University of Michigan researchers uncover the role of occludin, a protein that regulates blood-brain and blood-retinal barriers, offering new insight into diabetic retinopathy.

Pediatric cancer patient at Michigan Medicine was diagnosed with ATRT and underwent chemotherapy and radiation. Four years later, he’s doing well.

Landen Silveus and Donovan Sheedy met while being treated for osteosarcoma, a type of bone cancer that affects adolescents. They supported each other through chemotherapy and surgery.

Michigan Medicine study emphasizes the need to screen for the presence of ALOX15 in cancer patients when developing prevention strategies using fish oil supplements.

Emilia Pigeon was diagnosed with neuroblastoma, a type of cancer that starts in immature nerve cells. She was treated with chemotherapy and surgery and continues to do well.

A team of researchers from Michigan Medicine tracked how glucose is used in glioblastoma tumor cells. They showed that dietary interventions can slow brain cancer growth in mice.

University of Michigan researchers have shown that a specific population of neurons in the hypothalamus help the brain maintain blood glucose levels under normal circumstances.

Diffuse midline gliomas are aggressive tumors that begin in the brain or spinal cord. It is universally fatal, and patients typically live for nine to 15 months after diagnosis. The FDA has approved O...

Abnormal changes in protein levels and patterns can result in diseases. Understanding protein organization can improve treatments and minimize disease symptoms. A team of researchers developed a new t...

Immunotherapy uses the body’s immune system to recognize and destroy cancer cells. However, many patients are resistant to this therapy, which poses a challenge to their treatment. A study led by rese...

Photoreceptor death is the cause of vision loss in many retinal diseases, and there are no effective therapies that improve their survival. In a new paper, University of Michigan researchers studied t...

Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in protein synthesis and folding. In a new study, researchers at the University of M...

Joshua Ong, M.D., resident physician at University of Michigan Kellogg Eye Center answers questions about how spaceflight affects vision and what protective measures astronauts use.

Brain and spinal cord tumors account for one in four childhood cancers. Although 75% of children survive for at least five years after being diagnosed, many patients have recurrent tumors that cannot ...

Based on former President Joe Biden's recent diagnosis, a Michigan Medicine urologists discusses routine screening procedures and treatment outcomes.

University of Michigan researchers have identified that the balance between two proteins—STAT3 and STAT5—is important for making tumors vulnerable to immune checkpoint therapy, and targeting STAT3 deg...

Researchers used mouse models and studies of colorectal cancer tissues to show that loss of SOX9 gene promotes tumor progression and the pathway it regulates can be a potential target for future treat...

Researchers investigated the combined effects of bazedoxifene and conjugated estrogens in rat models as an alternative to tamoxifen.

U-M researchers have discovered that simultaneously targeting PIKfyve and KRAS-MAPK can eliminate tumors in preclinical human and mouse models.

Physicians followed 562 patients in the U.S. and India over a three-month period to identify risk factors for eye infections that could be easily managed with early intervention.

University of Michigan researchers have created nanodiscs that can target cholesterol levels in GBM, starving the cancer cells and increasing survival rates of the treated mice.

Ethan White was diagnosed with diffuse midline glioma, a rare form of brain cancer where the survival time after diagnosis is 1-2 years. His treatment is going well and Koschmann is cautiously optimis...

Just 8 months after undergoing robotic surgery to remove his cancerous prostate, Mark Cwiek, a 70-year-old track and field athlete, successfully competed in the World Masters Athletics Championship.

Researchers at the Rogel Cancer Center, in collaboration with Arcascope, have developed and tested a personalized app that tracks a user’s circadian rhythm and makes behavioral recommendations to redu...

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Melissa Pilewskie, M.D., answers questions about how you can accurately assess your risk and what lifestyle changes can help reduce the likelihood of developing breast cancer.

Michigan Medicine experts discuss CAR T therapy, its use in other clinical trials at U-M and the new Phase I trials that started in March 2025.

Diabetic retinal disease screening remains challenging because patients often do not have any symptoms in the early stages and, therefore, misunderstand the importance of regular screenings. In a rece...

HPV screening usually entails a speculum-based exam, which is an uncomfortable experience for most patients. University of Michigan researchers are the first to demonstrate in the United States that s...

Mitochondria are essential for generating energy that fuels cells and helps them function. In a new study researchers used mice to show that dysfunctional mitochondria also trigger a response that aff...

Evan Sanders had a dirtbike accident which left him with fractures across the left side of his body. During his hospital stay, service dog Barney helped Evan with his rehabilitation goals, including a...

University of Michigan researchers found that emergency departments vary widely in how they balance the need to diagnose appendicitis with the potential harms of overtesting.

Researchers at have validated a previously developed urine test, which can potentially bypass invasive procedures for prostate cancer detection among men who are unlikely to benefit.

ATRT are rare, aggressive tumors. A lot of research has been done in identifying their cause and there are good therapies available. However, more research needs to be done. This is a Q&A article to r...