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Yiğitcan Sümbelli

@ysumbelli.bsky.social
152 followers 239 following 28 posts

Combining 3D biofabrication with synthetic biology via artificial cells | PostDoc Biomed Eng TU Eindhoven | van Hest Lab | The Research Center for Materials Driven Regeneration

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Yiğitcan Sümbelli @ysumbelli.bsky.social · 6h
Akademisyenin Sosyal Medyası Akademisyenlerin sosyal medya kullanımı üzerine tartıştık bu yazıda.
52haftabilim.com
Akademisyenin Sosyal Medyası
Akademisyenlerin sosyal medya kullanımı üzerine tartıştık bu yazıda.
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 30/09/2026
Paper alert! We developed a method to prepare matrix-adhered polypeptide-based complex coacervates in a hydrogel, and 3D printed them with a laser-based approach, namely LIFT. We published our study in Small; you can read the paper via this link: onlinelibrary.wiley.com/doi/10.1002/... #coacervate
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 25/09/2026
Yay🎉 Manuscript got accepted for publication! We developed a matrix-adhered complex coacervation method for artificial/synthetic cell-embedded 3D bioprinting. It'll be out soon, cannot wait to share! #bioprinting #coacervate #artificialcell #syntheticcell #tissueengineering #biofabrication
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 09/06/2026
We developed an analysis method for tissue engineering related papers. Our first analysis with method_v1 showed the trends in the field, and now we're improving the model to do more in depth analysis. You can read a part of our first analysis here: 52haftabilim.wordpress.com/2026/05/06/r...
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Nature Portfolio @natureportfolio.nature.com · 23/05/2026
Scientific figures can strongly influence how research findings are interpreted. This ‘How to’ Comment article in Nature Human Behaviour outlines a practical strategy for creating figures that communicate clearly across audiences and scientific contexts. go.nature.com/3R00b1t #Academicsky 🧪
This is figure 1, which shows key steps in producing an effective scientific figure.
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 21/04/2026
New post on the blog! We discussed why artificial cells could be a good candidate to engineer artificial tissues. Click the link below, and translate the page! 52haftabilim.wordpress.com/2026/04/21/y...
52haftabilim.wordpress.com
Yapay hücrelerden yapay dokulara
Yapay hücre kullanarak doku mühendisliği yapabilir miyiz?
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 08/03/2026
Yay🎉 I won my first-ever poster prize at (possibly) the last conference I attended as a PhD candidate 😁 You can see the study I presented on my (prize winning 🙃) poster in the link below; I 3D printed organelles in synthetic cells. pubs.acs.org/doi/full/10....
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Vaughn Cooper @vscooper.micropopbio.org · 23/12/2025
This is totally worth 5 minutes of your time and probably should be in every biology class. Nature is awesome. neal.fun/size-of-life/
neal.fun
Size of Life
From an amoeba to a blue whale
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 19/12/2025
I was at Ghent to talk about our project where we use a special printer to pattern artificial cells at Imperial College London @imperialcollegeldn.bsky.social. It's a collaboration between me, Jorin, Rav, and Alex. Cannot wait to share the results! @ravinash.bsky.social @biopatternlab.bsky.social
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 02/12/2025
I chose drawing my own figures in this story. It takes way more time, but it also feels like I have more freedom. In addition, I must accept the fact that I sometimes cheat and get inspired by the figures from such softwares :) In the end, drawing figures is a major part of science, and it's fun!
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 02/12/2025
I think using the same software is a two sided story. It, indeed, brings the major risk of looking similar to what others have done, but it also helps to achieve a minimum visual quality standard. All of us must have seen such horrendous hard-to-understand figures. Now it's easier to draw better.
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 02/12/2025
It's an interesting short thread here, starting a discussion about how the scientific figures are becoming more and more monotonous due to everyone using the same scientific illustration softwares more often.
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 22/11/2025
Our latest paper is out! We froze complex multiphases in time to study them in coacervates! Check it out here: doi.org/10.1002/advs...
doi.org
Preservation of Complex Multiphase Architectures in Polymer‐Based Artificial Cells by Photo‐Crosslinking
Phase separation organizes cellular components, yet stabilizing such dynamic structures in artificial cells remains challenging. A photo-crosslinking approach is presented that prolongs the lifetime ....
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 06/11/2025
Check out our latest paper! We not only prepared artificial cells but also 3D printed artificial organelles inside of them. This is one of my favorite projects from my PhD, and I am so happy that I can share the published version now. pubs.acs.org/doi/10.1021/...
pubs.acs.org
Intracompartmental 3D Printing of Enzymatically Active Organelle Mimics
Introducing subcellular structures in artificial cells is a key step in mimicking the structure and role of organelles, which are instrumental in compartmentalizing cellular reaction networks. Despite...
