Sign in

Alice R. Walker

@arwalker.bsky.social
1.7K followers 1.4K following 199 posts

Associate professor of computational chemistry at Wayne State University (Detroit). Computational simulations of fluorescent biomolecules. PhD@Cisneros, PD@Martinez #bifurious

PostsRepliesMedia
Reposted by Alice R. Walker
Nobel Prize @nobelprize.org · 8h
BREAKING NEWS The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
10818409
Alice R. Walker @arwalker.bsky.social · 02/10/2026
Yes, also a good way. I use Hugo which is so automated as to essentially be the same thing, mostly because I like the aesthetic
110
Alice R. Walker @arwalker.bsky.social · 02/10/2026
I think weirdly orcid is a better alternative if you really desperately don’t want to make a website but personally I like GitHub pages
230
Reposted by Alice R. Walker
Stu Cantrill @stuartcantrill.com · 01/10/2026
One for #ChemSky 👇
1266
Reposted by Alice R. Walker
Tessa Montague @tessamontague.bsky.social · 29/09/2026
My dream is to record neural activity in their brain while they camouflage so we can see how the visual world is represented in the brain & transformed into a recreation of the world on the skin. To do this, we need to generate new genetic lines: animals whose neurons fluoresce as they fire (GCaMP)
34710
Reposted by Alice R. Walker
Craig Kaplan @triggerloop.bsky.social · 25/09/2026
It is the case. The Biosketch has a certification so that happens when you generate the document. They updated the current certification to expire Sept 26. So you need new one
Action needed — Regenerate SciENcv documents before upcoming NIH and other federal submissions

The Office of Sponsored Programs (OSP) has become aware of time-sensitive issues affecting SciENcv generated documents.

SciENcv updated the digital certificate used to sign Biosketch and Current & Pending (Other) Support (CPOS) documents without notification. The old certificate expires Saturday, September 26, 2026. Documents downloaded from SciENcv before that date may fail validation in eRA Commons and generate errors that delay or block submission.

This certificate change affects applications and RPPRs to NIH, AHRQ, CDC, NIOSH, FDA, and VA submitted on or after September 26, whether they are submitted in PERIS™ MyFunding/System-to-System, ASSIST, or Grants.gov Workspace. Because SciENcv is also used to prepare Biosketch and CPOS documents for NSF, DOE, NASA, and USDA proposals, investigators with imminent submissions to those agencies are encouraged to regenerate their documents as a precaution.

What to do

Investigators should log back into SciENcv and regenerate their Biosketch and CPOS documents. When 'Download PDF' is selected, SciENcv will prompt the investigator to certify. The new PDFs should replace any older versions in in-progress applications.

