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Antonio Guerrero MD PhD

@guerreroespejo.bsky.social
598 followers 329 following 600 posts

Infectious diseases physician and clinical microbiologist retired| Valencia (Spain)

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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 05/10/2026
Could the next pertussis vaccine be intranasal? A phase 2b trial in children aged 6–17 found BPZE1, a live attenuated intranasal vaccine, immunogenic and well tolerated. Clinical efficacy and impact on transmission still need to be shown. 👇 doi: 10.1016/S1473-3099(26)00470-6. #Pertussis #Vaccines
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 05/10/2026
#Measles 2026, four continents: 👉Americas 52,480 confirmed cases (PAHO, Sep 7); - US, within the Americas, 3,887 cases (Oct 1) 👉Bangladesh 20,124 confirmed and 172,720 suspected; 👉Africa 143,222 suspected and 1,392 deaths (Africa CDC);(1/2) #IDSky #epidemiology
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 04/10/2026
West Nile virus in Europe: 1,765 locally acquired human cases in 16 countries by 30 September. Italy 721, Greece 420, Spain 131 and France 128. ECDC identified 202 affected areas, including 16 newly reported this week #WestNileVirus ECDC, Week 40 WNV surveillance, datos hasta 30 septiembre 2026.
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 04/10/2026
Europe, carbapenem-resistant Klebsiella pneumoniae: ➡️NDM (New Delhi metallo-β-lactamase) carriers rose from 20% (2019) to 50% (2025) of isolates; ➡️KPC (Klebsiella pneumoniae carbapenemase) fell from 50% to 25%. Preliminary ECDC data, 21 countries. (1/2) #microbiology #IDSky
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 03/10/2026
🌍 Why do outbreaks emerge? Nature analysed 58,319 events involving 32 diseases across 169 countries. Drivers were disease-specific. Strikingly, outbreak reporting fell by a median 32% for each additional hour of travel to a health facility. #Epidemiology #IDSky
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 01/10/2026
#Ebola #DRC: - cases fell 26% in Ituri and 15% in Haut-Uele over 21 days, but rose 73% in North Kivu (WHO). - 1 in 3 new cases is identified only after the patient has died, outside treatment centers. (1/2) #IDSky #medicine
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 30/09/2026
The super El Niño is cooking coral reefs — can lullabies and probiotics save them? www.nature.com/articles/d41...
nature.com
The super El Niño is cooking coral reefs — can lullabies and probiotics save them?
Researchers are trying everything they can to help coral reefs to survive severe heat stress from climate change, including playing sounds underwater.
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 30/09/2026
#Cholera 2025: WHO recorded 451,499 cases and 7,870 deaths worldwide —the highest annual death toll since 1999— even as case numbers fell. Seven countries account for 90% of the global burden. Source #WHO: www.who.int/news-room/fa...
who.int
Cholera
Cholera is an extremely virulent disease. It affects both children and adults and can kill within hours if left untreated. Severe cases need rapid treatment with intravenous fluids and antibiotics.
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 30/09/2026
Clinical case (1/3) 37-year-old man with spina bifida. Fifteen years earlier: cystectomy + continent cutaneous urinary diversion for neurogenic bladder. Now: abdominal knocking while walking + palpable right-sided mass X-ray: what do these calcifications represent? #MedEd #Medicine #clinicalcase
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 29/09/2026
🧠 Clinical case A 25-year-old man with HIV on ART (CD4: 218/mm³) presents with headache and diplopia. Examination shows an isolated right VI nerve palsy. He also has low-back pain and constipation. 👁️ What is your differential diagnosis? #MedEd #IDSky #neurology #clinicalcase
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 28/09/2026
Locally acquired #dengue in #Italy: from 3 cases (Sep 2) to 47 (Sep 23), confirmed by ISS. #France stays at 5, no active clusters. Zero dengue deaths in Italy this season. Source (ECDC): www.ecdc.europa.eu/en/publicati...
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 28/09/2026
#Denmark: 6 severe cases of #iatrogenic #botulism after botulinum #toxin (hyperhidrosis/cosmetic). An unapproved product is suspected, not confirmed. ECDC: low risk. Source: www.ecdc.europa.eu/en/publicati...
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 27/09/2026
#Ebola DR #Congo: now the largest outbreak in the country's´history (WHO). It has reached zones bordering CAR and South #Sudan (63 zones, 7,890 cases), but no confirmed cases in either country yet. Source: www.who.int/emergencies/...
