Asaf Levy @asaflevylab.bsky.social · 05/10/2026... and the days Fig. 1 of a Science paper is an ugly pairwise sequence alignment !!! 020
Asaf Levy @asaflevylab.bsky.social · 05/10/2026I love the vision at the end of Nagel et al. Science 2002: "the ability of ChR1 to mediate a large light-switched H+ conductance in oocytes holds promise for the use of ChR1 as a tool for measuring and/or manipulating electrical and proton gradients across cell membranes, simply by illumination."science.orgChannelrhodopsin-1: A Light-Gated Proton Channel in Green AlgaePhototaxis and photophobic responses of green algae are mediated by rhodopsins with microbial-type chromophores. We report a complementary DNA sequence in the green alga Chlamydomonas reinhardtiithat ... 151
Reposted by Asaf LevyFlorent Waltz @florentwaltz.bsky.social · 05/10/2026Huge congratulations to all three Nobel Laureates, and especially Peter Hegemann! 👏 His seminal work on the green alga Chlamydomonas 🦠 laid the foundation for optogenetics. Thank you for putting Chlamy in the spotlight! ✨ Proof that groundbreaking discoveries don't always come from animal models! 🔬 023378
Reposted by Asaf LevyInternational Society for Molecular Plant-Microbe Interactions @ismpmi.bsky.social · 01/10/2026Did you miss yesterday's fantastic Legends of IS-MPMI webinar with @jonathandgjones.bsky.social? You can watch the whole thing on our YouTube channel! 👇 youtu.be/yynU5Bu8BRM?...youtu.beRoad to Jeju Webinar by Jonathan Jones. Recognizability and Recognize-ability...YouTube video by IS-MPMI 176
Asaf Levy @asaflevylab.bsky.social · 01/10/2026Correction: the young victim was found dead and I don't know the reason for her death. I assumed she took her life. 000
Asaf Levy @asaflevylab.bsky.social · 01/10/2026It is also highly disturbing that it took my university years to handle the sexual harassment complaint. 100
Asaf Levy @asaflevylab.bsky.social · 01/10/2026en.wikipedia.org/wiki/Karim_A... This guy is now employed as a Directeur de Recherche with the CNRS, situated at Sorbonne University after leaving the Hebrew U. The person he sexually harassed for years until she complained, his student, Johanna Kristina Steinmeyer, committed suicide 6 months ago.en.wikipedia.orgKarim Adiprasito - Wikipedia 130
Asaf Levy @asaflevylab.bsky.social · 30/09/2026In October we are starting year 8 (I think) of the virtual microbiology journal club (on Zoom) with fantatstic speakers, as usual. Most talks are about bacteria. If you (PIs, trainees, anyone interested in science) want to be included in the mailing list - shoot me an email. alevy@mail.huji.ac.il 023
Asaf Levy @asaflevylab.bsky.social · 29/09/2026that was toxic in bacterial cyto/periplasm and in yeast cells. Mutations in the metal binding pocket destroyed its activity. This is another fun collaboration with my friend Dr. Netanel Tzarum. Stay tuned for another paper resulting from this collaboration which will be published in a few days. 000
Asaf Levy @asaflevylab.bsky.social · 29/09/2026We observed that T6SS effectors tend to be longer, more hydrophilic, charged, and ordered, and to reside next to or fused to T6SS genes significantly more than non-T6Es. Common protein domains are depleted from effectors. Another new effector is likely a non-specific metalloprotease 100
Asaf Levy @asaflevylab.bsky.social · 29/09/2026demonstrating a moon-like structural phenotype. You can observe the cell wall unipolar accumulation and degradation in blue. We didn't expect to E. coli looking so weird. We provide predictions of 19,958 T6SS effector candidates in 2,559 T6SS-encoding bacterial genomes. 110
Asaf Levy @asaflevylab.bsky.social · 29/09/2026Chryseobacterium, showed a beautiful phenotype. This toxin, that we named the "moon toxin", targets the peptidoglycan. When expressed in E. coli, it quickly leads to spherical aggregated cells, with inner membrane separation, and gradual peptidoglycan degradation in a unipolar manner, 110
Asaf Levy @asaflevylab.bsky.social · 29/09/2026Our new preprint is out. www.biorxiv.org/content/10.6... We applied an XGBoost algorithm with genomic and biochemical features to detect all T6SS effectors in bacterial genomes. Next, we validated 3 novel effectors that serve as antibacterial or anti-euk toxins. One of the effectors, frombiorxiv.org 162
