AbstractMotivation. The presence or absence of some genes in a genome can influence whether other genes are likely to be present or absent. Understanding t

The accessory genome of Mycobacterium tuberculosis is small, but differences in gene content are found both between and within lineages.

The Mycobacterium tuberculosis complex (MTBC) is a group of bacteria causing tuberculosis (TB) in humans and animals. Understanding MTBC genetic diversity is crucial for insights into its adaptation a...

The Department of Molecular Biology seeks a postdoctoral researcher who will work with forecasting and steering experimental evolution of antibiotic resistance. The employment is full-time for two yea

Find out about this studentship opportunity on Health inequalities which impact the treatment of urinary tract infections.

In this work, authors probe the molecular mechanism of re-emerging CHL susceptibility in Malawian Enterobacterales isolates, where they identify a stable truncation of resistance genes by insertion se...

npj Antimicrobials and Resistance - The effect of antibiotic selection on collateral effects and evolvability of uropathogenic Escherichia coli

npj Antimicrobials and Resistance - The effect of antibiotic selection on collateral effects and evolvability of uropathogenic Escherichia coli

bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Inferring the evolutionary history of prokaryotic pangenomes is complicated by the lack of a reference for neutral genetic variation. A study that uses pseudogenes as a neutral reference provides supp...