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Audald Lloret-Villas

@audald.bsky.social
1.4K followers 492 following 44 posts

Postdoc - computational, evolutionary and conservation genomics @ the Globe Institute (University of Copenhagen) - 🦜👨🏻‍💻🧬 One lives only to make blunders.

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Reposted by Audald Lloret-Villas
Physalia-courses@ONLINE @physaliacourses.bsky.social · 14/09/2026
🧬 Advanced Conservation Genomics | Online, 28 Sept–1 Oct Only a few seats left! Explore effective population size, genetic load, SNP panels, population assignment, hybrid detection & genomics for conservation policy. www.physalia-courses.org/courses-work... #ConservationGenomics
physalia-courses.org
Advanced Conservation Genomics
Dates ONLINE, 28 September -1 October 2026 To foster international participation, this course will be held online
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Hernán E. Morales @hernmoral.bsky.social · 28/08/2026
Our teams had a great time at the 7th European Conservation Genetics Meeting in Antwerp, contributing 4 talks and 3 posters. Thanks to the organizers for a fantastic meeting! #ConsGenMeeting2026
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Audald Lloret-Villas @audald.bsky.social · 26/08/2026
@katarinastuart.bsky.social :)
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Jente Ottenburghs | Avian Hybrids @jenteo.bsky.social · 26/08/2026
New story on the Avian Hybrids blog! Parallel selection in the native and invasive range of the Common Starling avianhybrids.wordpress.com/2026/08/26/p... Based on the Molecular Ecology study of Katarina Stuart and her colleagues | #ornithology
avianhybrids.wordpress.com
Parallel selection in the native and invasive range of the Common Starling
Recent study highlights the importance of a historical baseline.
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Audald Lloret-Villas @audald.bsky.social · 06/08/2026
If it wasn't enough struggle to describe "haplotype", there you go: diplotype!
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Audald Lloret-Villas @audald.bsky.social · 02/07/2026
Thank you very much Andrew :) Our group will find this tremendously interesting.
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Andrew Carroll @acarroll.bsky.social · 02/07/2026
OK, that was indeed interesting. BWA MEM3 is also very fast. MiniBWA is a median of 40% faster than BWA MEM3 and faster in 85% of genomes, with the smallest of genomes favoring BWA MEM3. Thanks for the suggestion. BWA MEM3 is great work as well.
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Molecular Biology and Evolution @molbioevol.bsky.social · 02/07/2026
The Mauritius kestrel has experienced a tough ride - Xuejing Wang will be presenting his MBE article on this topic at the SMBE meeting, drop by if you're interested in popgen. 📋 Open Symposium 10a 🗓️ July 2, 10:30 am Read the paper here 👉 doi.org/10.1093/molbev/msag070 #SMBE2026 #societyjournal
doi.org
Genomic erosion across avian lineages in the context of their evolutionary history
Abstract. Loss of genetic diversity threatens species survival, yet its dynamics and impacts can vary widely across species depending on their evolutionary
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Audald Lloret-Villas @audald.bsky.social · 02/07/2026
Such a useful test for the whole community, thank you. Did you manage to test bwa-mem3 in this comparison? bsky.app/profile/nils...
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Hernán E. Morales @hernmoral.bsky.social · 01/07/2026
Just in time for #SMBE2026, our new preprint is out: using 130 genomes spanning ~200 years, fitness data and simulations, we show that conservation rescued the Mauritius kestrel from extinction, but not from genomic erosion. 🧵 www.biorxiv.org/content/10.6... #popgen #consgen #conservation
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Audald Lloret-Villas @audald.bsky.social · 30/06/2026
Stop by - I might try to link hatch rate in Mauritius parakeets 🦜 with HC Andersen' "den grimme ælling" 🐣 #SMBE2026
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Audald Lloret-Villas @audald.bsky.social · 29/06/2026
That's really annoying... 🫤
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Audald Lloret-Villas @audald.bsky.social · 29/06/2026
There might be a second wifi option, whose password might or might not be "tivolihotel"
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bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 29/06/2026
Conservation rescued the Mauritius kestrel from extinction but not from genomic erosion www.biorxiv.org/content/10.64898/20…
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Hernán E. Morales @hernmoral.bsky.social · 28/06/2026
It is finally time for #SMBE2026! Our team will be presenting 10 contributions (3 talks and 7 posters) spanning conservation genomics, temporal genomics, genomic erosion, AI, genome editing, and evolutionary forecasting. Here's where you can find us. See the 🧵 below for all the details.