October 5 R01 deadline

Any in-progress application that already includes Biosketch or CPOS documents will need those documents regenerated and replaced this coming week.
147
Alice R. Walker @arwalker.bsky.social · 17/09/2026
(Not to say everything isn’t on fire and horrible, I just also want to have hope for good students)
140
Alice R. Walker @arwalker.bsky.social · 17/09/2026
I’ve been advising students to expand their list of acceptable schools, whether that means ranking, location, etc. Everyone I know who has done so maybe didn’t get their top choice but got in somewhere.
160
Reposted by Alice R. Walker
Volker Blum @aimsduke.bsky.social · 14/09/2026
@compchemsky The next @fhi-aims.bsky.social webinar will be held on October 07 and October 08, 2026. Automated Data Generation for Machine Learning Force Fields with aims-PAX and FHI-aims Talk and Speaker: Tobias Henkes (University of Luxembourg) events.ms1p.org/event/23/
events.ms1p.org
Automated Data Generation for Machine Learning Force Fields with aims-PAX and FHI-aims
Save the date(Calendar Entry / Zoom Link) Watch on YouTube Watch on KouShare Join us for this webinar, consisting of an expert talk and interactive hands-on sessions, on automated data generation for ...
042
Alice R. Walker @arwalker.bsky.social · 14/09/2026
How to get a lot of work done: get bumped to a flight 29 hours later than your original one and be bored waiting in a French airport
010
Alice R. Walker @arwalker.bsky.social · 12/09/2026
I should also say that I am limited to students that are accepted by the university program—if a student isn’t accepted I can’t take them anyway, so it’s a naturally large filter that eliminates ~90% of people. Other departments I know it’s the other way around and the initial contact is v important
100
Alice R. Walker @arwalker.bsky.social · 12/09/2026
I do weigh it, but holistically—someone who has uniquely strong experience but a personality that wouldn’t fit in my group well or would be too rigid to learn new things wouldn’t be worth it. Hard to tell from an email tho, I often Zoom with folks in the strong category to see
000
Alice R. Walker @arwalker.bsky.social · 12/09/2026
static.klipy.com
Deathproof Stuntman Mike
Alt: Deathproof Stuntman Mike smiling and throwing cigarette
110
Alice R. Walker @arwalker.bsky.social · 11/09/2026
I count it as a plus, but usually it’s a question I’ll ask them if we get to the point of actually talking. Students that lead with it usually are interested in something I can’t give them, either topic or career wise
111
Alice R. Walker @arwalker.bsky.social · 11/09/2026
Usually if they show me that they have a genuine sounding interest in something vaguely related to what I do, it doesn’t take much. (If they write a lot about a random topic or talk in LLM circles I tend to ignore those)
110
Alice R. Walker @arwalker.bsky.social · 09/09/2026
I liked his response to hotheaded machismo as a sort of calm but strong put-down, but also I love that movie so it made many varied impressions on me haha
120
Alice R. Walker @arwalker.bsky.social · 04/09/2026
Living in the Midwest for ~30 years has apparently had no effect
Dialect map highlighting the northwest
010
Alice R. Walker @arwalker.bsky.social · 02/09/2026
I’ve seen occasional nice discussions in comments for paper posts, but few papers generate real discourse—mostly it’s just notifying your network or AI slop
010
Reposted by Alice R. Walker
Adrian Liston @labliston.bsky.social · 27/08/2026
Two post-doc positions available in our lab! It is a supportive environment and on which boosts careers! Historically, of our ~30 post-docs 27% have gone on to tenure-track positions, 27% did another post-doc, and 42% have gone on to positions in biotech or pharma.
13620
Reposted by Alice R. Walker
Tim Hathway @timdarklighter.bsky.social · 31/08/2026
Shameless plug for a cool puzzle game that uses the same critical thinking skills as structural analysis from NMR spectroscopy. (Try the ten tutorial puzzles before attempting the daily puzzle). www.multiplet.app
multiplet.app
Multiplet — Daily NMR Spectrum Puzzle
A daily puzzle game inspired by chemistry and NMR spectroscopy. Build a structure whose spectrum matches today's target.
12312
Alice R. Walker @arwalker.bsky.social · 31/08/2026
