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Alice R. Walker

@arwalker.bsky.social

1.7K followers 1.4K following 200 posts

Associate professor of computational chemistry at Wayne State University (Detroit). Computational simulations of fluorescent biomolecules. PhD@Cisneros, PD@Martinez #bifurious

Posts Replies Media

Alice R. Walker @arwalker.bsky.social · 04/09/2026

Living in the Midwest for ~30 years has apparently had no effect

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Alice R. Walker @arwalker.bsky.social · 29/04/2026

One tenure for me, thanks ✨ From the bottom of my heart, thank you to my amazing students, colleagues, mentors, collaborators and friends. Science is a group effort and even when it’s hard I love being in it with all of you. #compchem #chemsky

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Alice R. Walker @arwalker.bsky.social · 17/03/2026

Check out our new cover art, made by the talented @markahix.bsky.social ! It highlights orbital mixing of a low barrier hydrogen bond that spans the dimer interface of YajL. Small changes tune LBHB character in homologue DJ1. With a point mutation it appears! pubs.acs.org/toc/bichaw/6...

A YajL protein dimer is shown in green and yellow protein surfaces with an interfacial aspartate/glutamate low-barrier hydrogen bond displayed with mixed-valence orbitals, calculated using quantum mechanics/molecular mechanics for each amino acid. The low-barrier hydrogen bond in the center is highlighted.

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Alice R. Walker @arwalker.bsky.social · 23/06/2025

Hmmm probably this sweater with yarn I spun myself, though it changes depending on the day 🤪 there’s a lot of counting and logic to it, like “for a curve switch 2 stitches every other row” or “add 2 to each row 8 times”, that sort of thing. So it feels a bit like assembly!

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Alice R. Walker @arwalker.bsky.social · 07/03/2025

@standupforscience.bsky.social #standupfordcience in Detroit!!

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Alice R. Walker @arwalker.bsky.social · 03/03/2025

How do fluorescent tags interact with DNA? We use computational simulations to find specific features that lead to charge-transfer on the excited state. Now out in JCIM, special edition: Editing DNA and RNA through computation (gift link): pubs.acs.org/articlesonre...

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Alice R. Walker @arwalker.bsky.social · 13/11/2024

Hi #chemsky! So excited to see a boost of liveliness again. My student Vishaka gave her 4th year talk today about designing fluorescent proteins as anion sensors, first from the group! #waynestatechem

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Alice R. Walker @arwalker.bsky.social · 19/10/2024

So pleased with my #LightBio petunia—just brought it in for the winter

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Alice R. Walker @arwalker.bsky.social · 14/02/2024

Fun trip to Düsseldorf and HHU to see Prof. Jan Meitner, enjoy Carneval and give a talk 🤩 now I am off to learn about the latest and greatest in XFEL!

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Alice R. Walker @arwalker.bsky.social · 22/11/2023

Crossposting to support my dept! #WSUchemistry is seeking applications for a full-time Pathway to Faculty Fellow to join the research team of Prof Mary Kay Pflum (@PflumLab) in the expansive field of Chemical Biology. #ChemBio #chemjobs #chempostdoc #chemsky waynetalent.csod.com/ux/ats/careers…

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Alice R. Walker @arwalker.bsky.social · 20/09/2023

Would you accept a computer dog

A small dog sleeping on slippers under a desk by a computer

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