The hyphae-to-yeast morphological transition promotes dissemination of the pathogen Candida albicans, but the mechanisms underlying this process are poorly defined. By identifying a bacterial metaboli...

A new jab extended the length of time patients were cancer free, but it is unclear for how long.

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In this Review, Wood and colleagues discuss how anthropogenic pressures are degrading soil and sediment microbiomes, propose restoration strategies and emphasize the importance of integrating microbio...

Bacterial genome evolution is shaped by epistasis, which can constrain or promote specific evolutionary paths. The authors review how integrating the effects of epistatic interactions into population-...

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Inactivation of chromosomal genes through plasmid-encoded IS elements is an extended mechanism of antimicrobial resistance evolution in bacteria.

Evo 2 is an artificial intelligence-based biological foundation model trained on 9 trillion DNA base pairs spanning all domains of life that predicts functional properties from genomic sequences and p...

In the ocean, viruses are known to mediate the carbon cycle, keeping dissolved organic carbon (DOC) in the microbial loop and preventing its movement into secondary consumers (1). However, few direct ...

Reconstructing microbial genomes from 820 reef-building corals collected at 99 reefs across 32 islands throughout the Pacific Ocean highlights the importance of conserving coral reefs as vital reservo...

Barcoding microbial ribosomal RNA creates a record of gene transfer events without requiring translation. Kalvapalle et al. designed catalytic RNAs to...

Accurately predicting coding genes from metagenomic samples containing a high proportion of eukaryotic content remains a significant challenge. Novel and reliable methods for the simultaneous predicti...

Abstract. Microorganisms have profoundly shaped Earth’s biological and geological history, from the origins of oxygenic photosynthesis to present-day globa

Covering: 2005 to July 2025Methicillin-resistant Staphylococcus aureus (MRSA), emerging as one of the most common multidrug-resistant (MDR) bacterial strains, has posed a serious threat to global heal...

Plasmids are extrachromosomal DNA molecules that spread by horizontal transfer and shape bacterial evolution. Plasmids are typically present at mul...

A library of 400 phage protein-coding genes is used to find a trove of antiphage systems, revealing systems that target tail fibre and major capsid proteins.

Zhou et al. report the one-pot production of colored bacterial cellulose (BC) as a sustainable alternative to petroleum-based fabrics. Metabolic engineering enhanced colorant yields, while co-culture ...

There are increasing concerns that continued economic growth in high-income countries might not be environmentally sustainable, socially beneficial, o…

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Integrons are bacterial genetic elements that capture, stockpile, and modulate the expression of genes encoded in integron cassettes. Mobile integrons (MIs) are borne on plasmids, acting as a vehicle ...

Covering: 2014 up to February 2025Since the Nagoya Protocol came into force in 2014, scientists working with genetic resources have integrated compliance with Access and Benefit-Sharing (ABS) legislat...

Bacterial secondary metabolites are crucial bioactive compounds with significant therapeutic potential, playing key roles in ecological processes and the discovery of novel antimicrobial agents and na...

In decades of deep-sea exploration, humans have observed only 0.001% of the deep seafloor, leaving 66% of planet Earth unseen.