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Society for Molecular Biology and Evolution @official-smbe.bsky.social · 28/06/2026
The Workshop on Future Directions in Vertebrate Genomics Research is already running, presenting activities associated with the completion of Phase I of @vertebrategenomes.bsky.social #SMBE2026
Woekshop on Future Directions in Vertebrate Genomics Research, SMBE 2026
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Audald Lloret-Villas @audald.bsky.social · 27/06/2026
Yes, what a lovely day! Waiting now the week to start 🚀
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Audald Lloret-Villas @audald.bsky.social · 24/06/2026
🥵 20-24 expected here throughout the week
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Audald Lloret-Villas @audald.bsky.social · 24/06/2026
We are only a few days away from #SMBE2026. Who is planning on coming to the climate haven of Copenhagen? Say 🙋🏾 and bring your swimsuits!
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Tom Mathers @tom-mathers.bsky.social · 16/05/2025
Struggling to find the tiny microchromosomes in draft bird genome assemblies? Our new #preprint introducing MicroFinder can help: www.biorxiv.org/content/10.1... 🧵 below (1/n) @sangerinstitute.bsky.social
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Wellcome Sanger Institute @sangerinstitute.bsky.social · 22/05/2026
Scientists have developed a new tool that makes bird genomes faster and easier to assemble — including tiny pieces of DNA that are usually missed. 🐦‍⬛ The new tool, known as MicroFinder, could help improve research into bird evolution, biodiversity and conservation. 👇 bit.ly/4wG023C
sanger.ac.uk
New tool helps accurately assemble notoriously difficult bird genomes
MicroFinder can be used to assemble bird genomes much quicker and more accurately than ever before.
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Anna Hewett @annamhew.bsky.social · 10/06/2026
📣 New paper out in ProcB📣 ... and we're on the cover! (Perks of having a beautiful study species) Find it here: royalsocietypublishing.org/rspb/article...
royalsocietypublishing.org
Inbreeding depression in morphological and growth traits of wild barn owls (Tyto alba)
Abstract. Despite its detrimental effects, inbreeding depression in wild populations is relatively under-explored. Here, we use whole-genome sequence data
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Hui Zhen Tan @huizhentan.bsky.social · 03/06/2026
New study 🧬 Inbreeding depression is a concern in small populations, and evaluating its genomic proxies is important for #ConservationGenomics. In hihi, genome-wide homozygosity best predicts lifetime reproductive success, compared to genetic load and FROH. Publication: doi.org/10.1111/eva.... 1/3
doi.org
Genome‐Wide Homozygosity Predicts Inbreeding Depression in the Hihi/Stitchbird (Notiomystis cincta) Better Than Realised Load
Population declines result in increasingly small populations, which often experience an increase in inbreeding. Inbreeding may be negatively associated with fitness traits like survival and reproduct...
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Audald Lloret-Villas @audald.bsky.social · 29/04/2026
We dONT know yet - any fancy Swiss bird genomes we could swap?
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Genome Biology and Evolution @genomebiolevol.bsky.social · 29/04/2026
@rsbiello.bsky.social et al. present the first whole-genome analysis of Mediterranean fin whales, showing that although these form a distinct genetic cluster, they are not fully isolated from North Atlantic populations. 📷 Danny Kessler 🔗 doi.org/10.1093/gbe/evag084 #genome #evolution #popgen
GBE | One Sea, Different Whales: Genomics Sheds Light on a Small Population of Fin Whales

Photo: Fin whale (Balaenoptera physalus) swimming in the Mediterranean Sea; by Danny Kessler - dannykesslerphotography.com
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Audald Lloret-Villas @audald.bsky.social · 29/04/2026
A couple of (belted?) Galloway cows enjoying the first spring days in Utterslev Mose, the outskirts of Copenhagen.
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Audald Lloret-Villas @audald.bsky.social · 28/04/2026
Some botanical gardens happen to use poison dart frogs to keep insect plagues under control. Interestingly, such frogs are not poisonous in captivity, as they lack the alkaloids they would naturally get from their diet. This is a blurry Epipedobates anthonyi in the Botanisk Have in Copenhagen.
