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Aleksandra Skrajna

@askrajna.bsky.social
1.4K followers 93 following 18 posts

Asst Prof at UC Santa Cruz, studying histones and chromatin, using CryoEM and proteomics. New mom. Dog lover. Athlete. University of Warsaw -> Polish Academy of Sciences -> UNC Chapel Hill -> UCSC

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Reposted by Aleksandra Skrajna
Alex Guseman @alexguseman.bsky.social · 02/04/2025
Welp, i got halfway through the RPPR and then received notice the MOSAIC program, and thus my MOSAIC R00 has been terminated. Thank you to those who made this program. Thank you to the other #NIHMOSAIC fellows have supported me through my faculty journey and continue to inspire me.
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Reposted by Aleksandra Skrajna
arXiv stat.ME Methodology @statme-bot.bsky.social · 31/03/2025
John Mellnik, Jack Scannell: Tripartite models for estimating the value of drug candidates and decision tools arxiv.org/abs/2503.22117 arxiv.org/pdf/2503.22117 arxiv.org/html/2503.22117
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Aleksandra Skrajna @askrajna.bsky.social · 29/03/2025
The Department of Chemistry and Biochemistry at UC Santa Cruz is looking for a General Chemistry Assistant Teaching Professor - recruit.ucsc.edu/JPF01884 We truly value teaching and mentoring and looking for like minded applicants. Please apply, share, and recommend people who might be interested.
recruit.ucsc.edu
General Chemistry Assistant Teaching Professor (Initial Review Date: May 14, 2025)
University of California, Santa Cruz is hiring. Apply now!
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Reposted by Aleksandra Skrajna
Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 21/03/2025
Opinion piece in the @scsentinel.bsky.social by me, @carpenterlab.bsky.social and Carol Greider: Trump is turning off the lights on biomedical research: Why it matters for Santa Cruz www.santacruzsentinel.com/2025/03/20/g...
santacruzsentinel.com
Guest Commentary | Trump is turning off the lights on biomedical research: Why it matters for Santa Cruz
“These cuts aren’t just about UCSC; they’re about Santa Cruz,” writes Needhi Bhalla, Susan Carpenter and Carol Greider in a Guest Commentary. “This crucial NIH support fuels our l…
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Aleksandra Skrajna @askrajna.bsky.social · 20/03/2025
My most challenging postdoctoral project, where we show that histones but not nucleosomes are polyubiqutinated by the APC/C for a potential proteasomal degradation was just published in @naturecomms.bsky.social 🎉 www.nature.com/articles/s41... Big shout-out to all co-authors!!!
nature.com
APC/C-mediated ubiquitylation of extranucleosomal histone complexes lacking canonical degrons - Nature Communications
The APC/C ubiquitylates histones to regulate gene expression in pluripotent cells. Here, the authors pair cryo-EM and biochemical and biophysical assays to show that instead of modifying nucleosome-in...
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Reposted by Aleksandra Skrajna
UC Santa Cruz Science @ucscscience.bsky.social · 05/03/2025
UC Santa Cruz researcher Upasna Shrarma and team uncover four novel genes essential for male fertility in mice, contributing to her broader federally funded research on how a father’s life experiences & environment influence the health of his children.🔬👨‍🍼 #ScienceNews news.ucsc.edu/2025/03/trna...
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Aleksandra Skrajna @askrajna.bsky.social · 11/03/2025
Really nice infographic of the cost of federally sponsored research. www.cogr.edu/sites/defaul...
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Aleksandra Skrajna @askrajna.bsky.social · 08/03/2025
www.kazu.org/kazu-news/20...
kazu.org
UC Santa Cruz professors and students rally for science
Several hundred people rallied in Santa Cruz Friday to support science in the face of significant threats to federal funding. “Stand Up for Science” rallies took place on the UC Santa Cruz main campus...
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Reposted by Aleksandra Skrajna
Angela Andersen @angelaandersen.bsky.social · 04/02/2025
JEDI awards provide input on a manuscript, short grant proposal, or job application to scientists facing unfair, systemic barriers to career progression. Next deadline March 10th - please share & apply! lifescienceeditors.org/apply/
lifescienceeditors.org
JEDI Award - Life Science Editors Foundation
Our Justice, Equity, Diversity and Inclusion (JEDI) awards provide Feedback on Your Scientific Writing from one of our expert volunteers. These awards are offered quarterly to scientists facing unfair...
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Aleksandra Skrajna @askrajna.bsky.social · 09/12/2024
After an exciting year of setting up my lab and life in Santa Cruz I am back on bluesky and hope to interact with y'all more. I'm gearing up towards setting up an arrayed CRISPR screen and wonder what are your favorite companies to work with for guide RNAs. Edit Co, IDT, Horizon?
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Reposted by Aleksandra Skrajna
Needhi Bhalla 💅🏽 @needhibhalla.bsky.social · 04/04/2024
Super useful and eminently readable demystification of writing a successful NIH grant application, written by NIH Program Officers (POs) with LOTS of great guidance:
pnas.org
Elements of successful NIH grant applications | Proceedings of the National Academy of Sciences
Is there a formula for a competitive NIH grant application? The Serenity Prayer may provide one: "Grant me the serenity to accept the things I cann...
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Aleksandra Skrajna @askrajna.bsky.social · 14/02/2024
It's hard to be a new PI and new mom without a daycare (yet). Sending ♥️ to all moms in academia.
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Aleksandra Skrajna @askrajna.bsky.social · 11/02/2024
Happy International Day of Women and Girls in Science!!!
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Aleksandra Skrajna @askrajna.bsky.social · 25/01/2024
Exciting news - my lab is hiring a junior scientist! Please apply if you are interested in learning lots of biochemistry and helping me run the lab. recruit.ucsc.edu/JPF01676
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Aleksandra Skrajna @askrajna.bsky.social · 29/11/2023
Great job opportunity at UNC Chapel Hill for anyone who wants to learn or dive deeper into CryoEM. Josh (core director) is fun to work with and continues to develop new approaches and methods in CryoEM. Therefore this appointment is not just a routine technical work it's actually very creative!
unc.peopleadmin.com
Research Technician
This position will be supporting the Med Admin- Research department and provide technical support for daily operations of the CryoEM Core. The CryoEM Core is a multi-user facility that provide researc...
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Aleksandra Skrajna @askrajna.bsky.social · 14/11/2023
I opened the eggnog season today. A little balm to my heart in these difficult times. Cheers.
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Aleksandra Skrajna @askrajna.bsky.social · 28/10/2023
Yesterday I received a Postdoctoral Award for Research Excellence 🎉 Having my friends and family in the audience was incredibly moving. What a year ?! 1) I got a dream job, 2) I had a baby and now 3) this award. I'm incredibly grateful for everyone who made it possible 😊
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Aleksandra Skrajna @askrajna.bsky.social · 20/10/2023
I'd also add that Alphafold doesn't predict interactions of nucleic acids with proteins, which are the basis of so many biological processes.
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Reposted by Aleksandra Skrajna
Karolin Luger @nucleosomepolice.bsky.social · 19/10/2023
Nice news and views article covering our recent manuscript on bacterial histones. Thanks for covering this! www.nature.com/articles/s41...
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Aleksandra Skrajna @askrajna.bsky.social · 19/10/2023
I'm trying to add my profile photo, I save changes, but it turns black when I go back to home view. Any advice?
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Aleksandra Skrajna @askrajna.bsky.social · 19/10/2023
UNC PARE ceremony is next Friday at 3PM (10/27/23) 🎉 research.unc.edu/2023/10/18/2...
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