iiinova — where your digital self keeps evolving

BIC_Bordeaux @bic-bordeaux.bsky.social · 07/10/2026

🧠💡 #ImageOfTheMonth October 2026: 3D cerebral vascular network via iDISCO⁺ & light-sheet microscopy. Capillaries/veins (blue) & arteries (red) in adult mouse. E.Casas/C.Peghaire/T.Couffinhal (VBHI) Collaboration with: N.Renier /L. Mathé/S.Debette (ICM) | J.Teillon (BIC). #Neuro #Imaging #Science

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BIC_Bordeaux @bic-bordeaux.bsky.social · 02/09/2026

#ImageOfTheMonth September 2026 🍇 15 µm Vitis vinifera wood cross-section (Safranin/Astra Blue). Xylem vessels revealed segmentation. Image by Samuele Moretti, Nathalie Ferrer, @chloedelmas.bsky.social (SAVE) & Guillaume Maucort (BIC). #PlantScience #Microscopy #BIC

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Louise Fougere @louisefougere.bsky.social · 14/08/2026

Super happy to share with Magali Grison, @yohannboutte.bsky.social and Christel Poujol this amazing method of super-resolution in plant-cell microscopy 🤗 always further ! always more extraordinary !🔬 🪴 @lbm-bordeaux.bsky.social @bic-bordeaux.bsky.social @univbordeaux.bsky.social

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BIC_Bordeaux @bic-bordeaux.bsky.social · 04/08/2026

#ImageOfTheMonth August 2026 🔬 Stunning 8x expanded human hippocampus! Microglia (pink), lysosomes (yellow), nuclei (grey). Collaboration: Ana Victoria Prádanos Senén (@cbm-csic-uam.bsky.social) & @monica-bic.bsky.social (BIC). #Neuroscience #ExpansionMicroscopy

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BIC_Bordeaux @bic-bordeaux.bsky.social · 01/07/2026

#ImageOfTheMonth July 2026 🌿✨ Spotlight on Alizé Chambard @inrae-bfp.bsky.social Confocal image of an Arabidopsis thaliana leaf cross-section 🟢 GFP-tagged virus from @lbm-bordeaux.bsky.social 🟠 Plasmodesmata 🔵 Cell walls 🟣 Plastids A masterpiece of in resin fluorescence & immunolabeling ! 🎨🔬

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France-BioImaging @france-bioimaging.bsky.social · 18/06/2026

SFBS 2026 is taking shape 👀 Discover the first programme highlights of our symposium dedicated to super-resolution microscopy and advanced optical imaging Good news: abstract submission & early bird registration are extended until June 30! More info👉 france-bioimaging.org/announcement...

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BIC_Bordeaux @bic-bordeaux.bsky.social · 18/06/2026

A huge thank you to the ELMI crew - you made this conference run so smoothly and enjoyably! #ELMI2026 @ppbioimaging.bsky.social

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BIC_Bordeaux @bic-bordeaux.bsky.social · 03/06/2026

#ImageOfTheMonth June 2026 🔬 T-tubules in mouse muscle: anti-Dynamin-2 + 10nm gold particles (black dots) for Charcot disease study. Tokuyasu technique (cryosectioning + gold immunolabeling) + TEM imaging. From Chadia Nahy (IGBMC) & Melina Petrel (BIC) #EM #MuscleResearch #CharcotDisease #Tokuyasu

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France-BioImaging @france-bioimaging.bsky.social · 27/05/2026

New speakers of SFBS 2026 are being revealed... ...but you'll have to swipe to discover who they are! Find out more👉https://france-bioimaging.org/announcement/sfbs-2026-new-speakers-are-revealed/ 📍Oct. 19 to 21, 2026 - Bordeaux 🇫🇷 🚨D-15 before early bird registration closing!

