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Ziheng Yang Lab

@zihengyang.bsky.social
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Ziheng Yang's Lab at UCL (CLOE) | Computational Molecular Evolution Website: abacus.gene.ucl.ac.uk BPP GitHub: github.com/bpp PAML GitHub: github.com/abacus-gene/paml PAML discussion group: groups.google.com/g/pamlsoftware

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Ziheng Yang Lab @zihengyang.bsky.social · 10/09/2026
🎉 Congratulations to Ziheng Yang and Rasmus Nielsen, joint recipients of the 2026 Balzan Prize for Molecular Evolution: Decoding Patterns of Genomic Change 🎉 To mark the occasion, we all went out for a celebratory lab lunch! 🥳 www.balzan.org/en/evoluzion...
The Yang Lab celebrated Ziheng's Balzan Prize while having a lovely lunch together! Right side of the table, front to back: Ziheng Yang, Tomas Flouri, Jiayi Ji. Left side of the table, front to back: Sandy Álvarez-Carretero, Zihui Yuab, Ana Serra Silva.
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Sandra Álvarez @sabifo4.bsky.social · 08/09/2026
Keen on learning how to use Bayesian model selection to test different hypotheses of diversification? 🦴🧬🕰️ Check our latest work in Molecular Biology and Evolution! academic.oup.com/mbe/article/... With @zihengyang.bsky.social, @phil-donoghue.bsky.social, and @mariodosreis.bsky.social 💫 (1/2)
academic.oup.com
On the origin of animals and placental mammals: a critique of literalist readings of the fossil record
Abstract. The fossil record is incomplete, as evidenced by the pervasive presence of ghost lineages throughout the Tree of Life. For example, across placen
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Philip Donoghue @phil-donoghue.bsky.social · 19/12/2025
Pre-Christmas moleclular-clock shenanigans with @sabifo4.bsky.social @mariodosreis.bsky.social @zihengyang.bsky.social
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Physalia-courses@ONLINE @physaliacourses.bsky.social · 05/12/2025
Huge shoutout to the amazing instructor squad @kaplipa.bsky.social , @sabifo4.bsky.social , Tomas Flouri & @zihengyang.bsky.social for smashing another epic #Phylogenomics course! 🚀 Massive thanks to everyone who joined us this week — go crush your data and rock those projects! 💥🔥
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Physalia-courses@ONLINE @physaliacourses.bsky.social · 01/12/2025
Very happy to kick off the 5th edition of the #Phylogenomics course with @kaplipa.bsky.social , Tomas Flouri, @sabifo4.bsky.social , @zihengyang.bsky.social , and a wonderfully diverse cohort of attendees from all around the globe!
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Ziheng Yang Lab @zihengyang.bsky.social · 25/11/2025
Wrapping up our annual joint lab meeting with a visit to the Grant Museum of Zoology at UCL was such a highlight! Always inspiring to reconnect with longtime colleagues, new team members, and collaborators💫
Ziheng Yang's and Mario dos Reis' research groups, and visitors, at the Grant Museum of Zoology at University College London. Left to right: Jiayi Ji, Chi Zhang, Yuttapong Thawornwattana, Lucas Freitas, Zihui Yang, Ziheng Yang, Yuqing Peng (bottom), Siri Olsen (top), Laura Mulvey, Mario dos Reis (bottom), Asif Tamuri (top), Sandra Álvarez-Carretero.
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Ziheng Yang Lab @zihengyang.bsky.social · 11/11/2025
We have had a great time at the Workshop on Computational Genomics at Beijing Normal University! Thank you to all organisers, course assistants, and the fantastic and hard-working participants for making this event possible! 下次见, 谢谢 🌹(1/2)
Workshop on Computational Genomics at Beijing Normal University (Nov 6th - 7th 2025) | Group pictureWorkshop on Computational Genomics at Beijing Normal University (Nov 6th - 7th 2025) | Co-organisers Ziheng Yang and Dayong Zhang with participant and course assistant Cai-jin ChenWorkshop on Computational Genomics at Beijing Normal University (Nov 6th - 7th 2025) | IntroductionsWorkshop on Computational Genomics at Beijing Normal University (Nov 6th - 7th 2025) | From left to right: Sirui Cheng (instructor), Yuttapong Thawornwattana (instructor), Tomas Flouri (instructor), Jie Han (co-organiser), Sandra Álvarez-Carretero (instructor), Xiyun Jiao (instructor), Ziheng Yang (co-organiser and instructor)
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Ana Serra Silva @anaserrasilva.bsky.social · 29/09/2025
First up we have Xiyun Jiao and @zihengyang.bsky.social showing the importance of moving beyond model fit testing and embracing sensitivity testing in phylogenetics. In other words, question your data assumptions and test for model robustness not just adequacy. (2/n) doi.org/10.1093/evol...