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 31/10/2025
Getting an email in the early morning, saying that they accept your manuscript for publication is one of the greatest ways to start your day! 🥳
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 11/10/2025
The results of brain drain couldn't be more clear. One country's loss is another's win. www.nature.com/articles/d41...
nature.com
More than 30% of this century’s science Nobel prizewinners immigrated: see their journeys
The most common destination for eventual Nobel laureates in physics, chemistry and medicine since 2000 is the United States, Nature has found.
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Karolinska Institutet @ki.se · 06/10/2025
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for their groundbreaking discoveries concerning peripheral immune tolerance that prevents the immune system from harming the body 🧪 www.nobelprize.org/prizes/medic...
Photo: Cecilia Odlind
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 23/07/2025
Yingtong just published a very nice article, and I contributed to that with SEM micrographs! In the paper, he introduced a strategy to optimize the optical absorbance of organic photothermal agents (OPTA) by adjusting the morphology of polymer assemblies. Check it out here: doi.org/10.1021/jacs...
doi.org
Solvent-Induced Morphology Control of Polymer Assemblies with Improved Photothermal Features
Organic photothermal agents (OPTAs) are extensively utilized in applications such as therapy and imaging. However, enhancing their photothermal performance often depends on complex molecular designs, ...
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 22/07/2025
Ah well... I only post academic stuff but the passing of Ozzy Osbourne is significant enough to break that. Such a massive name...
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 09/07/2025
Writing a manuscript takes time, and organizing figures covers a large portion of that time. Each time I export a figure, a suffix is added indicating the number of previous versions. You see it's the 50th version of the same figure and I'm not even sure whether this will be the final version.
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Kavli Institute for Theoretical Physics @kitp-ucsb.bsky.social · 03/06/2025
Watch the latest Blackboard Lunch talk on "Liquid-liquid phase separations and condensates in and out of equilibrium" by Shura Grosberg (‪#NYU), from the ongoing #KITP Program: Physical Principles Shaping Biomolecular Condensates #biomol25 buff.ly/Qmu5521 🧪
youtu.be
Liquid-liquid phase separations and condensates in and out of equilibrium | Shura Grosberg (NYU)
The purpose of these Blackboard Talk lunches is for the science of one program to be explained to the other KITP program participants. These talks lead to cr...
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Aafke Gros @aafkegros.bsky.social · 23/05/2025
In the context of our @reviewcommons.org revision process, I'm happy to announce Microscopy Nodes v2.2.0! This packs lots of new fun features, including new color management 🌈, clearer transparency handling 🫥, custom default settings 🔧 and more! Preprint at doi.org/10.1101/2025...
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 02/05/2025
We attended the annual symposium of @synbionl.bsky.social #synbionl2025 with Madelief, and presented some cool stuff from our projects related to controlled formation of subcellular structures within our artificial cells. It was a fun day!
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Nature [Unofficial] @nature.com.web.brid.gy · 29/04/2025
nature.com
The do’s and don’ts of scientific image editing
Nature, Published online: 29 April 2025; doi:10.1038/d41586-025-01299-2 Acceptable image-editing practices are partly a matter of common sense. But researchers say journals and funders could help scientists by standardizing policies.
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 23/04/2025
I came here from a country where they were actively making it hard to do scientific research. Now, the Netherlands is doing a similar thing. They're ruining higher education actively and passively. Why do governments sabotage their future like this? Isn't the cost of such an act obvious?
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 20/04/2025
As a scientist, I have tattoos about my MSc and PhD theses, and I love them!
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 31/03/2025
Interestingly (!), they saw that when they paid the reviewers, the review quality did not get worse. It's good to see paying peer reviewers is under trial by some publishers. www.nature.com/articles/d41....
nature.com
Publishers trial paying peer reviewers — what did they find?
Two journals embarked on efforts to compensate reviewers, with different results.
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Dennis Hazelett @vigocarpathian.bsky.social · 17/03/2025
I wrote something... about writing. #ScientificWriting to be exact, but I think it applies to all kinds of #writing.
