Scientists share help and advice on how they got their research discussions flowing.

Knudsen and colleagues use repli-ATAC-seq to compare replicated and unreplicated chromatin in two models of cell identity change. They find that lineage-specific elements are accessible earlier in rep...

DNA secondary structures, such as hairpins, cruciforms, triplexes, G-quadruplexes and iMotifs, are common, dynamic features that replication forks rou…

From today, all new submissions to Nature that are published will be accompanied by referees’ reports and author responses — to illuminate the process of producing rigorous science.

Losing parental histones during DNA replication fork passage challenges differentiation competence and cell viability.

Scientists and engineers often spend days choosing a problem and years solving it. This imbalance limits impact. Here, we offer a framework for problem choice: prompts for ideation, guidelines for eva...

Aditya Sethi, one of the co-authors of a paper just published in Nature Comms, explains how it offers new insights into how different cell types are generated during animal development, which in futur...