Asaf Levy @asaflevylab.bsky.social · 28/09/2026I found this paper from 2002 about plant-fungal symbiosis which enables both partners to grow above 45C (!) in geothermal soils in Lassen Volcanic and Yellowstone National Parks. As far as I understand te genetic basis of this thermotolerance is still unknown. www.science.org/doi/10.1126/...science.orgThermotolerance Generated by Plant/Fungal SymbiosisAll plants studied in natural ecosystems are symbiotic with fungi (1), which obtain nutrients while either positively, negatively, or neutrally affecting host fitness (2). Plant adaptation to selectiv... 150
Reposted by Asaf LevyYasin Dagdas @plantophagy.bsky.social · 24/09/2026Congrats @mayavoichek.bsky.social @juliusbrennecke.bsky.social & everyone involved!!! 1243
Reposted by Asaf LevybioRxiv Microbiology @biorxiv-microbiol.bsky.social · 20/09/2026Experimental evolution of root-associated microbial communities www.biorxiv.org/content/10.64898/20… 01010
Reposted by Asaf LevyOmri Finkel עמרי عُمري @finkel-lab.bsky.social · 17/09/2026Michal Breker and I started our labs around the same time. Michal studies Chlamydomonas, and I plant microbiota. We joined forces to see how our bugs interact. This led us down a long and winding road, with 3 amazing PhDs and help from many friends. This is the first product of this collaboration.biorxiv.orgConserved inhibitory mechanisms of root-associated bacteria towards Arabidopsis thaliana and Chlamydomonas reinhardtiiSoil bacteria colonize plants without causing visible disease, yet many suppress host growth. The prevalence and evolutionary reach of this cryptic inhibition are unknown, because phenotyping hundreds... 01411
Asaf Levy @asaflevylab.bsky.social · 16/09/2026Interesting finding by Dianne Newman's group from a few months ago: Elevated antibiotic resistance in soils under drought www.nature.com/articles/s41...nature.comDrought drives elevated antibiotic resistance across soils - Nature MicrobiologyDrought conditions in soil systems lead to elevated concentrations of natural antibiotics, as well as the enrichment of antibiotic-resistant microorganisms, highlighting a link between climate and the... 010
Asaf Levy @asaflevylab.bsky.social · 13/09/2026Nice experimental evolution work from @cascaleslab.bsky.social on the mechanisms by which T6SS is lost during evolution when present with T6SS-immune competing bacteria, compared to its maintenance when competitors are T6SS susceptible. www.cell.com/current-biol...cell.comExperimental evolution reveals genetic routes for adaptive loss of the antibacterial type VI secretion systemTaillefer et al. show that a bacterial type VI secretion system is lost or attenuated during experimental evolution when it provides no competitive advantage but is maintained in the presence of susceptible competitors. T6SS inactivation arises through diverse regulatory and structural mutations, revealing how ecological context shapes antibacterial weapon evolution. 083
Asaf Levy @asaflevylab.bsky.social · 12/09/2026Happy new Jewish year to the Levy lab friends, collaborators, and Reviewers #2 around the world. May the next one will be much more peaceful. (Pic from lab's bday in Palmachim beach 2 days ago). 081
Asaf Levy @asaflevylab.bsky.social · 08/09/2026PISA results are alarming. (Graph from The Economist). 041
Asaf Levy @asaflevylab.bsky.social · 06/09/2026Our friend the @shlezingerlab.bsky.social is hiring! Highly recommended. Working on the fascinating unknown world of mycoviruses. Her 1st postdoc, Marina Campos Rocha, just started her independent academic position. 063
Asaf Levy @asaflevylab.bsky.social · 06/09/2026Cool stuff from the Sorek lab on the functional connection between anti-phage bacterial immunity and plant immunity and the ways to manipulate these. 1st author: Dr. Ohad Roth @soreklab.bsky.social www.biorxiv.org/content/10.6...biorxiv.orgPlant pathogens cleave 2′cADPR to suppress TIR immune signalingSmall molecules produced by TIR (Toll-interleukin-1 receptor) domains are essential for plant immune signaling. A central TIR-derived signal is 2ʹcADPR, a cyclic ADP-ribose (ADPR) molecule that is gen... 080
