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Alok Khorana, MD, FACP, FASCO

@alokkhorana.bsky.social
1.1K followers 379 following 11 posts

Hardis Endowed Chair in Oncology Research, Prof of Medicine, Director GI Cancer Program, Cleveland Clinic. Physician/Scientist/Writer. Opinions mine. #MedSky #Oncosky

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Alok Khorana, MD, FACP, FASCO @alokkhorana.bsky.social · 08/07/2025
Our latest paper with @ClevelandClinic investigators and RoswellPark colleagues Iyer, Vadehra, Fountzilas finds distinct microbiotic profiles of early onset pancreatic cancer and an association with survival @myesmo.bsky.social www.sciencedirect.com/science/arti...
sciencedirect.com
Tumor microbiome differences in early-onset versus average-onset pancreatic adenocarcinoma
Compelling evidence supports the biomarker potential of microbiome in pancreatic adenocarcinoma. Given the knowledge gap on the characteristics and si…
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Reposted by Alok Khorana, MD, FACP, FASCO
Saskia Middeldorp @middeldorps.bsky.social · 22/06/2025
This is what we were waiting for. A direct comparison between apixaban and rivaroxaban for the treatment of acute VTE. Apixaban reduces bleeding risk in the first 3 months by >50%! Practice changing investigator-initiated RCT. #ISTH2025
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Reposted by Alok Khorana, MD, FACP, FASCO
Marc Carrier, MD @marccarriermd.bsky.social · 24/06/2025
🩸 WaVE Study Alert! In patients with acute CAT & weight >90kg, weight-based dalteparin (200 IU/kg) appears safe & effective. 🔹 Anti-Xa levels aligned with non-obese patients 🔹 Higher levels seen in those with bleeding Important data to guide dosing CAT & obesity. 📍Presented by Dr. Wang at #ISTH2025
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Reposted by Alok Khorana, MD, FACP, FASCO
Marc Carrier, MD @marccarriermd.bsky.social · 24/06/2025
🚨 SPECTACULAR RCT at #ISTH2025! Although non-inferiority to CTPA wasn’t shown, a negative SPECT V/Q scan led to low 3-month VTE risk— ✅ Supporting the safety of ruling out PE with a SPECT-based algorithm 📸 PE diagnosis rates matched other validated strategies SPECTacular findings indeed! 🫁💥
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Reposted by Alok Khorana, MD, FACP, FASCO
Marc Carrier, MD @marccarriermd.bsky.social · 23/06/2025
Meta-analysis on GLP-1RA (vs. placebo) and VTE: 🔹 PE rates significantly lower 📉 🔹 VTE rates lower but not statistically significant 🔹 No difference in DVT 🔹 Study design matters: RCTs vs. observational data Accepted for publication in JTH! #ISTH2025 #VTE #GLP1RA #Thrombosis @jthjournal.bsky.social
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Reposted by Alok Khorana, MD, FACP, FASCO
Marc Carrier, MD @marccarriermd.bsky.social · 24/06/2025
Implementation matters! A guideline-driven VTE prevention program (Vermont Model) led to ~60% of high-risk cancer patients receiving prophylactic anticoagulation—resulting in a 60% reduction in VTE and 56% reduction in death. #ISTH2025 #VTEprevention 🩸 @marycushmanmd.bsky.social
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Alok Khorana, MD, FACP, FASCO @alokkhorana.bsky.social · 22/05/2025
Time to Treatment Initiation for the 30 Most Prevalent Cancer Types: Trends and Predictors of Change | JCO Oncology Practice ascopubs.org/doi/10.1200/...
ascopubs.org
Time to Treatment Initiation for the 30 Most Prevalent Cancer Types: Trends and Predictors of Change | JCO Oncology Practice
PURPOSEAs the complexity and need for cancer care services continue to grow, time to treatment initiation (TTI) has been increasing across cancer types. Presently there are no comprehensive analyses i...
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Reposted by Alok Khorana, MD, FACP, FASCO
Mike Pishvaian @mpishvaian.bsky.social · 11/01/2025
#GI25 @ascocancer.bsky.social Two trials on the tissue factor⛔️, pamrevlumab (PAM) in #PancreaticCancer, both by Dr. Piccozzi: 1⃣LAPIS, a R-Ph3 trial of chemo +/- PAM for LAPC, Oral Abstract #675 2⃣The Precision Promise trial @pancan.bsky.social of PAM+gem/nab-pac for mPDAC, Oral Abstract # 673
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Reposted by Alok Khorana, MD, FACP, FASCO
Heloisa Soares @heloisasoares.bsky.social · 23/01/2025
Thrilled to listen to the incredible #GI25 keynote speaker @pamelakunzmd.bsky.social inspiring us all with her leadership in inclusive science in GI oncology! @ascopost.bsky.social @halletjulie.bsky.social @drcnclarke.bsky.social @rachnatshroff.bsky.social @nanets.bsky.social
