Reposted by Abdou HachaniASM @asm.org · 05/03/2026Metabolic versatility in carbon source usage, iron transport and resistance to oxidative stress is interlinked and central to S. aureus fitness in serum, representing potential S. aureus vulnerabilities that could be exploited therapeutically. #mSystems; asm.social/2Q8 135
Abdou Hachani @abdou-hachani.bsky.social · 24/11/2025So great to catch up with my incredible mentor and friend Alain Filloux @fillouxlab.bsky.social in Melbourne. #Bacteriology #T6SS #Pseudomonas #Biofilm 030
Reposted by Abdou HachaniAnimalcules @bacteriophile.bsky.social · 21/09/2025www.nature.com/articles/d41... #MicroSkynature.comWorld’s first AI-designed viruses a step towards AI-generated lifeScientists used AI to write coherent viral genomes, using them to synthesize bacteriophages capable of killing resistant strains of bacteria. 113
Reposted by Abdou HachaniTania Wong @taniawong.bsky.social · 01/08/2025Pleased to share our latest study @natcomms.nature.com! We show that the host metabolites fumarate and itaconate impose selective pressure on Staphylococcus aureus, driving its adaptation via the enzyme FumC. Grateful to all who contributed to this work! www.nature.com/articles/s41...nature.comRegulation of airway fumarate by host and pathogen promotes Staphylococcus aureus pneumonia - Nature CommunicationsThis study reveals how the pathogen Staphylococcus aureus adapts to the lung microenvironment, rich in host metabolites fumarate and itaconate, by using a key enzyme, FumC, to support its metabolic fi... 02611
Reposted by Abdou HachaniTung Le @tunglejic.bsky.social · 09/05/20251/ Excited to share our latest work on gene transfer agents (GTAs) in Caulobacter crescentus, led by Emma Banks in collaboration with Pavol Bardy and Mai Nguyen from York!!! See a brief thread below. shorturl.at/o6S1wshorturl.atA bacterial CARD-NLR immune system controls the release of gene transfer agentsBacteria have evolved a wide array of immune systems to detect and defend against external threats including mobile genetic elements (MGEs) such as bacteriophages, plasmids, and transposons. MGEs are ... 28738
Reposted by Abdou HachaniTania Wong @taniawong.bsky.social · 19/04/2025Excited to share our preprint demonstrating how fumarate metabolism by host and pathogen promotes pneumonia! Itaconate synergizes with fumarate, driving staphylococcal adaptation for survival. Check it out!👇 www.biorxiv.org/content/10.1...biorxiv.orgRegulation of airway fumarate by host and pathogen promotes S. aureus pneumoniaStaphylococcus aureus is a leading cause of healthcare-associated pneumonia, contributing significantly to morbidity and mortality worldwide. As a ubiquitous colonizer of the upper respiratory tract, ... 0123
Reposted by Abdou HachaniTracy Palmer @proftracypalmer.bsky.social · 09/04/2025Two ERC-funded postdoc positions available in the team - one here and second to follow - please repost! jobs.ncl.ac.uk/job/Newcastl...jobs.ncl.ac.ukResearch Associate Genetic and functional analysis of Gram positive secretion systems and substratesResearch Associate Genetic and functional analysis of Gram positive secretion systems and substrates 13169
Abdou Hachani @abdou-hachani.bsky.social · 01/12/2024Pushing the boundaries of Nanopore technology while opening new avenues in AMR research. Amazing work from @evamarianovoa.bsky.social 020
