iiinova — where your digital self keeps evolving

Axel Olin @axelolin.bsky.social · 11/05/2026

📢 I’m recruiting a postdoc at KTH to work on virome-wide serology in the context of pandemic preparedness! The project will study antiviral immunity in the Swedish population using novel serological methods and blood self-sampling. Please share! Apply: www.kth.se/lediga-jobb/...

kth.se

KTH | Postdoc in Virome-wide Serology and Pandemic Preparedness

KTH jobs is where you search for jobs at www.kth.se.

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Axel Olin @axelolin.bsky.social · 09/04/2025

I understand that a high prediction accuracy reveals some connection between the variables and that it can be used to identify the most strongly associated omics variables. Still, it feels so backward to me. I don't need to do a bunch of omics to figure out how old I am. 🫠 2/2

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Axel Olin @axelolin.bsky.social · 09/04/2025

In exploratory omics studies in humans, it is quite common to evaluate the prediction accuracy of demographic variables like age and sex using the omics variables. In what situation would you actually need to do this? Isn't there some more natural statistical framework that makes more sense? 1/2

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Axel Olin @axelolin.bsky.social · 27/03/2025

75% is insane. Government loans for scientific funding would be a crazy good investment for countries that can afford it.

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Darragh Duffy @darraghduffy.bsky.social · 24/03/2025

13 chair positions open @inserm.fr to lead a junior research group in France covering #neuroscience, #immunology, #bioinformatics, #bioengineering, #biotherapy, #public health pro.inserm.fr/rubriques/co... 🧪🔬

pro.inserm.fr

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Axel Olin @axelolin.bsky.social · 22/03/2025

My sister was involved in a similar study in ecology. Even with a relatively simple dataset and guided by a research question, results were all over the place and did not correlate with reviewer assessment. I don't have high hopes for exploratory omics studies... link.springer.com/article/10.1...

link.springer.com

Same data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology - BMC Biology

Although variation in effect sizes and predicted values among studies of similar phenomena is inevitable, such variation far exceeds what might be produced by sampling error alone. One possible explan...

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Axel Olin @axelolin.bsky.social · 01/03/2025

The best thing Americans can do right now is minimizing domestic spending and donating to Ukraine: u24.gov.ua Europeans should also donate more, stop buying american, invest in EU defense stocks, and pressure their governments to donate more and ramp up defense spending.

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Aaron Rupar @atrupar.com · 26/02/2025

Complete batshit lunacy on the president's Truth Social account. Yes, he really posted this.

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Senator Chris Van Hollen @vanhollen.senate.gov · 24/02/2025

Today, the US stood with Russia and North Korea — and against our allies — in voting against a UN resolution to condemn Russia's aggression against Ukraine. Let that sink in. This is a betrayal of the Ukrainian people, our allies, our interests and those who aspire for freedom.

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Axel Olin @axelolin.bsky.social · 23/02/2025

Elon Musk literally just verified the account 'Adolf Hitler' as an official government account on his website. It is time for EU to block it, just like they blocked the website of the russian state-sponsored media channel RT. It is the source of so much misinformation.

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Axel Olin @axelolin.bsky.social · 23/02/2025

As an update, I think the account has now been wiped, but there is plenty of evidence of previous posts online. Obviously, that doesn't matter. Considering Musks previous meddling with German politics and the fact this happened on the day of the German election, it is clear this was no accident.

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Axel Olin @axelolin.bsky.social · 23/02/2025

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Axel Olin @axelolin.bsky.social · 05/02/2025

Nice recipe! What type of tequila are you using?

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Nikolai Slavov @slavov-n.bsky.social · 31/01/2025

This rate of validation suggests that antibodies should be considered non-specific until proven otherwise: 357 validated out of 1,124 tested. .

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Axel Olin @axelolin.bsky.social · 23/01/2025

This guy is a xenophobic right-wing lunatic, unfortunately. There are plenty of other reasons to be proud though! :)

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Jochen Schwenk @jochwenk.bsky.social · 15/01/2025

Here's our latest work on proteome profiling of self-sampled dried blood spots to gain insights into the heterogeneity of the immune response against infections and vaccinations. We enrolled random citizens by postal mail to learn more about the molecular effects beyond those seeking medical care.

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allen institute @alleninstitute.org · 06/01/2025

🩸🔬 Introducing #CryoSCAPE, a groundbreaking technique that keeps blood cells alive in deep freeze. This innovation promises to expand the reach of cutting-edge single-cell technologies to rural or underserved populations. ✨ 🧵 #SingleCellTech #RNAseq

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Camila Consiglio @consigliocr.bsky.social · 03/01/2025

‼️‼️ Last few days to apply to join us as a #PostDoc in #SystemsImmunology and explore mechanisms of #SexDifferences in #Human #Immunity at Lund University in #Sweden More info on how to apply below (please RT)

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Axel Olin @axelolin.bsky.social · 23/12/2024

Trump just casually hinting that territories of allied countries might have to be incorporated into the United States because of 'national security'.

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Axel Olin @axelolin.bsky.social · 16/12/2024

I remember thinking about which protein name has the longest fully expanded name. The longest I came up with then was TBK1, equaling: Tumor necrosis factor receptor-associated factor family member-associated nuclear factor kappa-light-chain-enhancer of activated B cells activator-binding kinase 1

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Axel Olin @axelolin.bsky.social · 11/12/2024

Very cool study! I'm looking forward to seeing results for other pathogens, as you hint at below. Have you only tried this with adult mice so far? I would be interested to see how this phenomenon relates to age.

