Respiratory metagenomic sequencing is increasingly used for rapid, pan-microbial diagnosis in clinical practice, but there is a need to evaluate different wet lab protocols for performance and feasibi...

Respiratory metagenomic sequencing is increasingly used for rapid, pan-microbial diagnosis in clinical practice, but there is a need to evaluate different wet lab protocols for performance and feasibi...

Snell et al. develop sequencing methodology to identify full-length spike haplotypes and show that persistent SARS-CoV-2 infections drive divergent haplotype emergence, accelerating viral evolution an...

Syphilis has re-emerged as a global public health concern. Although serology is well established, the role of PCR remains unclear. We evaluated the di…

As a new branch of H3N2 influenza gains ground, we explore what it means for this season’s flu vaccine.

Metagenomics is being adopted worldwide as a laboratory developed test. We have previously reported a unified metagenomic method for the direct detection of microorganisms from respiratory samples, de...

A new diagnostic test that can detect a broad range of microorganisms in a single sample and give same-day results has been shown to improve the diagnosis and treatment of patients with…

Respiratory metagenomics for ICU patients showed good performance and turnaround time, and diverse clinical and public health benefits. This ability to inform both personalised patient therapy and inf...

Paracetamol medicines can be used in pregnancy, in accordance with official recommendations

This Viewpoint describes the World Health Assembly’s newly adopted Pandemic Agreement, which lays a framework for action including preventing zoonotic spillovers, health system preparedness, and equit...

Current methods are insufficient alone for outbreak detection in hospitals. Real-time genomic surveillance offers the potential to detect otherwise unidentified outbreaks.

Hybridization capture approaches can significantly increase the sensitivity of metagenomics. However, their implementation with Oxford Nanopore Technologies (ONT) sequencing has been limited due to th...

The 25 most downloaded papers published in Communications Medicine in 2024

The 25 most downloaded papers published in Communications Medicine in 2024

Alcolea-Medina et al. develop a rapid, unified metagenomics method for the detection of bacteria, fungi, and viruses from clinical respiratory samples. This method reduces human DNA content, allowing ...