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Acta Neuropsychiatrica

@actaneuropsych.bsky.social
340 followers 1.1K following 202 posts

An International Journal of Translational Neuropsychiatry www.cambridge.org/core/journals/act…

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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 03/08/2026
What are the relationships between childhood trauma, inflammation, metabolic health, and mental health in a community sample of adults? @gemmawallace.bsky.social @lkaychicago.bsky.social brickphd.bsky.social et al., showed that: #ChildhoodTrauma #MentalHealth #Inflammation #MetabolicHealth
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 03/08/2026
🧠 Can neuropsychological tasks improve our understanding of depression and anxiety in adolescents? A recent scoping review examined the use of three widely used paradigms: • Emotional Go/No-Go (EGNG) • Delay Discounting Task (DDT) • Balloon Analogue Risk Task (BART)
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 08/06/2026
A 25-year longitudinal birth cohort study from Estonia reveals how genes, biomarkers, environment, and family shape behavior, mental health, and life trajectories. Findings offer key insights into neurodevelopment, psychiatric risk! @neuropsychochem.bsky.social doi.org/10.1017/neu....
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Insights into neuroscience from the representative birth cohort samples of a multidisciplinary longitudinal study | Acta Neuropsychiatrica | Cambridge Core
Insights into neuroscience from the representative birth cohort samples of a multidisciplinary longitudinal study - Volume 38
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 26/04/2026
Some papers carry more than scientific weight: they carry legacy. This study honors a deeply respected contributor to Acta Neuropsychiatrica and a leading figure in psychiatry, whose impact continues to shape the field. doi.org/10.1017/neu....
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 28/03/2026
How effective are music-based interventions for mental health in young adults? In this systematic review of clin trials in young adults, found that music therapy, binaural beats & rhythm-based auditory stimulation are associated w/ moderate improvements across multiple domains:
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 06/02/2026
🧠🧬 Autoimmunity as an underexplored contributor to neuropsychiatric symptoms in 22q11.2 deletion syndrome A recent study synthesizes evidence linking autoimmune processes to the neuropsychiatric phenotype observed in 22q11.2 deletion syndrome (22q11DS).
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 23/01/2026
How prevalent are behavioural addictions among adolescents? A newly published study in Acta Neuropsychiatrica suggests insights by examining multiple behavioral addictions simultaneously.
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 10/01/2026
Decision-making in Borderline Personality Disorder (BPD) in Social Context A recent fMRI study publishe in Acta Neuropsychiatrica used a multi-round Ultimatum Game to examine fairness, norm violations, and value processing in individuals with BPD. #fMRI #SocialCognition
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 22/12/2025
As we approach the end of 2025, we would like to send a warm thank you to the entire Acta Neuropsychiatrica community —our dedicated authors, diligent reviewers & committed editorial board members. On behalf of the Acta Neuropsychiatrica and the board of the SCNP.
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 19/12/2025
🧩Exosomes: A New Frontier in Understanding & Treating Autism Spectrum Disorder (ASD) How can they advance ASD research?
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 05/12/2025
🌍 From nomadic origins to modern stress: what can birds teach us about mental health? doi.org/10.1017/neu....
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 21/11/2025
🧠 Could psychedelics help rewire the brain–body disconnect? 💊 + 🧍‍♀️A new pilot study explores this question by investigating psilocybin-assisted therapy in Motor Functional Neurological Disorder (FND), pairing pharmacological and rehabilitative approaches.
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 07/11/2025
🩺 Building Early Pain Literacy Pain-related knowledge can improve quality of life and satisfaction, and the sooner the better ✨In a new study, a pain neuroscience education (PNE) program significantly improved outcomes in adolescents with and without intellectual disabilities.
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 27/10/2025
🍄 What does the evidence say on Psilocybin Therapy in Depression? 📄 A new PRISMA-guided systematic review analyzed 22 clinical studies, including randomized controlled + open-label trials. Populations included treatment-resistant depression and varied dosing and adjunctive protocols
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 24/10/2025
🧩 Rethinking Schizophrenia Emerging evidence suggests schizophrenia has 2 biologically distinct forms: 🔹 Major Neurocognitive Psychosis (MNP) 🔹 Simple Neurocognitive Psychosis (SNP) Both differ in immune and metabolic pathways, especially in how the brain processes tryptophan (TRP)
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 17/10/2025
Navigating the Use of Xanomeline/Trospium (Cobenfy/KarXT) KarXT marks a significant shift as the first muscarinic Our latest paper breaks down the key patient profiles that may benefit most from this novel mechanism of action: doi.org/10.1017/neu....
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 10/10/2025
🎤 Voice over for measuring the physiological stress response. What if the speech could be used as a digital biomarker of stress? Using a validated stress-induction paradigm, researchers analyzed vocal features in relation to salivary cortisol and state anger.
