iiinova — where your digital self keeps evolving

Reposted by Alexey Soshnev

Alex Wenzel @alexwenzel.bsky.social · 22/09/2026

For every one of these men who get a dramatic front page story, there are 25-50 postdocs who leave the country much less voluntarily.

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Alexey Soshnev @asoshnev.bsky.social · 27/07/2026

Out on bioRxiv - chemogenetic activation of VTA astrocytes switches pro- to anti-addictive behavior dependent on prior drug exposure - via @mattjwanat.bsky.social and our collaborators at UT Health

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Reposted by Alexey Soshnev

Craig Kaplan @triggerloop.bsky.social · 29/06/2026

Please email me if you are interested in this postdoctoral position on gene expression and human disease mechanisms and apply here with a cover letter and CV: 2/2 (reskeets/reposts appreciated!!) cfopitt.taleo.net/careersectio...

cfopitt.taleo.net

Post Doctoral Associate

Click the link provided to see the complete job description.

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Reposted by Alexey Soshnev

kenofseattle @kenofseattle.bsky.social · 02/04/2026

"Biggest scam in modern political history."

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Reposted by Alexey Soshnev

Jeremy Berg @jeremymberg.bsky.social · 30/03/2026

Watch Director Bhattacharya's performance at CPAC really got to me. I chose to share some of my observations with him. Hold on... 1/11

media.tenor.com

Here We Go Sherman Bell GIF

ALT: Here We Go Sherman Bell GIF

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The Lewis Lab @peterlewislab.bsky.social · 22/03/2026

Happy 30th birthday to this paper published March 22, 1996, one of the studies that moved chromatin biology from correlation toward mechanism. Brownell et al. linked a transcription-associated Tetrahymena HAT to yeast Gcn5p, providing a biochemical link for chromatin modification to gene activation.

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Alexey Soshnev @asoshnev.bsky.social · 25/11/2025

Grad school application portals that require you to make an account to submit a reference letter should not exist /rant

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Reposted by Alexey Soshnev

Mikhail Spivakov @mspivakov.bsky.social · 25/11/2025

I'm guest-editing a collection on "Enhancer-promoter interactions" at Genome Biology. Please send us your exciting stories! link.springer.com/collections/...

link.springer.com

Enhancer-promoter interactions

Genome Biology is calling for submissions to our Collection on enhancer-promoter interactions. Enhancer–promoter interactions are central to the regulation ...

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Alexey Soshnev @asoshnev.bsky.social · 13/08/2025

Don't post often but this is a good occasion: we wrote a huge review about mechanisms that preserve chromatin fidelity, and how its progressive degradation occurs in disease. Inspired by #oncohistones but mostly *not* about that. Bonus, snuck Horace into the title! academic.oup.com/narmolmed/ar...

academic.oup.com

Aere perennius: how chromatin fidelity is maintained and lost in disease

Abstract. Multicellular organisms arise from a single genome template in the zygote, necessitating the cells of the developing embryo to up- and downregula

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Reposted by Alexey Soshnev

Adrian Bracken @adrianbracken.bsky.social · 21/05/2025

Check out this 🧵 from @eimearlagan.bsky.social on our new Molecular Cell @cp-molcell.bsky.social paper! We show how the H3K27M Oncohistone reprograms chromatin in DMG, creating a specific dependency on CBX4/PCGF4-containing forms of cPRC1 👇

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Alexey Soshnev @asoshnev.bsky.social · 04/03/2025

Not that I wont be thrilled to grow a shaggy mouse...

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Reposted by Alexey Soshnev

The Lewis Lab @peterlewislab.bsky.social · 03/11/2024

The HuSH complex silences retrotransposable elements. We identify HuSH2, centered on TASOR2, targeting KRAB-ZNFs and interferon genes, balancing retrotransposon silencing and immune regulation. www.nature.com/articles/s41...

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