A team of researchers from the Amsterdam Leukodystrophy Center at Amsterdam UMC, led by Prof. Marjo van der Knaap, has published the first clinical evidence that the drug guanabenz may alter the cours...

A study by the Molecular Engrams team in the Department of Molecular and Cellular Neurobiology (MCN) at VU Amsterdam, published in Science Advances, has revealed distinct protein expression signatures...

Football players who head the ball during an amateur soccer match show elevated levels of blood biomarkers associated with neural damage immediately after the game, potentially indicating acute brain ...

Researchers at Amsterdam UMC, in collaboration with colleagues worldwide, have shown in a phase 3 clinical trial that a new blood-thinning medication, asundexian, reduces the risk of a new stroke by a...

In total, six projects have received a ZonMw award within the Promising Innovative Therapies program. This program supports the development of new treatments targeting the underlying mechanisms of dem...

Researchers at the Alzheimer Center Amsterdam (Amsterdam UMC) have published a study on a novel cerebrospinal fluid biomarker, AcTau174, in Nature Medicine. In this study, neuroscientists Madison Hone...

Brains are not only shaped by our experience, but also by our genes. A new study led by neuroscientists Bernardo Maciel and Martijn van den Heuvel, from the Center for Neurogenomics and Cognitive Rese...

Researchers from the Molecular Neurodegeneration and Functional Genomics laboratory of Vrije Universiteit Amsterdam and Amsterdam UMC have published a study on neuronal resilience in relation to tau pathology in the journal Science Advances. Their work describes a previously unknown intrinsic resilience mechanism that protects neurons against tau aggregation.

Vanessa Donega, Assistant Professor at the Department of Anatomy and Neuroscience at Amsterdam UMC, and Elga de Vries, Professor at the Department of Molecular Cell Biology and Immunology at Amsterdam UMC, have been awarded a grant from the Dutch Parkinson Foundation (ParkinsonFonds). The funding supports the development of a brain organoid model containing iPSC-derived microglia that mimics aging and pathological hallmarks of Parkinson’s disease.

With her expertise in neuropathology, biobanking, and high-end microscopy analysis of human brain tissue, Wilma Van de Berg aims to improve early diagnosis and develop disease-modifying therapies for Parkinson’s disease. In her inaugural lecture on December 18, 2025, Professor Wilma Van de Berg will bring together different perspectives on disease progression as the newly appointed Professor Cellular Neurodegeneration, Parkinson’s disease at the Vrije Universiteit Amsterdam.

Associate Professor of Integrative Neurophysiology Natalia Goriounova (VU Amsterdam, Center for Neurogenomics and Cognitive Research) has been awarded a prestigious ERC Consolidator grant for her HumanCircuits project. Over the next five years she will study neurons in living tissue from the human brain.

Psychiatrist and Professor of Stress and Resilience Christiaan Vinkers (Amsterdam UMC, GGZ inGeest) has been awarded a prestigious ERC Consolidator grant for his project RHYTHM. Over the next five years he will investigate how the daily rhythm of the stress hormone cortisol helps explain why some people remain mentally healthy under pressure, while others develop depression or anxiety. And how this knowledge can be used to improve treatment.

A new Dutch consortium, led by the University of Amsterdam, has joined forces to accelerate progress in the field of neurotechnology even further. The EBRAINS-Neurotech consortium – supported by an €18.3 million grant from the Dutch Research Council – brings together nine Dutch institutions to build cutting-edge tools for brain research and treatment.

Researchers at Amsterdam UMC have identified antibodies that target the body's own immune system are associated with a higher risk of developing bacterial meningitis. The study, recently published in eBioMedicine, provides important new insight into why some individuals develop severe disease following infection with the pneumococcal bacterium, the most common cause of bacterial meningitis worldwide.

Altered lipid metabolism in the brain is a key feature of many neurodegenerative diseases, yet comparing lipid data across studies has remained a challenge. To address this, Femke Feringa, Sascha Koppes-den Hertog, and Rik van der Kant, together with team of Martin Giera at LUmc, have developed the Neurolipid Atlas.

Working together on mental health: academic ecosystem Psychiatry Amsterdam  ‘Psychiatry Amsterdam’, as an ecosystem, is led* by the department of Psychiatry, Amsterdam UMC. Together with our partners ...

Amsterdam UMC is launching unique consultation hours for patients with ‘smoldering MS’. This form of Multiple Sclerosis involves gradual disease progression even without active inflammation in the brain. During the special consultation hour, these patients will receive tailored treatment advice. The initiative is partly based on research into age and MS by neurologist Eva Strijbis and radiologist Frederik Barkhof of Amsterdam UMC, recently published in Nature Reviews Neurology.

Lithium en de ziekte van Alzheimer worden al tientallen jaren met elkaar in verband gebracht. Nieuw onderzoek van de Harvard University laat zien dat een tekort aan lithium Alzheimer kan veroorzaken e...

YouTube video by Amsterdam UMC