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Adam Cribbs

@adamcribbs.bsky.social
337 followers 809 following 14 posts

#MRC CDA fellow, University of Oxford, long-read sequencing| single-cell technology development| multiple myeloma| bone cancer

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Adam Cribbs @adamcribbs.bsky.social · 06/05/2025
📢 New preprint alert! We present UMIche, a modular, open-source platform to improve UMI-based molecular quantification in bulk and scRNA-seq data. → Integrated pipelines → Monomer & homotrimer UMIs → Deep learning-based simulation 🔗 doi.org/10.21203/rs....
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Reposted by Adam Cribbs
Carla Cohen @drcarlacohen.bsky.social · 16/04/2025
Ever torn a tendon? Our study led by @joletmimpen.bsky.social discovered changes in fibroblast and immune cell populations that occur in quadriceps tendon tears. Read more: doi.org/10.1113/JP28... @sarahsnelling.bsky.social @adamcribbs.bsky.social
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Reposted by Adam Cribbs
bioRxiv Genomics @biorxiv-genomic.bsky.social · 12/03/2025
FlowAgent: A Modular Agent-Based System for Automated Workflow Management and Data Interpretation www.biorxiv.org/content/10.1101/202…
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Adam Cribbs @adamcribbs.bsky.social · 12/03/2025
We are pleased to share our latest preprint: "FlowAgent: A Modular Agent-Based System for Automated Workflow Management and Data Interpretation". FlowAgent makes complex bioinformatics workflows accessible and adaptive using agentic #AI. #Bioinformatics www.biorxiv.org/content/10.1...
biorxiv.org
FlowAgent: A Modular Agent-Based System for Automated Workflow Management and Data Interpretation
Reproducibility, automation, and flexibility remain persistent challenges in bioinformatics, where complex workflows require integration of diverse computational tools, rigorous quality control, and d...
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Reposted by Adam Cribbs
George Takei @georgetakei.bsky.social · 07/03/2025
Oooh! Oooh! I know! Mar-a-Lago.
A screenshot of an X post by Paul Graham (@paulg
) posted 13 hours ago on March 7, 2025, asking which American Republican leaders are bold enough to respond to a question posed by Inna Sovsun (@InnaSovsun
). Inna Sovsun's post challenges those suggesting Ukraine give up Crimea and Donbas for peace by asking them to name a specific region in their own country they would surrender if Putin started bombing their cities.
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Adam Cribbs @adamcribbs.bsky.social · 16/02/2025
Bit late, but first paper of 2025. 🧬Enhancing #singlecell #transcriptomics: Our recent study introduces an interposed anchor strategy to improve gene expression profiles in droplet-based single-cell sequencing analyses. www.nature.com/articles/s42...
nature.com
Enhancing single-cell transcriptomics using interposed anchor oligonucleotide sequences - Communications Biology
Droplet-based sequencing is key to single-cell transcriptomics but faces challenges from bead synthesis errors. A new bead design with anchor sequences improves UMI identification, read recovery, and ...
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Reposted by Adam Cribbs
Alessandro Rigolon @alerigolon.bsky.social · 10/02/2025
I was just told that I have to remove “climate” from the title of an ongoing grant if I want to keep it. And publications from that grant cannot include “climate” and other forbidden words. I can’t believe I’m writing this from the United States of America. #AcademicSky
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Reposted by Adam Cribbs
Communications Biology @commsbio.nature.com · 17/01/2025
Droplet-based sequencing is key to single-cell transcriptomics but faces challenges from bead synthesis errors. A new bead design with anchor sequences improves UMI identification, read recovery, and feature detection for both short- and long-read methods. www.nature.com/articles/s42...
nature.com
Enhancing single-cell transcriptomics using interposed anchor oligonucleotide sequences - Communications Biology
Droplet-based sequencing is key to single-cell transcriptomics but faces challenges from bead synthesis errors. A new bead design with anchor sequences improves UMI identification, read recovery, and ...
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