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European Commission @ec.europa.eu · 09/04/2026
Big opportunities for researchers 🌍 We are investing nearly €400 million to help researchers share their work and collaborate with the best scientific teams across the EU. The 2026 Marie Skłodowska-Curie Actions Postdoctoral Fellowships are now open. More: link.europa.eu/PNxpxw
Graphic announcing the MSCA Postdoctoral Fellowships 2026 call. It shows the opening date (9 April 2026), closing date (9 September 2026), and a budget of €399.05 million. The design features scientific visuals such as cells, a leaf, and lab elements on a dark background, with the European Commission logo at the bottom.
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AaRC @aarc-community.bsky.social · 11/04/2026
Just around the corner. Last few days to sign up for the free workshop on relatedness with @jolijnerven.bsky.social!
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Jente Ottenburghs | Avian Hybrids @jenteo.bsky.social · 25/03/2026
New story on the Avian Hybrids blog! Phylogenomic analyses reveal an X-linked speciation supergene in placental mammals avianhybrids.wordpress.com/2026/03/25/p... Based on the Nature paper by Nicole Foley and her colleagues | Focusing on mammals, with a bit of #ornithology
avianhybrids.wordpress.com
Phylogenomic analyses reveal an X-linked speciation supergene in placental mammals
Could a similar genomic region exist in birds?
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Anna Brüniche-Olsen @annabruniche.bsky.social · 04/03/2026
Great write up of our study showing that both extrinsic factors (e.g. habitat availability) and intrinsic traits (e.g. body mass and diet) play important roles in shaping patterns of genomic diversity in birds 🦜 🧬 🌏 #consgen #popgen
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Ewan Birney @ewanbirney.bsky.social · 26/02/2026
Are you a computational postdoc or even in the last year of your PhD and you want to set up your own lab? Want to work in one of the most multi-disciplinary and multi-national institutions in the world? Want to be a leader in understanding biology - molecules up? Apply below!
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Audald Lloret-Villas @audald.bsky.social · 12/02/2026
Snakemake, you are too polite. The answer to "invalid syntax. Perhaps you forgot a comma?" is always YES 🤪
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Society for Molecular Biology and Evolution @official-smbe.bsky.social · 28/01/2026
We have less than a week to go before the deadline for abstract submission and award applications for SMBE 2026 in Copenhagen. Check the conference website for details on the programme, symposia, and awards: smbe2026.org #SMBE2026
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Clàudia Fontserè @claudiafontsere.bsky.social · 23/01/2026
Just a few more days to submit abstracts to #SMBE2026 in beautiful Copenhagen. 🗓️Deadline 3nd February We are organizing S01: Evolutionary-informed management of vulnerable populations in a rapidly changing world. Hope to see many of you there!
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Mike Wiser @drmikewiser.bsky.social · 23/12/2025
One of the most pleasant surprises of the past 20 years was the transformation of Wikipedia into arguably the most reliable general information source freely accessible to the public. It’s not perfect — I’ve certainly seen errors — but it’s kind of shockingly good. One might consider a donation.
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Emilio Mármol Sánchez @marmole6.bsky.social · 14/11/2025
🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social www.cell.com/cell/fulltex... If you want to know more, read the 🧵 below:
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Audald Lloret-Villas @audald.bsky.social · 08/11/2025
"Franklin was an equal member in a group of four scientists [...] recognized by her colleagues as such, although that acknowledgement was both belated and understated [...] deserves to be remembered not as the victim of the double helix, but as an equal contributor to the solution of the structure."
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Audald Lloret-Villas @audald.bsky.social · 08/11/2025
"it was not a case of them stealing the King’s group’s data and then, voila, those data gave them the structure of DNA. Instead, they solved the structure through their own iterative approach and then used the King’s data — without permission — to confirm it."
