iiinova — where your digital self keeps evolving

Reposted by Alexey Soshnev

Alex Wenzel @alexwenzel.bsky.social · 22/09/2026

For every one of these men who get a dramatic front page story, there are 25-50 postdocs who leave the country much less voluntarily.

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Alexey Soshnev @asoshnev.bsky.social · 27/07/2026

Out on bioRxiv - chemogenetic activation of VTA astrocytes switches pro- to anti-addictive behavior dependent on prior drug exposure - via @mattjwanat.bsky.social and our collaborators at UT Health

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Reposted by Alexey Soshnev

Craig Kaplan @triggerloop.bsky.social · 29/06/2026

Please email me if you are interested in this postdoctoral position on gene expression and human disease mechanisms and apply here with a cover letter and CV: 2/2 (reskeets/reposts appreciated!!) cfopitt.taleo.net/careersectio...

cfopitt.taleo.net

Post Doctoral Associate

Click the link provided to see the complete job description.

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Alexey Soshnev @asoshnev.bsky.social · 23/05/2026

As far as I understand the issue is not with the translation per se but rather with the expense reports - it was a state funded contract and the state now says the receipts don't match up... As they say in Russia "был бы человек, а статья найдется" - "we can find an indictment for anyone"

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Alexey Soshnev @asoshnev.bsky.social · 23/05/2026

3/n - Aristotle is just a pretext. Although plot of the Name of the Rose definitely comes to mind 😄

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Alexey Soshnev @asoshnev.bsky.social · 23/05/2026

2/n - with budgets in the billions (think all US research universities combined) plus extremely lucrative properties inherited from USSR (think palaces and mansions downtown Moscow and St Petersburg). Controlling that is a good business and several clans have been fighting over it for decades.

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Alexey Soshnev @asoshnev.bsky.social · 23/05/2026

(1/n) The institute in question has been part of power struggle in Russian academy of sciences (RAS) for decades, this is just one more episode...unlike NAS in the US which is more of a club for select few, RAS is basically running all fundamental (and applied) research in the country -

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Alexey Soshnev @asoshnev.bsky.social · 28/04/2026

This is crazy cool. Will start the grad molbio lecture today with these.

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Alexey Soshnev @asoshnev.bsky.social · 23/04/2026

Lev Tolstoy is "Fat Lion". Pushkin is "Gunman". Lermontov is hard, I heard it's a derivative of a Perisan but don't have a source. Karamzin is definitely turkic, "black prince" or smth like that. Griboedov is the best - "Mushroom eater". Brodsky is "Wanderer" (actually fits pretty well)...

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Alexey Soshnev @asoshnev.bsky.social · 23/04/2026

Maxim Gorky ("bitter") is a pen name. He is actually Aleksei Peshkov (not sure the origin but peshka (пешка) из "pawn" in chess

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Reposted by Alexey Soshnev

kenofseattle @kenofseattle.bsky.social · 02/04/2026

"Biggest scam in modern political history."

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Alexey Soshnev @asoshnev.bsky.social · 03/04/2026

Aged like malk. Now with vitamin R...

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Reposted by Alexey Soshnev

Jeremy Berg @jeremymberg.bsky.social · 30/03/2026

Watch Director Bhattacharya's performance at CPAC really got to me. I chose to share some of my observations with him. Hold on... 1/11

media.tenor.com

Here We Go Sherman Bell GIF

ALT: Here We Go Sherman Bell GIF

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Reposted by Alexey Soshnev

The Lewis Lab @peterlewislab.bsky.social · 22/03/2026

Happy 30th birthday to this paper published March 22, 1996, one of the studies that moved chromatin biology from correlation toward mechanism. Brownell et al. linked a transcription-associated Tetrahymena HAT to yeast Gcn5p, providing a biochemical link for chromatin modification to gene activation.

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Alexey Soshnev @asoshnev.bsky.social · 29/01/2026

I had a pair of skis of "mladost" brand back in a day: Если хочешь сделать гадость, подари мне лыжи "Младость". No clue why I still remember this... Random post gets a random comment!

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Alexey Soshnev @asoshnev.bsky.social · 25/11/2025

Grad school application portals that require you to make an account to submit a reference letter should not exist /rant

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Reposted by Alexey Soshnev

Mikhail Spivakov @mspivakov.bsky.social · 25/11/2025

I'm guest-editing a collection on "Enhancer-promoter interactions" at Genome Biology. Please send us your exciting stories! link.springer.com/collections/...

link.springer.com

Enhancer-promoter interactions

Genome Biology is calling for submissions to our Collection on enhancer-promoter interactions. Enhancer–promoter interactions are central to the regulation ...

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Alexey Soshnev @asoshnev.bsky.social · 13/08/2025

Don't post often but this is a good occasion: we wrote a huge review about mechanisms that preserve chromatin fidelity, and how its progressive degradation occurs in disease. Inspired by #oncohistones but mostly *not* about that. Bonus, snuck Horace into the title! academic.oup.com/narmolmed/ar...

academic.oup.com

Aere perennius: how chromatin fidelity is maintained and lost in disease

Abstract. Multicellular organisms arise from a single genome template in the zygote, necessitating the cells of the developing embryo to up- and downregula

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Reposted by Alexey Soshnev

Adrian Bracken @adrianbracken.bsky.social · 21/05/2025

Check out this 🧵 from @eimearlagan.bsky.social on our new Molecular Cell @cp-molcell.bsky.social paper! We show how the H3K27M Oncohistone reprograms chromatin in DMG, creating a specific dependency on CBX4/PCGF4-containing forms of cPRC1 👇

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Alexey Soshnev @asoshnev.bsky.social · 04/03/2025

Not that I wont be thrilled to grow a shaggy mouse...

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Reposted by Alexey Soshnev

The Lewis Lab @peterlewislab.bsky.social · 03/11/2024

The HuSH complex silences retrotransposable elements. We identify HuSH2, centered on TASOR2, targeting KRAB-ZNFs and interferon genes, balancing retrotransposon silencing and immune regulation. www.nature.com/articles/s41...

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