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Antal Rot

@antalpedro.bsky.social

Reposted by Antal Rot

Johan Duchêne @johanduchene.bsky.social · 27/06/2025

#FluorescenceFriday & Erythroblast Erythroblast stimulated with CXCL12, stained for CXCR4 (green) and nuclei (blue). Captured via Correlative Light & Electron Microscopy by @jemimaburden.bsky.social Learn more: scim.ag/4kTxFZz @antalpedro.bsky.social @jffoley.bsky.social @science.org

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Neil Dufton @neildufton.bsky.social · 26/06/2025

Enjoyed a fantastic WHRI Review Day yesterday and the Dufton Group came away with not one, but two, Poster Prizes! Congrats to Dr Josh Dignam and Ms Christina Gkantsinikoudi 🏆 @qmulwhri.bsky.social

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Neil Dufton @neildufton.bsky.social · 17/06/2025

Fantastic to see a paper I played a small part of get highlighted on the Science website. Congrats to the amazing Dr Julia Gutjarh and the whole of Prof Antal Rot’s team at @qmulwhri.bsky.social @science.org

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Antal Rot @antalpedro.bsky.social · 24/06/2025

In our science.org/doi/10.1126/... we describe the hitherto overlooked erythroblast expression of CXCR4, which do not migrate in response to CXCR4 ligation by CXCL12. Instead, in these cells CXCR4 localises to the nucleus and mediates alternative cell responses in maturation and triggers enucleation

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Reposted by Antal Rot

Waggoner Lab @labwaggoner.bsky.social · 17/06/2025

CXCL12-stimulated intracellular and nuclear CXCR4 signaling mediates erythroblast enucleation to generate red blood cells www.science.org/doi/10.1126/...

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Reposted by Antal Rot

Jemima Burden @jemimaburden.bsky.social · 18/06/2025

Yesterday.. our #CLEM with Julia Gutjahr and Antal Rot was featured in the main Science webpage....☺️ Nice to see #correlativemicroscopy and #volumeEM up front and centre. www.science.org/doi/10.1126/...

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Johan Duchêne @johanduchene.bsky.social · 21/06/2025

With the right link: www.science.org/doi/10.1126/...

science.org

Intracellular and nuclear CXCR4 signaling promotes terminal erythroblast differentiation and enucleation

CXCL12-stimulated intracellular and nuclear CXCR4 signaling mediates erythroblast enucleation to generate red blood cells.

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