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Biohub

@biohub.org
3.1K followers 108 following 80 posts

Combining frontier AI & frontier biology to help scientists cure or prevent disease

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Biohub @biohub.org · 24/09/2026
Biohub Investigator @jameszou.bsky.social built a “virtual biotech”—37K AI agents that analyzed 57K clinical trials and found clues to what makes drugs succeed. The New York Times traces its roots to a collaboration sparked by our scientist John Pak: bit.ly/4hLrpnm
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Biohub @biohub.org · 02/09/2026
🔬New in @cellpress.bsky.social from Biohub Investigator Bo Huang: AI-designed proteins built from scratch (dubbed "Rhobins") work in living cells and now match or even surpass fluorescent tags refined over decades of natural protein engineering. Read the paper: www.cell.com/cell/fulltex...
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Biohub @biohub.org · 01/09/2026
Organoids can mimic human organs, but we study them mostly with static, endpoint assays. A new perspective argues for instrumented tissues, which are engineered human tissue woven with electrical, chemical, mechanical, and optical sensor arrays, to move faster from disease mechanism to therapy.
Diagram of instrumented 3D tissue receiving multimodal optical, electrical, and chemical stimuli, sending data to a laptop for AI reasoning.
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Biohub @biohub.org · 06/08/2026
Proteins are the machinery of life. Scientists have cataloged billions of protein sequences—but their biology is still mostly unknown. ESM Atlas is a new way in. bit.ly/4dJcF6G
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Biohub @biohub.org · 03/08/2026
🎉 Congrats to Scott Fraser, Biohub’s President of Dynamic Imaging, on receiving the Microscopy Society of America’s Distinguished Scientist Award - Biological Sciences, in recognition of his transformative contributions in bioimaging and molecular analysis!
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Biohub @biohub.org · 16/07/2026
🚨 New preprint: We reprocessed 77k zebrafish RNA-seq datasets from across the global research community and found hidden viruses in 10% of them—including a fish virus whose proteins are 91% identical to human Influenza B—then built a generalizable pipeline. bit.ly/4vxFF72
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Biohub @biohub.org · 02/07/2026
🎉Congrats to the Remoscope team, 1st place winner of the Medical Device category of the Nebius AI Discovery Awards! Developed at Biohub, Remoscope is an AI-powered diagnostic platform that can rapidly image and analyze blood and other biological fluids to diagnose disease.
Three men sitting at a table hold a large prize check for $100,000 at the AI Discovery Awards 2026 event, with other attendees visible in the background.
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Biohub @biohub.org · 29/06/2026
How do you track thousands of cells in complex systems, in 3D & over time? We are launching a Kaggle challenge to push the frontier of AI-powered cell tracking, building on advances like Ultrack & the DaXi lightsheet microscope from the @loicaroyer.bsky.social lab. bit.ly/4bfdzWE
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Biohub @biohub.org · 29/06/2026
What happens when physicists turn their tools on living systems? That's the question at the heart of the Physics of Life Symposium—and this year marks its fifth edition. Submit an abstract or register to attend by Aug. 14: bit.ly/4xJIPH7
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Biohub @biohub.org · 22/06/2026
The 2nd Chicago BioEngineering Conference (CBEC) is back — Sept. 17–18 in downtown Chicago! 🧬 Omics. Bioelectronics. AI × bio. A stellar speaker lineup. Two days of science that matters. Space is limited → register now: bit.ly/4vqlXLj
Promotional card for the 2nd Chicago BioEngineering Conference (CBEC), September 17–18, 2026, at the Sheraton Grand Chicago Riverwalk
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Biohub @biohub.org · 16/06/2026
Cryo-ET gives unparalleled views of cellular structures, but targeted sample preparation by cryo-FIB milling has been a constraint. No longer! A new workflow yields close to 100% targeting success for centrioles & other small structures. Read the preprint ⤵️ www.biorxiv.org/content/10.6...
Diagram of FIB-SEM with integrated fluorescence microscope alongside cryo lamella micrograph and 3D segmentation highlighting targeted centrioles
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Biohub @biohub.org · 12/06/2026
Check out Alex Rives on Latent Space discussing the science behind ESMFold2, ESMC, and ESM Atlas, and what a world model of protein biology actually makes possible. 🎙️ bit.ly/4vwqLy3
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Biohub @biohub.org · 12/06/2026
The laser phase plate is leveling up cryoEM so we can see biology like never before. Learn more: bit.ly/4vK9LVn
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Biohub @biohub.org · 11/06/2026
In a series of 3 papers and preprints, we’re thrilled to share with you the working laser phase plate. In collaboration with research led by Holger Müller at UC Berkeley, this is a huge innovation in imaging to make small and faint objects inside cells visible. bit.ly/4vK9LVn
Waves of laser light coming from four different directions and meeting in the middle brightly inside the cavity of the laser phase plate
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Biohub @biohub.org · 04/06/2026
Better vitrification = better cryo-ET. We've opened an RFA for two-year grants to advance vitrification techniques for biological samples—welcoming applications from researchers in heat transfer, cryogenics, and materials science. Apply here: bit.ly/4uip6eJ
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Biohub @biohub.org · 27/05/2026
Proteins are the machinery of life. Billions of their sequences have been cataloged—but the biology behind most is still unknown. Today we're releasing ESMFold2, ESMC and ESM Atlas to help change that. Open source, open to every scientist. biohub.ai/esm/protein
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Biohub @biohub.org · 19/05/2026
Inflammation drives nearly every major disease—cancer, heart disease, and autoimmune conditions. Yet we've never been able to watch it progress in living tissue. We're funding 15 projects to build real-time molecular tools to change that. Learn more ➡️ bit.ly/4wFDJej