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Rémi Fronzes @fronzeslab.bsky.social · 28/04/2026

Still possible to register for the 14th Young Scientists' Symposium! 📅 4-5 June 2026 @iecb.bsky.social @univbordeaux.bsky.social Fantastic lineup of keynote speakers. @marionjasnin.bsky.social @amjjbonvin.bsky.social @olallalab.bsky.social

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BIC_Bordeaux @bic-bordeaux.bsky.social · 07/05/2026

#ImageOfTheMonth May 2026 🌟 Astrocytes in action! Cytoskeletal proteins in rat cortical astrocytes (DIV16), captured with simple widefield microscopy. A beautiful, informative glimpse into intercellular networks. Credit: Tatiana Charbonnier (IINS UMR 5297) #Neuroscience #Astrocytes #Microscopy

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France-BioImaging @france-bioimaging.bsky.social · 29/04/2026

🚨Last call - 2 days left to apply for the SFBS 2026 Advanced Workshop! Learn how to choose, implement and interpret super-resolution imaging techniques (SMLM, STED, and more). Workshop & international symposium access included Deadline: May 1, 2026 👉 france-bioimaging.org/news-events/...

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BIC_Bordeaux @bic-bordeaux.bsky.social · 31/03/2026

Mathieu (proudly) representing the BIC #FOM2026. It's happening now !

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BIC_Bordeaux @bic-bordeaux.bsky.social · 27/03/2026

Yesterday, the 4 teams of the BIC spent a very nice moment together. We had presentations from the newest members of the BIC (and not so newest), and a shared lunch on the sunny terasse of the INRAE campus !

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BIC_Bordeaux @bic-bordeaux.bsky.social · 17/03/2026

This week, engineers from the photonics division are leading the longest-running course in our catalog: The Basics of Wide-Field and Confocal Microscopy !

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France-BioImaging @france-bioimaging.bsky.social · 16/03/2026

[EVENT] Registrations are now open for the SFBS-2026 Join us in Bordeaux (Oct 14–21, 2026) for an advanced workshop and an international symposium 📆Workshop application deadline: May, 1 📆Symposium early bird registration deadline: June, 15 More info👉 france-bioimaging.org/news-events/...

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BIC_Bordeaux @bic-bordeaux.bsky.social · 13/03/2026

This week @jeremie-bic.bsky.social presented his work on sample clearing and light-sheet imaging during @france-bioimaging.bsky.social annual meeting. This is the pure définition of the "Whaou" effect! Congrats !!!

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Laboratoire de Biogenèse Membranaire @lbm-bordeaux.bsky.social · 09/03/2026

Interested in plant biology and super-resolution microscopy? This EMBL workshop is for you! You will learn how efficient tau-STED Xtend is in Arabidopsis root tip. With Christel Poujol @bic-bordeaux.bsky.social and Magali Grison from our Lab, register before April 6th! www.embl.org/about/info/c...

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BIC_Bordeaux @bic-bordeaux.bsky.social · 02/03/2026

#ImageOfTheMonth March 2026 Dividing Arabidopsis epidermal cells imaged by confocal microscopy after expansion. Microtubules guided cell plate formation revealed in 3D with depth-code. Image: Magali Grison @lbm-bordeaux.bsky.social @gtexm.bsky.social #Microscopy #PlantScience #CellBiology

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IECB Bordeaux @iecb.bsky.social · 29/01/2026

Save the date 🤩🤩🤩! Our student-led Young Scientist Symposium will take place on the 4th & 5th of June this summer! More information and registration available soon!

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BIC_Bordeaux @bic-bordeaux.bsky.social · 02/02/2026

🏆 Image of the Year 2025 226 votes, 12 Images of the Month, and a race decided by just one vote 😮 With 58 votes, @tdhellemmes.bsky.social wins for his cleared brain image acquired using light-sheet microscopy and will proudly carry the colors of the BIC 🎉🔬✨

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BIC_Bordeaux @bic-bordeaux.bsky.social · 02/02/2026

#ImageOfTheMonth February 2026 ✨ Fluorescent fibers (hundreds of µm) of a Platinium complex visualized in Fiji using orientation-based pseudocolors 🎨. Image acquired during the BIC hands-on microscopy training 🔬 Credits: F. R. Lauro, A. Virepinte (ISM), J. Teillon (BIC)

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France-BioImaging @france-bioimaging.bsky.social · 26/01/2026

[WEBINAR] Join the next France Volume-EM WebCafe! Karin Pernet-Gallay from the GIN (Grenoble) will present her latest project, revealing new insights into astrocyte structure & function. These results would never have been obtained without 3D EM! 🗓️ January, 29th - 13:00 🔗 Join here: bit.ly/49Ux45l