I would have put Three Men and a Tenor! Among lots of symphony orchestras and opera houses :)!
020
Alice R. Walker @arwalker.bsky.social · 31/08/2026
Simon and Garfunkel Lady Gaga Presidents of the USA Marina and the Diamonds Lily Allen Maroon 5 Flogging Molly Babymetal Kimya Dawson Final Fantasy Orchestra (Realizing that I’ve mostly gone to classical music concerts, do those count for this??)
220
Alice R. Walker @arwalker.bsky.social · 29/08/2026
Ahh one of my favorites! A tie between that one and Night Watch probably
010
Reposted by Alice R. Walker
Well-tarred Flask 🇮🇹🇺🇦🇨🇦 @chemprofcramer.bsky.social · 28/08/2026
Now that #ACSFall2026 is over, I thought I'd share my talk on the history of the Computers in Chemistry Division (presented in a HIST/PRES symposium earlier this week). Maybe some nuggets of interest for #CompChem, #ChemSky, and #SciSky... 🧪 1/14
Cover title slide reading: Past, Present, and Phenomenal Future of the Computers in Chemistry Division with my name and meeting/session details
1156
Reposted by Alice R. Walker
Erik A. Rodriguez @erin-rod.bsky.social · 28/08/2026
✨🌟The 3D-printed structure of Discosoma red fluorescent protein (DsRed)!🌟✨ The red chromophore is fluorescent due to rigidification by the white beta-barrel. We made the model using 1ZGO.pdb. #FluorescenceFriday #SciArt #FluorescentProtein
0103
Alice R. Walker @arwalker.bsky.social · 26/08/2026
One of my favorite book series of all time, I never knew Tim Curry narrated it
030
Reposted by Alice R. Walker
wendy norris @wendynorris.bsky.social · 25/08/2026
Sharing my generative AI course policy in case anybody is looking for ideas on how to frame a big ol' "nope, not for any purpose" statement. For context, I teach computational data science, AI systems, ML, and Python programming courses.
docs.google.com
Course policy on Generative AI
TL;DR: Generative AI apps (e.g., ChatGPT, Copilot, Gemini, Perplexity, Grok, etc.) are prohibited in this course. You may NOT submit any ideas, outlines, text, multimedia, images, programming code, an...
720645
Reposted by Alice R. Walker
NSF Center for Computer Assisted Synthesis (C-CAS) @nsf-ccas.bsky.social · 24/08/2026
Attending #ACSChicago? Don't miss this talk by @olexandr.bsky.social! #chemistry #ACSFall2026 #ACS #datachemistry
073
Reposted by Alice R. Walker
Nigel Goldenfeld @nigelgoldenfeld.bsky.social · 23/08/2026
Link to proposed changes and supporting information (the important bit). www.regulations.gov/docket/NSF-2... Link to make comments. www.regulations.gov/commenton/NS... Deadline: Monday 24 Aug 11.59pm Eastern. NSF: 2k comments so far. OMB: had ~ hundreds of thousands
regulations.gov
Regulations.gov
031
Reposted by Alice R. Walker
Jacquelyn Gill @jacquelyngill.bsky.social · 21/08/2026
Hey folks, this hasn’t gotten much attention, but remember those proposed OMB rule changes we all commented on recently? There’s a new attempt to sneak them just for NSF. We have three days to comment. Please don’t sleep on this!
7755637
Alice R. Walker @arwalker.bsky.social · 22/08/2026
This list is amazing and I wish I’d had it 4 years ago
000
Reposted by Alice R. Walker
Erik A. Rodriguez @erin-rod.bsky.social · 21/08/2026
Today, I would like to honor the memory of Roger Y. Tsien, who died on August 24, 2016. His legacy lives with all who use his technologies, including calcium sensors, fluorescent proteins, the acetoxymethyl (AM) ester, & many more! #FluorescenceFriday www.nature.com/articles/nme...
012939
Reposted by Alice R. Walker
I-270, Exit 1 @i270exit1.bsky.social · 14/08/2026
This plan will make peer review less transparent and more confusing to applicants and program staff. Y'all killed it on the OMB proposal, you know what to do here. Comment deadline is October 13.
14145
Alice R. Walker @arwalker.bsky.social · 12/08/2026
Current grantwriting soundtrack: Donna Lynne Champlin running the gamut of human emotion via satirical songs
010
Alice R. Walker @arwalker.bsky.social · 12/08/2026
lol the middle cat is so chonky???
000
Alice R. Walker @arwalker.bsky.social · 10/08/2026
Anecdotally I applied for tenure a little early but in the year I was hired positions were at about 1/3 of normal levels as I recall ~5 years ago. So I’d expect there to be fewer cases this year?
010
Reposted by Alice R. Walker