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On measures of influence and discordance in phylogenomic analyses
Abstract. As models are approximate descriptions of real biological processes, and data are collected often with errors and contamination, sensitivity or r
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Molecular Biology and Evolution @molbioevol.bsky.social · 19/08/2025
Ji, Kapli, Flouri & @zihengyang.bsky.social assess the impact of genotyping errors in phylogenomic data on Bayesian inference of species trees, suggesting that it is better to sequence a few samples at high depths over many samples at low depths. 🔗 doi.org/10.1093/molbev/msaf184 #evobio #molbio
doi.org
The Impact of Sequencing and Genotyping Errors on Bayesian Analysis of Genomic Data under the Multispecies Coalescent Model
Abstract. The multispecies coalescent (MSC) model accounts for genealogical fluctuations across the genome and provides a framework for analyzing genomic d
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Society for Molecular Biology and Evolution @official-smbe.bsky.social · 20/07/2025
In the first Plenary speech of #SMBE2025, Ziheng Yang (@zihengyang.bsky.social) taught us quite a few improbable things on gene flow. We wish you a delicious breakfast for tomorrow, while mulling over these lessons... 😉
Ziheng Yang, SMBE2025 - Six impossible things to believe before breakfast, about gene flowZiheng Yang, SMBE2025 - Six impossible things to believe before breakfast, about gene flowZiheng Yang, SMBE2025 - Six impossible things to believe before breakfast, about gene flowZiheng Yang, SMBE2025 - Six impossible things to believe before breakfast, about gene flow
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Molecular Biology and Evolution @molbioevol.bsky.social · 01/07/2025
Using simulations and empirical data, Thawornwattana, Flouri, @wtf-r-species.bsky.social & @zihengyang.bsky.social ‬ et al. evaluate the performance of the MSC-M model for inferring gene flow. 🔗 doi.org/10.1093/molbev/msaf121 #evobio #molbio #geneflow
doi.org
Inference of Gene Flow between Species from Genomic Data When the Mode, Direction, and Lineages are Misspecified
Abstract. Thanks to genomic data, interspecific gene flow is increasingly recognized as a major evolutionary force that shapes biodiversity. Two models hav
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Society for Molecular Biology and Evolution @official-smbe.bsky.social · 23/06/2025
The first Keynote speech of #SMBE2025 will be given by SMBE's President Ziheng Yang (@zihengyang.bsky.social). "Six impossible things to believe before breakfast, about gene flow" 20.07.2025 | 18h00
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Ziheng Yang Lab @zihengyang.bsky.social · 06/06/2025
What a busy (but sunny) May in Crete!🔆 Ziheng & @sabifo4.bsky.social enjoyed teaching and meeting the participants at the Computational Molecular Evolution course! Ziheng then joined the satellite workshop on Biodiversity Genomics 🌍🧬 Thanks to everyone who made these fantastic meetings possible!!
Instructors and participants at the 2025 Computational Molecular Evolution course in Crete (group picture).Sandy teaching Bayesian node-dating analyses for timetree inference at the Computational Molecular Evolution course.Attendees joining the 2025 Satellite Workshop "Biodiversity Genomics: sample types, data, and tools to assess past, present and future biodiversity" in Crete (group picture)Ziheng's talk at the satellite workshop "Biodiversity Genomics: sample types, data, and tools to assess past, present and future biodiversity". Talk title: "Inference of between-species gene flow using genomic data"
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Ziheng Yang Lab @zihengyang.bsky.social · 02/05/2025
Congratulations Dr Jiayi Ji!! 🥳Thanks to examiners @hernanaburbano.bsky.social and Simon Martin, now time to enjoy the long weekend! 🎉
Post viva celebrations with Dr Jiayi Yi. Left to right: Hernán Burbano, Jiayi Ji, Simon Martins, and Ziheng Yang.Post viva celebrations with Dr Jiayi Yi. Jiayi holding one of his PhD presents: a PhD mug and a cute chipmunk plush.Post viva celebrations with Dr Jiayi Yi. Jiayi showing his new chipmunk plush.
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Systematics Association @systassn.bsky.social · 30/04/2025
And that's a wrap on the SystAssn-SRUK/CERU Bayesian Phylogenetics Workshop! Thank you to all the attendees, instructors (@anaserrasilva.bsky.social, @sabifo4.bsky.social, Tomas Flouri and Yuttapong Thawornwattana) and to our wonderful TA @lauramulvey.bsky.social!