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BIC_Bordeaux @bic-bordeaux.bsky.social · 23/01/2026

✨ En ce début d’année, l’équipe du pôle photonique s’est dit qu’il était temps de changer des slides et des listes d’équipements 📄❌ 👉 Résultat : un mini-film un peu décalé pour présenter nos systèmes de microscopie, d’optique et d’instrumentation 🔬 La photonique, mais en version musicale 🎶

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BIC_Bordeaux @bic-bordeaux.bsky.social · 02/01/2026

A colorful start to 2026! 🌿 #ImageOfTheMonth M. Batsale (Plant Virology team, @inrae-bfp.bsky.social ) captured a Nicotiana benthamiana cell infected with turnip mosaic virus — peroxisomes (yellow), viral vesicles (magenta) & chloroplasts (blue).

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BIC_Bordeaux @bic-bordeaux.bsky.social · 04/12/2025

✨ December 2025 #ImageOfTheMonth ✨ Whole rat hearts cleared with iDISCO reveal sympathetic innervation (orange) and vascularization (green). 💛💚 Work by S. Bertrand & A. Bonilla (INCIA) with S. Martin & I. Brunet (CIRB), imaged by J. Teillon (BIC). #Microscopy #iDISCO #BICBordeaux

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BIC_Bordeaux @bic-bordeaux.bsky.social · 03/11/2025

November #ImageOfTheMonth goes to M.Pujol from LPCO lab (UMR 5629). Acquired with Transmission Electron Microscopy, it shows a polystyrene (PS) latex obtained by post-dispersion of a yogurt cup made of PS in water using a surfactant. The resulting particles are highly heterogeneous and large.

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BIC_Bordeaux @bic-bordeaux.bsky.social · 07/10/2025

‪October #ImageOfTheMonth is from O. Barba-Vila from @iins-bordeaux.bsky.social Slice of the gustatory cortex showing axons from the gustatory thalamus (G), basolateral amygdala (R) and a thick-tufted layer 5 neuron (W), recorded through patch clamp and imaged via biocytin-streptavidin labelling

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BIC_Bordeaux @bic-bordeaux.bsky.social · 08/09/2025

September #ImageOfTheMonth is from @rkinet.bsky.social from @imn-bordeaux.bsky.social This is a maximum projection of a confocal image of a microglia cell (blue) and its nucleus (red), internalising multiple nanoparticles (yellow), one day after supranigral injection in C57B6-J mouse

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BIC_Bordeaux @bic-bordeaux.bsky.social · 07/08/2025

August #ImageOfTheMonth is from L.Congiu from @imn-bordeaux.bsky.social. This is a 3D reconstruction of a CD68-positive particles (white) within the cell body of microglia cells (Red) in the mouse cortex. The confocal Z-stack was processed with Imaris software.

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Ana Dorrego Rivas @adorrego.bsky.social · 23/07/2025

It’s good to be back at the BIC! @bic-bordeaux.bsky.social 🔬

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BIC_Bordeaux @bic-bordeaux.bsky.social · 04/07/2025

July #ImageOfTheMonth is from A.Drouet from @iins-bordeaux.bsky.social. This image represents a neurosphere (150x150 µm) formed from dissociated hippocampal neurons cultured for 14 days under non-adhesive conditions. Yellow shows GFP expressing neurons and nuclei are showed in cyan.

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BIC_Bordeaux @bic-bordeaux.bsky.social · 05/06/2025

June #ImageOfTheMonth is from L.Boutaleb from @inrae-bfp.bsky.social. They study the impact of heat stress on cell division and DNA replication on the tomato meristem. On this confocal image, EdU staining (magenta) detects replicating DNA and Hoechst labeling (cyan) shows all cell nuclei.

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BIC_Bordeaux @bic-bordeaux.bsky.social · 05/06/2025

May #ImageOfTheMonth was from C.Mazocco & M.Darricau from @imn-bordeaux.bsky.social. Staining on spinal cord slices reveal TDP43 protein in the nucleus of neurons (Red). Motoneurons and synaptic terminations were stained targetting ChAT (Cyan).