Asaf Levy @asaflevylab.bsky.social · 06/09/2026journals.plos.org/plospathogen...journals.plos.orgAcidic and alkaline conditions enhance Staphylococcus aureus α-toxin pore formation and cytotoxicityAuthor summary Staphylococcus aureus is a bacterium that can cause severe invasive infections. S. aureus produces many toxins during infection, of which α-toxin (AT) is clinically relevant. AT is a po... 020
Asaf Levy @asaflevylab.bsky.social · 01/09/2026check out Chlorophyll levels in Nasa's satellite eyes.nasa.gov/apps/earth/#...eyes.nasa.govEyes on the Earth - NASA/JPLWelcome to NASA's Eyes, a way for you to learn about your home planet, our solar system, the universe beyond and the spacecraft exploring them. 000
Asaf Levy @asaflevylab.bsky.social · 01/09/2026extreme chlorophyll values are marked in red, source: Matan Hodorov on X. 000
Asaf Levy @asaflevylab.bsky.social · 01/09/2026Pretty amazing ecological effect. Microalgae from the Nile river delta are currently clogging Israel's desalination plants in the Mediterranean, disrupting agriculture in desert which is based on desalinated water. @bejalab.bsky.social 310
Asaf Levy @asaflevylab.bsky.social · 29/08/2026given the monkey business in the field this is news 000
Asaf Levy @asaflevylab.bsky.social · 29/08/2026Amazing achievement to Bonnie Bassler. The medal is shared with the most creative scientists ever lived since the 18th century. 000
Asaf Levy @asaflevylab.bsky.social · 27/08/2026A nice ecological story from Nancy Moran's lab. www.nature.com/articles/s41...nature.comColibactin produced by a honeybee gut symbiont mediates pathogen defence - Nature MicrobiologyA colibactin-producing symbiont in honeybee guts defends against opportunistic pathogens and confers protection. 063
Asaf Levy @asaflevylab.bsky.social · 25/08/2026For nearly 20 years I have used this pic as my FB profile image and already forgot where it was taken by my wife. But today, while hiking with my kids in Aigüestortes i Estany de Sant Maurici National Park (Spain) I found the exact corner and my sons reproduced it. 011
Asaf Levy @asaflevylab.bsky.social · 07/08/2026Elections are on Oct. "A sane government is required" 030
Reposted by Asaf LevyItai Yanai @itaiyanai.bsky.social · 31/07/2026Science funding has still not reached gender equality: "Projects led by male PIs received roughly twice the mean funding compared to female PIs." www.sciencedirect.com/science/arti... 01112
Asaf Levy @asaflevylab.bsky.social · 26/07/2026The pope promotes people to saints after having evidence for their miracles. Pope Leo already canonized 9 people in his short term. Pope Francis: more than 60. And I am thinking about this graph 030
Asaf Levy @asaflevylab.bsky.social · 22/07/2026Take another look at the ranking. The last ones are really poor places (Chad, South Sudan, Lesotho...). Basically where you get sick and die, if I understand correctly. 001
Asaf Levy @asaflevylab.bsky.social · 22/07/2026The only people who ever loved war for long were profiteers, generals, staff officers, and whores. They all had the best and finest time of their lives and most of them made the most money they had ever made. Hemingway, 1936 121
Asaf Levy @asaflevylab.bsky.social · 17/07/2026The year is 2500 Technology enables sampling of the entire ecosystem at atom resolution within milliseconds. Analysis is done using ImageJ 060
Asaf Levy @asaflevylab.bsky.social · 16/07/2026We're recruiting a fungal biologist to our friendly department at the Hebrew University of Jerusalem, Rehovot, Israel. For details contact our chair. Talented non-Israli applicants are welcome to apply. See below. 01215
Asaf Levy @asaflevylab.bsky.social · 10/07/2026A cool work from Ilya and Rotem on the 'damage-associated molecular pattern' that bacteria sense to detect phage attack (DNA degradation leading to increase in methylated nucleotides) and the immune response as abortive infection. www.science.org/doi/10.1126/...science.orgBacteria sense virus-induced genome degradation via methylated mononucleotidesPhages often degrade the genome of their bacterial host to individual nucleotides. Here we describe Metis, a bacterial defense system that directly senses phage-mediated host genome degradation. Metis... 0140