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Biohub @biohub.org · 24/04/2026
On the cover of @cp-cellbiomat.bsky.social! New study by Kangfu Chen, Danile Wang, Shana Kelly uses omics/engineering tools to better understand how tissues and cells behave in vivo, advancing both fundamental biology and better treatment options for cancer.
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Biohub @biohub.org · 06/04/2026
The 2nd Chicago BioEngineering Conference (CBEC) is coming! We have a stellar lineup of speakers and sessions on omics, bioelectronics & AI × bio. See you in downtown Chicago Sept. 17-18! Space is limited — register early. Learn more ➡️ biohub.org/event/chicag...
card with event title, dates, location (Sheraton Grand Chicago Riverwalk)
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Biohub @biohub.org · 01/04/2026
We’re thrilled to welcome 11 new investigators—visionary scientists from @columbiauniversity.bsky.social, @rockefeller.edu & Yale University who will pursue ambitious, high-impact research and contribute to our Immune Cell Reprogramming work. Learn more ➡️ biohub.org/news/investi...
headshots of Greg Alushin, Rockefeller; Julien Berro, Yale; Rong Fan, Yale; Richard Flavell, Yale; Emily Mace, Columbia; Maksim Mamonkin, Columbia; Michel Nussenzweig, Rockefeller; Jeffrey Ravetch, Rockefeller; Kenneth Shepard, Columbia; Samuel Sternberg, Columbia; Andrew Wang, Yale
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Biohub @biohub.org · 18/03/2026
Cell Biology at Scale (CB@S) is coming to Europe for the first time! 🇸🇪 Join @scilifelab.se & Biohub for a one-day symposium on multimodal data, AI-driven modeling & the future of cell biology. 📍 Stockholm, Sweden | June 3, 2026 Learn more: bit.ly/4cTXIib
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Biohub @biohub.org · 11/03/2026
What if the key to better mRNA therapies wasn't redesigning the delivery vehicle—but feeding the cell? A new study from Daniel Wang & @shanakelley.bsky.social describes a surprising solution to a stubborn problem. Read more ➡️ bit.ly/3MXj7MT
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Biohub @biohub.org · 05/03/2026
New in Nature Immunology: @rohamparsa.bsky.social & @danmucida.bsky.social / @rockefeller.edu reveal that where a T cell gets activated shapes what it becomes, foundational to our mission of programming immunity for early disease detection. Read more ▶️ biohub.org/blog/track-t...
Illustration showing how T cells, when activated, turn on a red fluorescent protein and migrate through the bloodstream to three organs - lungs, lymph node, spleen – taking on different roles in different tissues.
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Biohub @biohub.org · 28/02/2026
🩷💚💙💜 We stand in solidarity with the rare disease community worldwide. On #RareDiseaseDay, we light up our offices to honor patients, families, clinicians, and researchers advancing understanding and care.
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Biohub @biohub.org · 27/02/2026
That's a wrap on our AI Applications in Biology Symposium. Grateful to our keynotes, Nikos Hatzakis, @martinsteinegger.bsky.social, Xinyi Zhang, and all presenters for an inspiring day of explorations at the crossroads of machine learning and biological discovery.
5 people posted on stage with a slide behind them that reads "AI Applications in Biology Symposium"Speaker standing on stage next to a podium
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Biohub @biohub.org · 25/02/2026
🧵Antibiotic resistance is a public health crisis. But viruses called phages have been solving this problem for millennia. New research in @nature.com reveals how 3 different phages attack the same weak spot—a protein called MurJt—potentially leading to a new class of antibiotics.
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Biohub @biohub.org · 11/02/2026
And also celebrating Adam de la Zerda from the Biohub Investigator Program on the #TIME100 Health List, who has pioneered work in molecular imaging technologies. Read more ➡️ bit.ly/4awNyRP
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Biohub @biohub.org · 11/02/2026
🎉 Biohub Investigator @pascalge.bsky.social has been named to the 2026 #TIME100 List of the World’s Most Influential Leaders in Health for his groundbreaking epidemiological studies showing how a shingles vaccine lowers risks of developing dementia. Check it out ➡️ bit.ly/4rN5Gh7
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Biohub @biohub.org · 28/01/2026
Modern imaging + AI are changing how biologists study living systems. What’s driving the shift? Better imaging hardware, mature computational infrastructure, and tighter collaboration between experimentalists and AI modelers. bit.ly/4r778L0
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Biohub @biohub.org · 08/01/2026
How close are we to programmable human cells? A new @cellpress.bsky.social perspective from Martha Gillette and Yogesh Goyal explores how synthetic biology & AI are enabling precise control over cell behavior, opening new paths for drug development and personalized therapies. bit.ly/48Mx1JO
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Biohub @biohub.org · 05/01/2026
WaveOrder is a powerful new #microscopy tool from Biohub that helps researchers reconstruct messy microscope data into clean, quantitative maps. It’s grounded in physics & it’s already changing how we see biology. 📚 Preprint bit.ly/4jgDJLB 🔬WaveOrder: czi.co/4pMwGgb
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Biohub @biohub.org · 12/12/2025
🧪 That's a wrap on #CellBio2025! We had a blast in Philly connecting with the cell biology and imaging communities, and sharing our open-access tools!
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Biohub @biohub.org · 04/12/2025
It’s our favorite time of year - hot cocoa & #CellBio2025! Come find us at booth 301 and see some of our latest tools for capturing novel biological insights across scales.
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Biohub @biohub.org · 03/12/2025
📍#NeurIPS2025! Stop by booth #833 to explore AI-powered tools pushing biology forward: 🧬VariantFormer—predicts how genetic variants affect gene expression 💡scLDM—simulates single-cell data on demand for virtual experiments 🔬ESMC + ESM3—foundational models for protein structure, function & evolution
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