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The 10 × Genomics Flex Gene Expression protocol is a probe-based method that profiles fixed or frozen material, simplifying sample handling before scRNA-seq. Although probes exist only for human and m...

The question of the origin of life has haunted thinkers since the dawn of time. A recent study might have brought us closer to understanding the chemical cascade that led to our existence. And at t…

Laboratory for Molecular and Systems Biology of RNA   The Legnini Group at Human Technopole combines molecular and systems biology approaches to study gene regulation. We use synthetic biology and opt...

A 36-year-old man who was arrested by U.S. Immigration and Customs Enforcement in Minneapolis died while under the custody of federal law enforcement in Texas on Wednesday, according to the agency.

When former Harvard President Lawrence H. Summers was pursuing a romantic relationship with a woman he described as a mentee, he turned to a longtime associate for guidance: convicted sex offender Jef...

The vertebrate skeleton is formed from three embryonic lineages, each contributing to different bone types. While skeletal progenitors converge on shared functions, they retain unique molecular sig…

Jurassic Park’s warnings about scientific ambition echo today as biotech companies pursue de-extinction. However, these efforts often overlook ecological realities and distract from pressing conser…

Hidden in our DNA are “jumping genes” that usually stay silent. But sometimes they wake up, reshaping bodies in dramatic ways. A strange mutation in mice showed how one rogue element near a key lim…

Brain plasticity, the brain’s inherent ability to adapt its structure and function, is crucial for responding to environmental challenges but is usual…

The peppered moth has long been a textbook example of natural selection, its colours shifting with the soot-darkened trees of the Industrial Revolution. But the genetic secret behind its “dark” for…

The Max Planck Society is good at attracting international postdocs but struggles to retain them, survey finds.

The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...

How do you build a wing from a hand? In bats, it’s all about remixing the molecular beat. The core gene circuitry is shared with other mammals, the innovation lies in timing and context.

Here, I run though three examples of evolutionary novelty driven by single non-coding DNA changes: limb loss in snakes, gliding in sugar gliders, and coat coloration in African striped mice. These …