Blended genome exome (BGE) is a sequencing method that captures genetic variation in an unbiased and cost-effective manner. Applying BGE to sequence samples from underrepresented populations leads to ...

Podcast Episode · Empowered Patient Podcast · June 18 · 22m

The Heinz C. Prechter Bipolar Research Program presents "Inside the Study" featuring research and lived experience experts, Dr. Kelly Ryan, Christine Grimm, N.P., Dr. Alexandra Vinson, and Sarah, and moderated by Jack DiCarlantonio. This webinar highlights the BD²: Breakthrough Discoveries for Thriving with Bipolar Disorder research study. In 2023, the Heinz C. Prechter Bipolar Research Program was named as one of the six inaugural institutions in the BD² Integrated Network to engage people living with bipolar disorder in a long-term research study and build a rich database to better understand the condition, its treatment, and to support improvements in care. The BD² Integrated Network has since expanded its clinical sites to 11 institutions across the United States and Canada. Along with the long-term studies and databases, the BD² Integrated Network sites are working together to design and implement a Learning Health Network (LHN) for bipolar disorder. Learn more about the background of the Prechter Program’s role in the BD²: Breakthrough Discoveries for Thriving with Bipolar Disorder study, what participation is like, what the team is finding so far, and more. Learn more: - Heinz C. Prechter Bipolar Research Program: https://medresearch.umich.edu/labs-departments/centers/prechter-program - BD²: Breakthrough Discoveries for Thriving with Bipolar Disorder: https://medresearch.umich.edu/labs-departments/centers/prechter-program/research/breakthrough-discoveries-thriving-bipolar-disorder - BD² Integrated Network: https://www.bipolardiscoveries.org/our-work/integrated-network/

The BD2 initiative has been assembling an international network to coordinate research and standards of care. Backers include Sergey Brin and Dalio Philanthropies.

How can better data transform bipolar disorder research, diagnosis, and care? In this BD² conversation, leaders from the BD² Integrated Network discuss the first public release of data from the Integrated Network Longitudinal Cohort Study — a major milestone in bipolar disorder research and one of the most comprehensive efforts to understand the complexity, heterogeneity, and long-term course of the condition. Hosted by Emily Baxi, PhD, Program Director of the BD² Integrated Network, this discussion features Cara Altimus, PhD, CEO of BD²; Katherine “Kate” Burdick, PhD; Mark Frye, MD, Scientific Directors; and Mojib Javadi, PhD, Lead of the Data Coordinating Center. Together, they explore why this dataset matters, how it was built, and how it could accelerate progress in bipolar disorder diagnosis, biomarkers, treatment development, and precision psychiatry. In this video, you’ll learn: 0:00–4:28 – Why bipolar disorder research has historically been fragmented, underfunded, and limited in scale 4:28–9:15 – How the BD² Integrated Network was designed to connect clinicians, researchers, and people with lived experience 9:15–11:52 – What makes this dataset unique, including longitudinal, multi-modal, and standardized data collection 11:52–16:31 – How collaboration, data sharing, and research working groups can accelerate discovery 16:31–23:44 – How researchers can use this data to study heterogeneity, identify biomarkers, and improve treatment strategies 23:44–32:46 – How the Learning Health Network helps connect research insights back to real-world care 32:46–38:23 – What this milestone could make possible for the next five years of bipolar disorder research and precision medicine This conversation shows how large-scale, collaborative mental health research can close long-standing gaps in psychiatry and move the field toward more personalized, evidence-based care for people living with bipolar disorder. 🔔 Subscribe for more conversations on bipolar disorder research, neuroscience, mental health innovation, and lived experience. 🔗 Learn more about the BD² Integrated Network: https://www.bipolardiscoveries.org/our-work/integrated-network/ #BipolarDisorder #MentalHealthResearch #PrecisionMedicine #Neuroscience

An exclusive event co-hosted by Rockefeller Neuroscience Institute and Scientific American Custom Media --------- Please join us on April 22nd for an engaging…

The Humans of the Wyss (HOW) series features members of the Wyss community discussing their work, the influences that shape them as professionals, and their collaborations at the Wyss Institute and be...