bioRxivpreprint @biorxivpreprint.bsky.social · 03/08/2026
Discovery of a buried charge-network GFP-fold family spanning prokaryotes and eukaryotes (Draft manuscript) www.biorxiv.org/content/10.64898/20…
022
Alice R. Walker @arwalker.bsky.social · 06/08/2026
Linkedin seems to work better for advertising papers and such, I like being a little more casual here :) the lack of AI slop is also a plus...
0120
Alice R. Walker @arwalker.bsky.social · 04/08/2026
I have fallen into the depths of summer paper land, where I only exist to review other articles and respond to reviews for my articles, and somehow still ACS has decided that I have to log in in the most roundabout way to their main website before going to the pub center #rude
010
Reposted by Alice R. Walker
Derek Lowe @dereklowe.bsky.social · 23/07/2026
Thoughts on the various Trump administration proposals to revamp US science funding - and what they all have in common:
science.org
The Assault On Science Funding Continues
3309155
Reposted by Alice R. Walker
Luke Lavis @rhodamine110.bsky.social · 17/07/2026
Excited to see this collaboration now in print. Dye chemistry meets AI-designed proteins. Three small, orthogonal tags; lifetime modulation; split versions. Request the free dyes at dyes.janelia.org www.science.org/doi/10.1126/...
science.org
De novo design of orthogonal far-red, orange, and green fluorophore-binding proteins for multiplexed imaging
Fluorescent proteins and small-molecule dyes offer complementary advantages for biological imaging: proteins are amenable to genetic tagging, whereas dyes provide superior brightness and photostabilit...
010839
Reposted by Alice R. Walker
Jay Forsythe @jaygforsythe.bsky.social · 15/07/2026
Our department is hiring! We teach and do research with undergraduates exclusively. For a PUI, we have very good facilities and instrumentation (400 MHz NMR, six MS). Great colleagues and students — about 1/3 of majors go on to Ph.D. #chemsky @chemjobber.bsky.social jobs.cofc.edu/postings/18244
jobs.cofc.edu
Assistant Professor of Chemistry and Biochemistry (organic)
Tenure-Track Assistant Professor in Organic Chemistry. The Department of Chemistry and Biochemistry at the College of Charleston invites applications for a tenure-track faculty position beginning in F...
01410
Alice R. Walker @arwalker.bsky.social · 14/07/2026
Selling handspun yarn
030
Reposted by Alice R. Walker
Dan Garisto @dangaristo.bsky.social · 10/07/2026
New: The National Science Foundation is preparing to claw back some $500 million in funds from some of its core science programs in physics, math, computer science, and engineering in order to fund a project from the White House Office of Science and Technology Policy.
nature.com
NSF plans cuts to core science programmes to fund White House initiative
A proposed clawback of already distributed research funds comes as the US agency’s budget is already squeezed and it struggling to clear a backlog of grant applications.
19426326
Reposted by Alice R. Walker
Karolina Heyduk @kheyduk.bsky.social · 14/07/2026
We're not done friends. See thread. Comment on the NSF proposal, contact your reps!
01912
Reposted by Alice R. Walker
Benjamin Pope @benjaminpope.bsky.social · 01/07/2026
cutting pure science to prioritize applications is fundamentally like asking farmers not to waste time producing grain, cheese, and tomatoes and focus on making pizzas
5346138
Reposted by Alice R. Walker
Ulm's Institute of Theoretical Physics @qubitulm.bsky.social · 11/10/2025
We are on a roll! Yet another paper from the group. Learn how biomolecular switches may profit from operating in a correlated manner, e.g. by being in contact with the same environment in a work by Rudi, Daniel and Giovanni. journals.aps.org/pra/abstract... #Quantum @quantumbiology.bsky.social
journals.aps.org
Correlated dynamics as a resource in molecular switches
Photoisomerization, a photochemical process underlying many biological mechanisms, has been modeled recently within the quantum resource theory of thermodynamics. This approach has emerged as a promis...
074
Reposted by Alice R. Walker
BejaLabTechnion @bejalab.bsky.social · 02/07/2026
Photoswitchable optoGPCRs for reversible control of Gs and arrestin signalling www.biorxiv.org/content/10.64898/2026.07.01.735182v1
0104