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 19/09/2026
#Ebola in #DRC: ➡️ only 64% of people in Ituri believe the disease is real (ActionAid). 1 in 3 does not —worse than in 2018-19 (25%). Source: www.actionaid.org.uk/latest-news/...
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 18/09/2026
WHO published in June the first unified clinical guideline for all #filoviruses ( #Bundibugyo, #Ebola, #Sudan, #Taï Forest, #Marburg): ➡️ 16 evidence-based recommendations on supportive care, with no approved vaccine or antiviral for most. Source: www.who.int/publications...
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 17/09/2026
#ESBL colonization pressure In 24 European #neonatal units, every 10% increase in ESBL (Extended-Spectrum β-Lactamase) colonization pressure was associated with a 73–89% higher odds of acquisition. DOI: 10.1001/jamanetworkopen.2026.32644. #AMR
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 16/09/2026
#Cefepime and mortality: Is cefepime completely safe? A Bayesian meta-analysis of 110 RCTs (22,608 patients) found a 94.4% posterior probability of higher mortality vs other β-lactams. An important signal—but not a reason to abandon cefepime. DOI: 10.1001/jamanetworkopen.2026.33017#IDTwitter
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 15/09/2026
#Mpox 2026: ➡️ #Madagascar is facing the largest outbreak on record (3,436 cases/22 deaths, 65% of districts, not under control). ➡️ Globally: 1,370 cases in 32 countries in July, risk "moderate". New vaccine access mechanism launched in August. Source (WHO): www.who.int/news-room/fa...
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 14/09/2026
West Nile #virus: ➡️ worst #US season in 20+ years (222 cases/32 states as of Aug 18, tracking 2003s curve, 70% neuroinvasive). ➡️ #Europe: 1,086 autochthonous cases as of Sept 3, France jumped from 18 to 56 in two weeks. Source (CDC): www.cdc.gov/west-nile-vi... #MedSky #IDSky #microbiology
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Reposted by Antonio Guerrero MD PhD
TRAstonDrs @castltrastondrs.medsky.network · 13/09/2026
#Medsky🧪 #IDsky #episky #microsky #publichealth Primary infection of #varicellazostervirus causes #chickenpox & can reactivate later in life, leading to shingles & complications. A Primer in @nature.com covers its epidemiology, diagnosis, and management. www.nature.com/articles/s41...
nature.com
Varicella zoster virus infection
Nature Reviews Disease Primers - Primary infection of varicella zoster virus causes varicella (chickenpox). Virus reactivation later in life can cause herpes zoster (shingles) and other...
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 13/09/2026
#Infant #botulism, two formula brands: ▶️ genomic sequencing linked the ByHeart (28 cases) and Nara Organics (4) outbreaks to the same organic milk powder supply chain in #US. Both are now closed. Source (CDC): www.cdc.gov/botulism/out... #IDSky #Medicine
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 11/09/2026
🌍 #Rabies Update 2024: ▶️High risk remains in Asia & Africa. ▶️The standard for travelers: a simplified 2-dose PrEP schedule (Days 0, 7); excellent protection & easier travel prep. Being pre-vaccinated saves lives simplifies post-exposure care. who.int/health-topic... #TravelMedicine #PublicHealth
who.int
Rabies
Rabies is a viral zoonotic disease that causes progressive and fatal inflammation of the brain and spinal cord.
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 10/09/2026
#Measles 2026: ➡️ started with a global decline, but specific hotspots exploded. ➡️ Bangladesh: 18,578 cases/943 deaths. ➡️ Americas: 47,500 cases, "very high" risk. ➡️ Europe: 6 countries lost elimination status. Source: www.who.int/news-room/fa... #IDSky #microbiology
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 09/09/2026
#Lyme disease worldwide: ➡️the US reported 89,000 cases in 2023, but the CDC estimates true incidence at ~476,000/year (5x underreporting). ➡️Europe: >85,000 estimated cases/year, steadily rising. Source (CDC): www.cdc.gov/lyme/data-re... #IDSky #medicine #microbiology
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 08/09/2026
#H5N1 #bird #flu: ➡️ 1,022 human cases since 1997, ~48-50% fatality. ➡️ No confirmed human-to-human transmission. ➡️ The real concern is spread to mammals (cattle, seals). ➡️ Population risk: low (WHO/CDC). Source: www.cdc.gov/cfa-qualitat... #IDSky #medicine #microbiology
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Reposted by Antonio Guerrero MD PhD
cosmด้้้้pático 🔻🦋 @cosmopatico.eurosky.social · 07/09/2026
Esta foto muestra dos mapamundis superpuestos. En azul, el que suele utilizarse y que emplea la llamada ‘escala de Mercator’ y exagera el tamaño de Estados Unidos, Canadá, Escandinavia y Rusia; en rojo, la versión corregida y más fiel a la realidad. vía @eldiario.es
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Reposted by Antonio Guerrero MD PhD
Instituto de Salud Carlos III (ISCIII) @isciiisalud.bsky.social · 07/09/2026
🆕 #InvestigaciónISCIII IA para detectar en tiempo real y a bajo coste desde un teléfono móvil la enfermedad de Chagas. 🤝 En colaboración con @ciberisciii.bsky.social @upm.es, Spotlab, @mundosano.bsky.social y la Universidad de San Simón de Bolivia. 📰 #NoticiasISCIII ⬇️ www.isciii.es/w/ia_para_de...