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Physalia-courses@ONLINE @physaliacourses.bsky.social · 07/11/2025
What a course!🧬🦣 Thanks to this amazing team of instructors @claudiafontsere.bsky.social @jazminrm.bsky.social & @hernmoral.bsky.social for delivering such a great first edition of the #Museomics course. Thanks to everyone who has joined us this week and good luck with your data!💯
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Katarina Stuart @katarinastuart.bsky.social · 22/10/2025
New Zealand’s invasive starlings on the cover of Molecular Ecology! 🐦🧬 This collaborative project unpacks the invasion history of starlings in Aotearoa New Zealand, combining population genomics with historical records of human-mediated translocations. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
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Population and Statistical Genetics Group at UCPH @popgendk.bsky.social · 22/10/2025
Our monthly #EPIC seminars are back! 🎉 This month, Thomas Bøggild kicked things off with a fascinating talk on stopped recombination in new sex chromosomes, and @audald.bsky.social followed with great insights into recombination maps and imputation in #PopGen studies. See you next month!
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Sabhrina Aninta @sagitaninta.bsky.social · 22/10/2025
Our Q&A article on inbreeding for conservation is out in BMC Biology! We discuss some important key concepts related to inbreeding in the light of new genomic tools and what it means for conservation when we want to improve species survival. #consgen bmcbiol.biomedcentral.com/articles/10....
bmcbiol.biomedcentral.com
Q&A: inbreeding and its implications for conservation - BMC Biology
Inbreeding depression plays a role in the decline, endangerment, and extinction of small populations, and thus inbreeding has received much attention in conservation biology. The term inbreeding is us...
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Lluis Montoliu @lluismontoliu.bsky.social · 24/08/2025
Este verano visitamos Cambridge, con su universidad y centros de investigación referentes en biología molecular. Donde trabajó Fred Sanger, ganador de 2 premios Nobel de Química. Un investigador singular e irrepetible. Te lo explico en mi blog @naukas.bsky.social montoliu.naukas.com/2025/08/24/u...
montoliu.naukas.com
Un tipo llamado Fred Sanger - Gen-Ética
Este verano hemos pasado unos días en Cambridge (Reino Unido), ciudad universitaria por excelencia y sede de prestigiosos e históricos centros de investigación. Estos centros convierten a Cambridge en...
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Audald Lloret-Villas @audald.bsky.social · 04/10/2025
💡 Bonus: Open Snakemake pipelines for both simulation and imputation are provided: - github.com/vibaotram/si... - github.com/vibaotram/im... Feel free to test and optimize imputation strategies for your own datasets before committing to large-scale LCS projects.
github.com
GitHub - vibaotram/simulation
Contribute to vibaotram/simulation development by creating an account on GitHub.
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Audald Lloret-Villas @audald.bsky.social · 04/10/2025
💥 Downstream impact: - PopGen analyses (relatedness, population structure) were congruent with imputation accuracy and depend on genetic relatedness. - Inbreeding coefficient estimates were more sensitive to imputation. - Demographic analysis on imputed data showed similar results across the tools.
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Audald Lloret-Villas @audald.bsky.social · 04/10/2025
🔑 Choosing your imputation tool: - All tools worked well in highly related populations. - Accuracy varied in populations with low relatedness, but GLIMPSE2 & QUILT2 generally outperformed the other tools. - STITCH is useful when no reference panel exists but results in some missing data.
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Audald Lloret-Villas @audald.bsky.social · 04/10/2025
👩🏻‍💻 We tested 5️⃣ imputation methods (GLIMPSE2, GeneImp, QUILT2, STITCH, Beagle5.4), simulated realistic populations with different genetic structures, and applied the methods to data from 283 wild hihi (stitchbird) 🧬.
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Audald Lloret-Villas @audald.bsky.social · 04/10/2025
We explored that in this new study in Molecular Ecology Resources 🔎 onlinelibrary.wiley.com/doi/10.1111/... @vbtram.bsky.social @huizhentan.bsky.social @katarinastuart.bsky.social @annasanture.bsky.social
onlinelibrary.wiley.com
Assessing Genotype Imputation Methods for Low‐Coverage Sequencing Data in Populations With Differing Relatedness and Inbreeding Levels
Low-coverage sequencing (LCS) followed by genotype imputation has become a cost-efficient approach for obtaining whole-genome SNPs. Several imputation methods for LCS data have been developed over th....
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Audald Lloret-Villas @audald.bsky.social · 04/10/2025
Low-coverage sequencing (LCS) + genotype imputation is a cost-effective approach to genotype hundreds of samples at a full-genome level. But how do different imputation tools perform across populations with varying relatedness and inbreeding?
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