penn NeuroKnow 🧠 @pennneuroknow.bsky.social · 10/06/2025
How does climate change impact the brain? Spoiler alert: it’s not looking good.. Check out this week's piece where @pennngg.bsky.social student Margaret Gardner dives into this chilling topic: pennneuroknow.com/2025/06/10/c... #neuroskyence #PsychSciSky #SciComm
pennneuroknow.com
Changing Climate, Changing Brains
How does climate change impact the brain? Spoiler alert: it’s not good
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Alessio Quaresima @bluedebris.bsky.social · 23/05/2025
It feels like a Harry Potter book... www.nytimes.com/2025/05/22/u...
nytimes.com
Trump Administration Says It Is Halting Harvard’s Ability to Enroll International Students
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Dirk Gütlin @gutlin.bsky.social · 19/05/2025
Dopaminergic action prediction errors serve as a value-free teaching signal www.nature.com/articles/s41...
nature.com
Dopaminergic action prediction errors serve as a value-free teaching signal - Nature
Dopaminergic action prediction error signals are used by mice as a value-free teaching signal to reinforce stable sound–action associations in the tail of the striatum.
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Alessio Quaresima @bluedebris.bsky.social · 19/05/2025
I understand, but don't these apply to attractors theory too? I mean, I dunno much about PVT, just saying attractor states are a powerful abstraction and can account for permanent states on top of a biological, changing substrate
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Alessio Quaresima @bluedebris.bsky.social · 18/05/2025
what about attractor states?? Even if not still, they are permanent, self sustained states. They can also exist on longer timescales of working memory. Any memory is an example that such states exist...
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