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 25/09/2025
Is Clozapine use hindered?🚧A recent paper sheds light on how to transform care for treatment-resistant schizophrenia Clozapine initiation and maintenance are hampered by misconceptions about side effects and monitoring (e.g., hospitalization/frequent tests) 🩺📋, despite confidence in the guidelines
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 19/09/2025
🔬Molecular Mechanisms of Amisulpride New cell study reveals the complex molecular footprint of the antipsychotic amisulpride. 📊Scientists treated neuroblastoma cells with amisulpride and discovered it changes the levels of key genes and proteins involved in:👇
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 10/09/2025
📢Exciting news #CINP2026 in Glasgow will be a Joint Meeting of the Scandinavian College of Neuropsychopharmacology (SCNP) + the International College of Neuropsychopharmacology! Join us for this unique event which promises to be an outstanding meeting of science & collaboration @ijnp.bsky.social
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 05/09/2025
💊GLP-1 Agonists & Opioid Abuse New translational work examines whether GLP-1 receptor agonists(GLP-1 RAs) could support treatment and/or prevention in people living with opioid use disorder(OUD) 🛡️Early evidence suggests GLP-1 RA administration was linked to reduced risk of opioid overdose in humans
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 29/08/2025
🧠✨ Psychedelics & the Neuroimmune System A new review in Acta Neuropsychiatrica explores how 5-HT2A receptor psychedelics interact with the immune system, and how this interplay may also drive neuronal changes.
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 22/08/2025
🚨 Could AI Chatbots Worsen Mania in Bipolar Disorder? A striking editorial suggests that chatbots may mirror and amplify the elevated mood of users prone to mania, acting like a form of "emotional contagion." 🧠 Check the editorial at: doi.org/10.1017/neu.... #DigitalMentalHealth #AIRegulation
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 08/08/2025
🧩FGF19: Linking Smoke and Mental Health 🚬 Fibroblast growth factor 19 (FGF19) regulates a wide range of biological functions (energy homeostasis, proliferation, survival, and migration) and has an emerging role as an oncology target A recent study on FGF19 in depression and smoking revealed:
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 01/08/2025
🛤️ "The path is known by asking those who have walked it before." — Zulu proverb (South Africa) 🧠 This new study in Acta Neuropsychiatrica examined modifiable & non-modifiable factors linked to mental health changes during COVID-19.
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 22/07/2025
🌍🧠 #WorldBrainDay | July 22 Brain health is vital at every age. From early development to aging, protecting brain function improves lives globally. ➡ 1 in 8 people live with a mental disorder, often affecting cognition, emotion & behavior. #BrainHealthForAll #Neuropsychiatry
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 17/07/2025
A follow-up exome analysis of 270K UK #Biobank participants again found no gene-level associations with affective disorders. Even in severe cases needing specialist referral and in this large sample, rare variant effects are likely too small and spread across many genes.
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 11/07/2025
🧠Is Internet Search a Proxy for Treatment? No, we’re not talking about 🍕restaurants near the Pentagon. But in a similar way, Google Trends mirrors real-world ADHD prescription patterns Researchers found that in Scandinavia (2010–2023) search trends correlate w/ADHD prescriptions
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Attention-deficit hyperactivity disorder drug search trends: a Scandinavian perspective | Acta Neuropsychiatrica | Cambridge Core
Attention-deficit hyperactivity disorder drug search trends: a Scandinavian perspective - Volume 37
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 04/07/2025
🧠 😞 Late-Life Depression (LLD) LLD is shaped by a complex interplay of biological, psychological, and social factors + distinct clinical and biological features.
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 20/06/2025
EiC @wegener.bsky.social had the pleasure of welcoming the Associate Editor for the Special Content Section, Prof. Gin Malhi (University of Sydney), to the beautiful summer at Aarhus University.
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 27/05/2025
🧠New insights into the mechanism for the motor and #immune deficits of Kabuki syndrome Bapa mice show ↑striatal TH, GFAP, IBA-1—linking #dopaminergic hyperactivity & #neuroinflammation. The strain is a promising model to study motor & immune deficits doi.org/10.1017/neu....
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Behavioural impairments in a mouse model of Kabuki syndrome associated with dopaminergic and neuroinflammatory modulations | Acta Neuropsychiatrica | Cambridge Core
Behavioural impairments in a mouse model of Kabuki syndrome associated with dopaminergic and neuroinflammatory modulations - Volume 37
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 19/05/2025
🧠 Handling the Double-Edged Sword of Antipsychotics: Wielding Precision Psychiatry Antipsychotics like aripiprazole & risperidone are widely used—not just for psychosis but also mood & behavioral disorders. Yet, adverse effects may hinder outcomes. 🔄 #Psychiatry #Antipsychotics
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 09/05/2025
🧠 This review just published in Acta Neuropsychiatrica explores how institutionalization in residential care affects children's brain development and mental health, through an electrophysiology perspective. The authors found that:
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 30/04/2025
Can ACT Help Reduce Suicidality? This new systematic review and meta-analysis examined the effectiveness of Acceptance and Commitment Therapy (ACT) on suicidality, including suicidal ideation and attempts. And the authors found that:
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Reposted by Acta Neuropsychiatrica
Gregers Wegener @wegener.bsky.social · 24/04/2025
Please read this important Editorial from BJPsych, written by 22 Journal Editors of Scientific Psychiatic Journals. doi.org/10.1192/bjp.... @actaneuropsych.bsky.social #MentalHealthResearch #ScienceIntegrity #AcademicFreedom #MentalHealthPolicy #ScientificTruth
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Truthful communication of mental science: pledge to our patients and profession | The British Journal of Psychiatry | Cambridge Core
Truthful communication of mental science: pledge to our patients and profession
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 25/04/2025
🧠🩺 Can #preeclampsia (PE) be addressed by assessing behavioral and metabolic changes? A new study published in Acta Neuropsychiatrica provides evidence that neuropsychiatric symptoms in PE may be linked to immune and metabolic biomarkers. ✅Top 3 #biomarkers identified, with highlights to:
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 15/04/2025
🧠 Mild Behavioral Impairment (MBI) is a challenging sign in dementia, impacting patients, families, and clinical management. Its early manifestation can be associated with faster cognitive decline and poorer prognosis. 🕵️‍♂️ How can we improve risk profiling in patients? 👇
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 09/04/2025
Another one on GLP-1 receptor agonists (GLP-1RA) — Could they be a new avenue for alcohol use disorder (AUD) treatment? 🍷🚫 This recent review explored the potential of GLP-1RAs (like liraglutide/semaglutide) in modulating alcohol-related behaviors in both preclinical and clinical studies.