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Ziheng Yang Lab @zihengyang.bsky.social · 01/05/2025
The 2nd day of the SystAssn-SRUK/CERU Bayesian Phylogenetics Workshop was focused on the Multispecies Coalescent Theory and the usage of BPP, led by our lab members Tomas Flouri and Yuttapong Thawornwattana! 💻🧬
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Ziheng Yang Lab @zihengyang.bsky.social · 30/04/2025
The SystAssn-SRUK/CERU Bayesian Phylogenetics Workshop started yesterday! During the 1st day, our lab members Tomas Flouri, @anaserrasilva.bsky.social, and @sabifo4.bsky.social had fun sharing their knowledge on Bayesian statistics, phylogeny inference & timetree inference with the participants💻🧬
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Ziheng Yang Lab @zihengyang.bsky.social · 06/03/2025
Our Workshop on Genomics at Sun Yat-sen University Institute of Advanced Studies Hong Kong has come to an end! We are grateful to all organisers and very pleased to have meet such fantastic and hard-working participants! 下次见, 谢谢 🌹(1/2)
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Ziheng Yang Lab @zihengyang.bsky.social · 19/02/2025
Our lab members @sabifo4.bsky.social, @anaserrasilva.bsky.social, Tomas Flouri, and Yuttapong Thawornwattana are teaching a two-day workshop on Bayesian Phylogenetics Workshop 💻🧬 Pre-register your interest to join this event before March 14th, do not miss the deadline! More details below 🔽
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Ziheng Yang Lab @zihengyang.bsky.social · 09/12/2024
Thinking of starting a PhD on Bayesian phylogenetics next October 2025 in London? 🎓 You may want to check the TREES project led by the dos Reis Lab on integrating morphology and genomes for timetree inference! 🦴🧬💻Project supervisors: @mariodosreis.bsky.social & Ziheng Yang. More info in link 🔽
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Physalia-courses@ONLINE @physaliacourses.bsky.social · 06/12/2024
Wrapping up an incredible 5-day course on #Phylogenomics with a fascinating lecture on Molecular-Clock dating of species divergence by @mariodosreis.bsky.social, followed by a hands-on session with @sabifo4.bsky.social 🧬🕰️ Huge thanks to all participants for an inspiring week!@zihengyang.bsky.social
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Physalia-courses@ONLINE @physaliacourses.bsky.social · 05/12/2024
Here’s the amazing Phylogenomics Group 2024 📸 Thank you to our incredible instructors for sharing their knowledge and making complex topics approachable and engaging! 🙌 And a big shoutout to all participants—Thanks for joining us this week🎉 @sabifo4.bsky.social @zihengyang.bsky.social
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Physalia-courses@ONLINE @physaliacourses.bsky.social · 04/12/2024
🚨 Exciting Day 3 Ahead! 🚨 Today, we’re honored to have one of the giants of Phylogenomics 🧬✨, @zihengyang.bsky.social, kicking off the day with two lectures on the Multispecies Coalescent Model. Day3 will continue with an hands-on session led by Paschalia Kapli and Tomas Flouri🚀
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Physalia-courses@ONLINE @physaliacourses.bsky.social · 04/12/2024
✨ Day 2 highlight! ✨ Tomas Flouri and @sabifo4.bsky.social delivered masterful lectures and an exceptional hands-on session on Bayesian inference in Phylogenomics. 🎓💡 Their expertise truly shone through! Excited for the insights Day 3 will bring—stay tuned! 🚀
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Ziheng Yang Lab @zihengyang.bsky.social · 02/12/2024
The Physalia Phylogenomics course has started today! Tomas and Paschalia are leading today's session -- now, they are going through the practical session to apply all the concepts they have taught this morning! 💻
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Ziheng Yang Lab @zihengyang.bsky.social · 29/11/2024
If you have ever wondered whether the PAML documentation could be more interactive... We have good news for you! The PAML GitHub repository has been updated and a fresh PAML Wiki is now available for you to navigate the PAML documentation! 📄💻 (1/n) github.com/abacus-gene/...
github.com
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PAML is a program package for model fitting and phylogenetic tree reconstruction using DNA and protein sequence data. Please report only **technical issues** on this repository (e.g., compiling, pr...
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Ziheng Yang Lab @zihengyang.bsky.social · 28/11/2024
Hello BlueSky! The Ziheng Yang Lab will be using this social account to post news about the software we develop, upcoming workshops, and general news in evolutionary biology and computational methods 💻🧬🦴 Keep an eye on this site, we will be posting some news soon!
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