isciii.es
IA_para_detectar_desde_el_movil_enfermedad_de_Chagas
Un estudio con participación del ISCIII ha utilizado inteligencia artificial para detectar en tiempo real y a bajo coste desde un teléfono móvil el parásito que causa la enfermedad de Chagas.
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 07/09/2026
Autochthonous #dengue in #Europe: ▶️ #Italy joins #France this season (3 cases, 2 new clusters). ▶️ Combined total: 8 cases, 4 of 6 clusters still active. ▶️ Aedes albopictus is now established across southern Europe. Source (ECDC): www.ecdc.europa.eu/en/dengue #IDSky #microbiology
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 06/09/2026
A newly identified #tick-borne #orthonairovirus may explain part of the febrile illness currently classified as SFTS but negative for Dabie bandavirus. Among 3,163 febrile patients in #China, ALTNV was detected in 10.4%. Coinfection with DBV: more severe disease. 👇 DOI: 10.1056/NEJMc2602496
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 05/09/2026
#Measles 2026, four continents: ▶️Europe loses elimination status in 6 countries. ▶️Americas: 47,500 cases. ▶️Bangladesh: 18,578 confirmed, 943 deaths. ▶️DRC: 10,000+ in South Kivu. Same pattern: localized low coverage. Source: www.who.int/europe/news #vaccine #IDSky
who.int
News
News from the World Health Organization
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 04/09/2026
#Ebola #DRC: 6,186 cases, 3,007 deaths — past 3,000. MSF calls in The Lancet for children under 20kg to join trials of obeldesivir, the oral #antiviral tested as post-exposure prophylaxis. Source: www.ecdc.europa.eu/en/ebola-out...
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 02/09/2026
#Mosquito #control may prevent a bacterial disease. In a randomized field trial in Melbourne, autodissemination stations reduced Aedes notoscriptus egg counts by ~70%. An exploratory analysis also suggested lower #Buruli ulcer risk. Nature Microbiology DOI: 10.1038/s41564-026-02439-8
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 01/09/2026
Could an oral #antiviral replace foscarnet for refractory #HSV in #immunocompromised patients? In a small randomized phase 2 trial, lesion healing was 93% with pritelivir vs 57% with foscarnet (not statistically significant, but efficacy & safety support phase 3 evaluation) DOI: 10.1093/ofid/ofag539
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 01/09/2026
#Chandipura #virus in #India: the #outbreak worsens. Gujarat now has 35 confirmed cases and 22 child deaths (up from 12/3 in July). The vector remains unconfirmed. No vaccine or antiviral exists. iihmr.edu.in/jaipur/chand...
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Reposted by Antonio Guerrero MD PhD
ESCMID @escmid.bsky.social · 19/08/2026
🚨 New Epi Alert: DRC reports its largest-ever Ebola outbreak. CCHF expands into Albania, a previously non-endemic area & West Nile virus spreads across Europe. Plus: Zika in travellers from Bali, Japanese encephalitis in India & cyclosporiasis in the US. ow.ly/9HJm50Y3Qs0 #IDSky #clinmicro
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 31/08/2026
Could #Bourbon #virus be circulating more widely than recognized? Neutralizing antibodies increased over time in #US plasma-derived lots from 2006–2024, while European lots were largely non-reactive. Indirect but intriguing evidence of underrecognized circulation. DOI: 10.1093/infdis/jiag442
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 31/08/2026
#Chikungunya in #France: sustained local #transmission. 15 cases (Aug 17) → 25 (Aug 24) → 33 (Aug 26), active clusters doubling in a week. #Aedes albopictus is now established across southern Europe. Source (ECDC): www.ecdc.europa.eu/en/chikungun...