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 04/04/2025
🧠 GLP-1 Receptor Agonists: A new frontier in mental health treatment? 📚 This systematic review from McIntyre group explores whether GLP-1 receptor agonists (GLP-1 RAs) influence molecular and cellular systems implicated in neurogenesis and...
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 28/03/2025
🧠 Do commonly prescribed SSRIs—sertraline, citalopram, and escitalopram—affect osteoporosis risk? 🦴 This large-scale target trial emulation using real-world data set out to answer that question⬇️
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 14/03/2025
New Research Alert! 🧠🚨 Could neuroinflammation be a key player in ADHD? This study published by Eren-Kocak group explores the impact of perinatal nicotine exposure (PNE) on neurodevelopment. Findings reveal PNE triggers neuroinflammatory signaling in the PFC, leading to:
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 05/03/2025
🧠 Nutraceuticals in Mental Health A recent study published by the Bjørke-Monsen group compared folate and vitamin B12 levels in patients admitted to a psychiatric acute unit (n=981) with controls (primary health care; n=32201) – and the findings are interesting!⬇️
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 03/03/2025
🧬Important Insights into Lewy Body Dementia (LBD)! 🧠The study "Transcriptome-wide Alternative Splicing and Transcript-level Differential Expression Analysis of Post-mortem Lewy Body Dementia Brains" provides significant advances in understanding the molecular mechanisms underlying LBD.
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 21/02/2025
🧠 Recent investigation underscores the potential of non-pharmacological treatments in #psychiatry such as #exosomes, #miRNAs, #stemcell, #mitochondria transfer, #exercise therapy, or #transcranial stimulation. 📌↘️ @altmetric.com @cambridgeup.bsky.social
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 12/02/2025
✨ Innovation on Comprehensive Analysis in Mental Illness - New Advanced Bibliographic Revision Method! 🔍📚 Drs Chen and Ding employed this new comprehensive analysis method capable of analyzing >12,000 papers, far exceeding the capacity of trad tools like VOSviewer @altmetric.com
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 08/02/2025
🧠Does the #immunesystem play a role in accelerated aging in #Schizophrenia (SCZ) and #bipolar disorders (BD)? 🧬 Dr Steen group investigated the link between #telomere length (TL) and plasma levels of 12 immune markers to understand aging in SCZ and BP.
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 31/01/2025
🚨🧠💪 How does the drive for rewards shape health across adolescence and young adulthood? This fascinating longitudinal study investigated the link between reward sensitivity, physical activity, and metabolism. 🧵 #HealthScience #Metabolism #MentalHealth #Fitness #Neuroscience #Reward @altmetric.com
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 24/01/2025
📢 More interesting results on GLP-1 agonist therapy! The recent preclinical data published in Acta Neuropsychiatrica highlights the importance of guiding #GLP-1agonist treatments with robust evidence. 🌟 Key Findings ⬇️ @altmetric.com @cambridgeup.bsky.social
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Acta Neuropsychiatrica @actaneuropsych.bsky.social · 21/01/2025
Looking for a home to your paper on #Psychopharmacology or #Immunopsychiatry? Look no further! Final submissions are due February 1st on the Journal submission site. Check the guide for authors on: cambridge.org/core/journal...
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Reposted by Acta Neuropsychiatrica
Institute of Psychiatry, Psychology & Neuroscience @kingsioppn.bsky.social · 15/01/2025
NEW research by IoPPN (@cathrynlewis.bsky.social) and @edinburghuni.bsky.social (Andrew McIntosh) researchers have identified new genetic risk factors for #depression across all global populations for the 1st time, in study in Cell Read more: www.kcl.ac.uk/news/global-...
kcl.ac.uk
Global study pinpoints genes for depression across ethnicities
Researchers at King's College London and University of Edinburgh have identified new genetic risk factors for depression across all major global populations for the first time, allowing scientists to predict risk of depression regardless of ethnicity.
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