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Reposted by Alok Khorana, MD, FACP, FASCO
Morgan S. Levy, MD, MPH (she/her) @morganslevy.bsky.social · 24/01/2025
HPV vaccines prevent cancer and save lives. As an oncologist in training, I regularly see the burden and suffering that HPV related cancers cause for my patients. It will involve continuing to build trust, but addressing vaccine hesitancy is vital. #radonc #gyncsm academic.oup.com/jid/advance-...
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Reposted by Alok Khorana, MD, FACP, FASCO
Jame Abraham, MD, FACP @jameabraham.bsky.social · 13/12/2024
my.clevelandclinic.org/podcasts/can... @clevelandclinic.bsky.social @alokkhorana.bsky.social
my.clevelandclinic.org
Integrated Program for Young People with Cancer
Chair of the Department of Colorectal Surgery, Director of the Weiss Center for Hereditary GI Neoplasia and Center for Young Onset Colorectal Cancer, David Liska, MD, joins the Cancer Advances Podcast...
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Alok Khorana, MD, FACP, FASCO @alokkhorana.bsky.social · 19/11/2024
Important for patients unable to access Creon for financial reasons #pancreaticcancer
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Reposted by Alok Khorana, MD, FACP, FASCO
Journal of Thrombosis and Haemostasis @jthjournal.bsky.social · 19/11/2024
Suggested read for you today 👀 #Medsky #Cancer #HemeSky #OncSky
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Reposted by Alok Khorana, MD, FACP, FASCO
Emil Lou, MD, PhD, FACP, FASCO @cancerassassin1.bsky.social · 16/11/2024
James Van Der Beek, Jenna Fischer and the rise of young people getting cancer in @usatoday.com www.usatoday.com/story/life/h...
usatoday.com
James Van Der Beek, Jenna Fischer and the rise of young people getting cancer
Why are young people getting cancer at higher rates? No one knows, but here's how to stay proactive and vigilant.
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Alok Khorana, MD, FACP, FASCO @alokkhorana.bsky.social · 14/11/2024
Nice new validation of Ang Li's risk score in JTH, first in non-US population (albeit using diagnostic codes rather than chart review) www.jthjournal.org/article/S153...
jthjournal.org
DEFINE_ME
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Reposted by Alok Khorana, MD, FACP, FASCO
Med Peds Hospitalist @medpedshosp.medsky.social · 12/11/2024
Tips and tricks for Bluesky search bsky.social/about/blog/0...
bsky.social
Tips and Tricks for Bluesky Search - Bluesky
Let’s dive into all the tips and tricks for advanced Bluesky search!
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Reposted by Alok Khorana, MD, FACP, FASCO
Madhu Pai, MD, PhD @madhupai.bsky.social · 12/11/2024
Science should save all, not just some www.science.org/doi/10.1126/...
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Reposted by Alok Khorana, MD, FACP, FASCO
DSP💙#🟦✡️ @drawstickpeople.bsky.social · 11/11/2024
I'm making a Starter Pack of Oncology accounts that will include health care (clinical & research), advocates, & patients. If you're unfamiliar, Starter Packs are a 📃 of accts that can be easily followed Please reply to this post with any recommendations, including yourself ~dsp #oncosky #medsky
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Alok Khorana, MD, FACP, FASCO @alokkhorana.bsky.social · 11/11/2024
Found this very useful as a newbie
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Reposted by Alok Khorana, MD, FACP, FASCO
Eric Topol @erictopol.bsky.social · 10/11/2024
High-resolution of cancer. Unprecedented. A brief review of what we've just learned from 17 new papers in the latest edition of Ground Truths. It's free, open-access. erictopol.substack.com/p/cancer-sci...
erictopol.substack.com
Cancer Science in On a Tear
New insights on evolution, resistance, and therapies
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Reposted by Alok Khorana, MD, FACP, FASCO
Richard Ferro, MD MSc @richferro.com · 17/10/2024
Welcome new Bluesky users! There's lots of advice being posted for new users at the moment. This thread is tailored for the STEM, academic, and medical people, and I hope this helps you find your community! For starters, here's a starter pack full of medical accounts worth checking out!
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