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 29/08/2026
Improvement in the #incidence of #dengue in the #Americas, 2026: 👉1,432,399 cases (week 28), down 61% vs 2025 and 67% vs the 5-year average. 👉Contrast with 2024, the worst year on record (12.6M cases, 7,700 deaths). 👇 Source (PAHO): www.paho.org/en/topics/de...
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 29/08/2026
In 41 hospitals across 19 #Asian countries/regions, 👉73.7% of 9,642 severe healthcare-associated #infections involved antimicrobial-resistant bacteria. 👉28-day mortality was 37.7%, 👉reaching 51.3% with carbapenem-resistant Acinetobacter. 👇 Lancet Infect Dis. DOI: 10.1016/S1473-3099(26)00357-9
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 28/08/2026
A 4-YO boy: a 5-day history of mild fever and malaise and a 3-day history of a vesicular rash involving his hands (A), feet (B), tongue (C), and buttocks. ½ DOI: 10.1056/NEJMicm0910628 #Pediatrics #children #MedEd #medicine #emergency
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 28/08/2026
Same virus (Bundibugyo), two outcomes: ➡️ Uganda closed its outbreak (20 cases, 2 deaths). ➡️ DRC keeps expanding (5,713/2,744). Key: Ituri is an active conflict zone, hampering surveillance and response. Source: www.ecdc.europa.eu/en/ebola-out... #Ebola #MedSky
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 27/08/2026
#Lassa #fever in #Nigeria: ➡️ 1,000 cases and 237 deaths in 2026 (23.7% CFR, up from 18.8% at the same point in 2025). ➡️53 healthcare workers infected. ➡️Five states account for 86% of cases. Source (NCDC): ncdc.gov.ng/diseases/sit...
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 27/08/2026
#Zoonoses in #Europe: ➡️Some like Lyme, listeriosis, brucellosis, echinococcosis and toxoplasmosis DO have harmonized EU surveillance, mostly rising. ➡️Others like babesiosis, relapsing fever, murine typhus and fascioliasis do NOT. Source (ECDC): www.ecdc.europa.eu/en/publicati...
ecdc.europa.eu
Publications and data
ECDC collects data on a number of topics in the area of infectious diseases. There are made accesible in various formats, such as interactive databases and dashboards.
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 26/08/2026
One challenge in chronic #Chagas disease is knowing early whether treatment is working. A multiplex #serological assay detected antibody⬇️within 6 months & distinguished active treatment from placebo, unlike conventional ELISA. A biomarker—but not yet a marker of cure. 👇 DOI: 10.1093/infdis/jiag427
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 25/08/2026
IPV induces more than systemic immunity: it also generates nasal poliovirus-specific antibodies. In 500 infants challenged with nOPV2, pharyngeal shedding was minimal after both IPV and bOPV. DOI: 10.1093/infdis/jiag423 #vaccine #polio
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 25/08/2026
A 26-YO ♂️, smoker, his daughter had chickenpox: rash with vesicles, pustules, & crusty lesions (A), cough, fever, & mild dyspnea CXR: small nodules (B) CT: ill-defined nodules, coalescence & surrounding halos of ground-glass attenuation (C) ½ DOI: 10.1056/NEJMicm0902199 #MedEd #radiology #medicine
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 25/08/2026
WHO maintains the #Ebola #PHEIC (Public Health Emergency of International Concern) in #DRC and raises the national risk to "very high". New measures: river surveillance toward Kinshasa, capacity limits, one passenger per motorbike. No travel restrictions Source: www.ecdc.europa.eu/en/ebola-out...
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 24/08/2026
Candidozyma auris can spread silently through colonized patients During a hospital outbreak, universal PCR screening reduced detection time to ~20 hours &, combined with infection-control measures, halted transmission Rapid detection may be critical for outbreak control. 👇 DOI: 10.1093/cid/ciag493
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 24/08/2026
#Mpox 2026: global trend declining since May 2025. In the EU/EEA (Jul25-Jun26): ➡️829 clade I and 921 clade II cases across 18 countries each. ➡️90-91% among MSM. ➡️Only about 1 in 5 fully vaccinated. Source (ECDC): mpox-monthly.ecdc.europa.eu #vaccine #IDSky #microbiology
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Antonio Guerrero MD PhD @guerreroespejo.bsky.social · 23/08/2026
In a Chinese cohort of 889 #cancer patients receiving immune checkpoint inhibitors, 44 developed active #TB (2,693/100,000 person-years). Causality cannot be established, but it supports careful TB screening strategies in high-burden settings before #immunotherapy. 👇 DOI: 10.1093/ofid/ofag517
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