Pharmacogenomics is often promoted as a way to personalise treatment, but how useful is it for medicines commonly used in chronic pain? In a new preprint, we examined whether variation in the CYP2C19...

A novel multistep strategy reveals how parent-of-origin effects shape complex traits in large-scale biobanks.

A human ascending somatosensory assembloid model was developed, which integrates multiple organoids to simulate the spinothalamic pathway, demonstrating functional connectivity and responsiveness to stimuli and revealing insights into pain-related genetic mutations.

The first robust association between a genetic variant and disease risk.

After transplantation into the brain of patients with Parkinson’s disease, allogeneic dopaminergic progenitors derived from induced pluripotent stem cells survived, produced dopamine and did not form tumours, therefore suggesting safety and potential clinical benefits for Parkinson’s disease.

The immune-checkpoint molecule TIM-3 regulates microglial homeostasis, and its microglial-specific deletion reduced cognitive impairment in a mouse model of Alzheimer’s disease.

We've all been there: one bad oyster ruins seafood forever. Now, Princeton neuroscientists have pinpointed how the brain stores memories for these powerful food aversions in mice. The new results reve...

Nature - Hundreds of cubes of human brain tissue help scientists to chart the energy-making capabilities of various brain regions.

Ageing is a scientifically fascinating and complex biological occurrence characterised by morphological and functional changes due to accumulated molecular and cellular damage impairing tissue and org...

Assistant/Associate Professor in Computational Biology in the Department of Applied Mathematics and Theoretical Physics at the University of Cambridge.

The Broken Plate Report 2025 has found that too many people in the UK do not have the finances to access healthy, quality food. The report also evidences the fact […]

QIMR Berghofer is appealing for donations from the community to help researchers conduct an Australian-first study into the potential link between bushfire smoke exposure and dementia.