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Michael Fischbach @mfgrp.bsky.social · 11/12/2024

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55

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Tomàs Montserrat Ayuso @tmontsay.bsky.social · 03/12/2024

Not checking nuclear markers like MALAT1 or intronic reads in your scRNA-seq data?🚨 We show their power to flag low-quality cells—even in top public datasets. It’s time to prioritize better QC for cleaner, more reliable genomics research! Read more: bmcgenomics.biomedcentral.com/articles/10.... 1/8

bmcgenomics.biomedcentral.com

High content of nuclei-free low-quality cells in reference single-cell atlases: a call for more stringent quality control using nuclear fraction - BMC Genomics

The advent of droplet-based single-cell RNA-sequencing (scRNA-seq) has dramatically increased data throughput, enabling the release of a diverse array of tissue cell atlases to the public. However, we...

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Roland Hatzenpichler @environmicrobio.bsky.social · 30/11/2024

I demand that every study that uses fecal samples be renamed from a "gut microbiome" to "fecal microbiome" study, including in the title. Thus, researchers would have to focus on good study design rather than sensationalism. Stool samples are NOT representative for the gut.

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Jessica Nordlund @jessie-no.bsky.social · 28/11/2024

I am excited about Pixelgen Technologies molecular pixelation assay for single cell spatial proteomics. They have a new new tech note out in collab with #illumina www.illumina.com/content/dam/...

illumina.com

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Axel Olin @axelolin.bsky.social · 28/11/2024

Preprint servers enabling these types of solutions as an alternative to PDFs would be a significant first step. The issue is that if the big publishing houses don't adopt it, it will essentially eliminate any chances of publishing it.

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Axel Olin @axelolin.bsky.social · 28/11/2024

These types of solutions look very interesting for scientific publishing: curvenote.com Producing manuscripts (especially figures) suck due to the poor software available. Reading is an equally terrible experience, having to zoom in on figures and scroll up and down to look at references.

curvenote.com

Curvenote | Scientific publishing infrastructure

Curvenote develops next-generation publishing infrastructure and writing tools to support open, reproducible research. A beautiful writing tool designed for technical writing, connected to Jupyter. Wr...

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Axel Olin @axelolin.bsky.social · 28/11/2024

I think issues arise when institutional/job/grant review boards actually DO care about them and use their publication/citations as a metric for scientific productivity. When such AI use is blatant, it should be considered scientific misconduct, almost on the level of fabricating results.

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John Tsang @tsanglab.bsky.social · 17/11/2024

I created a starter pack for systems immunology - let me know if you would like to be added. Excited to be here on @bsky.app go.bsky.app/PjH2Fuj

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Axel Olin @axelolin.bsky.social · 24/11/2024

This is great! Could you add me please? 😊

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Axel Olin @axelolin.bsky.social · 24/11/2024

Based on the figures, it is a bit unclear whether the statistic is papers authored per researcher or simply the total number of published papers divided by the total number of active researchers independent of authorship. Is it clear from the text?

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Axel Olin @axelolin.bsky.social · 23/11/2024

Does anyone have experience in using AI tools dedicated to the research grant writing process and found them useful? I've found a few, but they still seem a bit too general and rudimentary.

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Axel Olin @axelolin.bsky.social · 22/11/2024

Data on the effects of preanalytical factors on single-cell omics are severely lacking (as indicated by the lack of refs in this paper). It is great that this is being investigated for ATACseq and that methods to mitigate it are developed.

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Axel Olin @axelolin.bsky.social · 21/11/2024

My guess would be to emphasize that we're talking about interactive electronic maps rather than paper maps and to convey some idea of user-friendliness. I get slightly different associations for 'maps' and 'Google Maps', but maybe it's just me.

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Axel Olin @axelolin.bsky.social · 21/11/2024

I think it is because, for an analogy to be helpful, it has to be relatable to people. More people have used Google Maps than Open Street Maps, regardless of any differences in quality or ethical considerations between these services.

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Axel Olin @axelolin.bsky.social · 20/11/2024

I've seen a range of medicine and biomedicine-related starter packs, but has anyone seen some that are more medtech- or medical engineering-related?

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Axel Olin @axelolin.bsky.social · 18/11/2024

Yes, especially since the number of experimental variables that might affect antibody binding is too high to evaluate exhaustively anyway. It would be great if journals/editors started requiring antibody validation for antibodies that are critical for the conclusions in the paper.

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Axel Olin @axelolin.bsky.social · 18/11/2024

As someone who has worked extensively with antibodies, I agree these initiatives are crucial. It's scary to imagine that we might only see the tip of the iceberg. Studying the effects of fluorescent tagging and tissue fixation on antibody binding would also be very interesting.

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Axel Olin @axelolin.bsky.social · 15/11/2024

This is a great resource Rod! Could you please add me as well?

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Axel Olin @axelolin.bsky.social · 14/11/2024

Did you also read The Road? I liked it almost as much.

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Axel Olin @axelolin.bsky.social · 13/11/2024

Blood Meridian by Cormac McCarthy impressed me.

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Axel Olin @axelolin.bsky.social · 12/11/2024

Introductory post! I'm an immunologist who recently transitioned into developing engineering solutions for clinical microsampling. My main interests are population studies in human systems immunology and ways to simplify them. If this interests you, give me a follow or send me a message!

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