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Emmanuelle Bayer @emmanuellebayer.bsky.social · 17/04/2025

Time to expand your vision! 👀🌱 Our latest work on ExM in plants is out Back-to-back with the Danzl 's lab (@ISTAustria) led by Magali Grison @lbm-bordeaux.bsky.social with @monica-bic.bsky.social and @gmaucort.bsky.social from the @bic-bordeaux.bsky.social . academic.oup.com/plcell/artic...

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Monica_BIC @monica-bic.bsky.social · 14/04/2025

Finally out!, after a few months of delay, our protocol on ExM in plant roots is now available in The Plant Cell academic.oup.com/plcell/artic... Beautiful images in a great collaboration of the @bic-bordeaux.bsky.social with @emmanuellebayer.bsky.social and Magali Grison @lbm-bordeaux.bsky.social

academic.oup.com

Root expansion microscopy: A robust method for super resolution imaging in Arabidopsis

Root expansion microscopy (ROOT-ExM) achieves super-resolution expansion microscopy in plants.

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BIC_Bordeaux @bic-bordeaux.bsky.social · 01/04/2025

April #ImageOfTheMonth is from H. Vaïtinadapoulé (BiiO EA 2521). Here is a guttae, a “drop-like deposits” of extracellular matrix components on the surface of the cornea. This image was acquired using scanning electron microscopy with the help of F.Decoeur from the EM unit of the BIC.

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BIC_Bordeaux @bic-bordeaux.bsky.social · 03/03/2025

March #ImageOfTheMonth goes to M.Bonhivers from MFP lab (UMR 5234). Trypanosoma brucei cell was extracted in detergent, expanded 4.2 fold using U-ExM, labelled for the microtubule cytoskeleton (magenta) and for the Hook Complex (yellow), and images usinf scanning confocal microscopy.

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Yohann Boutté @yohannboutte.bsky.social · 25/02/2025

Super-resolution microscopy unravels a dynamic tubular network that is stabilized by pre-existing Golgi and lipids to mature into new Golgi pre-cisternae, @bic-bordeaux.bsky.social, @cnrsbiologie.bsky.social, @cnrsaquitaine.bsky.social, #Lipids, #ExpansionMicroscopy, #PlantScience, #PlantCellBiology

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DChoquet @danielchoquet.bsky.social · 05/02/2025

Save the date ! Frontiers in Neurophotonics Symposium 2025 in Bordeaux October 6-9 frontiersneurophotonics.org/2025-speakers/ 🧪

frontiersneurophotonics.org

2025 Speakers – International Frontiers in Neurophotonics Symposium

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BIC_Bordeaux @bic-bordeaux.bsky.social · 03/02/2025

Top pictures display dorso-to-ventral samples of bottom max projection (from left to right).

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BIC_Bordeaux @bic-bordeaux.bsky.social · 03/02/2025

February #ImageOfTheMonth is from @tdhellemmes.bsky.social . GFP expressing Relaxin3 neurons from the nucleus incertus and their projections are followed through the whole mouse brain using Adipoclear+ method and Light Sheet microscopy. Scale:1mm

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BIC_Bordeaux @bic-bordeaux.bsky.social · 05/01/2025

Happy new year! Let's start 2025 with an #ImageOfTheMonth from N. Bollier @inrae-bfp.bsky.social. Scanning confocal 3D reconstruction of a tomato shoot apical meristem. The fixed meristem was cleared using clearsee and the cell walls are stained by calcofluor white.

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Thibault Dhellemmes @tdhellemmes.bsky.social · 30/12/2024

Kaleidoscopic view of my tracing experiment, from top to bottom. Our great achievement with @jeremie-bic.bsky.social in @bic-bordeaux.bsky.social for @imn-bordeaux.bsky.social

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Thibault Dhellemmes @tdhellemmes.bsky.social · 29/12/2024

Icing stars and flowers in electron microscopy. With the courtesy of Isabelle Svahn in @neurobordeaux.bsky.social and @bic-bordeaux.bsky.social

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BIC_Bordeaux @bic-bordeaux.bsky.social · 12/12/2024

Hello, the BIC is starting its Bluesky experience with its December #ImageOfTheMonth. Beautiful rat neurons imaged in STED 😍 by T.Cloâtre from @iins-bordeaux.bsky.social !

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