rdcu.be
An open letter to graduate students and other procrastinators: it’s time to write
Nature Biotechnology - An open letter to graduate students and other procrastinators: it’s time to write
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 21/03/2025
Please can someone explain the logic behind this? Cut back funding on your own researchers with an excuse saying that higher education should be de-internationalised and etc., but now directing the money to hire new internationals? 4/3 (now finished
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 21/03/2025
Now, the Dutch government announced a new funding program to hire foreign researchers!?! Isn't this a sleazy attempt to get a piece of cake from the oncoming American researcher overflow? Why did you cut the funding for the already working foreigner researchers? 3/3 (one more)
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 21/03/2025
So they told universities to cut back on their expenses. But like a lot! Then, naturally, some Dutch universities fired their employees, i.e. researchers (looking at you Twente). Lots of departments are trying to find ways to scale down because the budgets are hundreds of millions less now. 2/3
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 21/03/2025
Please someone correct me if I got this wrong: the recent Dutch government made it clear that they don't want foreign students anymore and said that the money being spent on them was too much. They also decided that money being spent on research was too much in general. 1/3
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Giulia Lavarda @giulialavarda.bsky.social · 18/02/2025
💡 Looking for #FacultyPositions in Europe? The search can be a maze! I shared my personal journey in this @cp-matter.bsky.social article, thanks to an invite from @cranfordmatter.bsky.social. 🔓 Free access here 👉 authors.elsevier.com/c/1kZ4b9Cyxd... #chemsky #AcademicLife #CareersInScience
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 08/02/2025
I'm sure everyone has been telling you this but let me do it as well: getting a PhD is an emotional rollercoaster. You live by those small glimpses of successful experiments in between a ton of failures. Everyday is a new journey and you try to keep it stable.
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PHD Comics @phdcomics.com · 07/01/2025
Watch out for those bastard professors
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Science Magazine @science.org · 26/12/2024
By mapping the meanings of the words used to communicate emotions across more than one-third of the planet’s spoken languages, a study in Science found that there is significant variation in how emotions are expressed across cultures. #ScienceMagArchives scim.ag/41X6dDk
scim.ag
Emotion semantics show both cultural variation and universal structure
Analysis of the terms used for emotions across a sample of 2474 spoken languages reveals low similarity across cultures.
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Rosa Ritunnano @rritunnano.bsky.social · 20/12/2024
Instead of listing my publications, as the year draws to an end, I want to shine the spotlight on the commonplace assumption that productivity must always increase. Good research is disruptive and thinking time is central to high quality scholarship and necessary for disruptive research.
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Dr Connor Wells @connorwells95.bsky.social · 21/11/2024
I had the great pleasure of coordinating our annual "35 challenges in materials science". Was super fun to organise and engage with all these brilliant scientists! Take a look at what this year's cohort of materials scientists are working on! #Matter www.cell.com/matter/abstr...
cell.com
35 challenges in materials science being tackled by PIs under 35(ish) in 2024
Here, we highlight 35 global researchers approximately under the age of 35. This third annual cohort was self-generated by initial seed invitations sent by the editorial team, with each contributor su...
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 17/12/2024
Even after you finish you keep thinking "I could've done this and that"...
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Claus Wilke @clauswilke.com · 17/12/2024
Bioart, courtesy of the NIH. All images are in the public domain and available for download as high-quality SVGs. bioart.niaid.nih.gov
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samuel mehr @mehr.nz · 05/12/2024
What's your favourite example of a basic science discovery yielding practical results later on — but that one didn't know it would be used for at the time?
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Berna Devezer @devezer.bsky.social · 15/09/2023
🧵 I'll talk up a recent paper I loved working on. We show why meaningful replications need to be based on deeper theoretical understanding & stronger empirical foundations. It's a theory paper like our other metascientific work. 🧪 #metasci #philsci #stats royalsocietypublishing.org/doi/full/10....
Screenshot of the article that says:

Royal Society Open Science
The logical structure of experiments lays the foundation for a theory of reproducibility
Erkan O. Buzbas, Berna Devezer and Bert Baumgaertner
Published:15 March 2023Abstract
The scientific reform movement has proposed openness as a potential remedy to the putative reproducibility or replication crisis. However, the conceptual relationship among openness, replication experiments and results reproducibility has been obscure. We analyse the logical structure of experiments, define the mathematical notion of idealized experiment and use this notion to advance a theory of reproducibility. Idealized experiments clearly delineate the concepts of replication and results reproducibility, and capture key differences with precision, allowing us to study the relationship among them. We show how results reproducibility varies as a function of the elements of an idealized experiment, the true data-generating mechanism, and the closeness of the replication experiment to an original experiment. We clarify how openness of experiments is related to designing informative replication experiments and to obtaining reproducible results. With formal backing and ...
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Derek Lowe @dereklowe.bsky.social · 02/12/2024
Fluorescently labeled proteins are essential to research. But we should never forget how messed-up their behavior can be. An example from condensates:
science.org
Fluorescent Tags Are Basically Never Silent
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Nikolai Slavov @slavov-n.bsky.social · 01/12/2024
Timescales in Cell Biology
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Kerstin Göpfrich @kgoepfrich.bsky.social · 15/07/2024
Last year we met with about 60 scientists for 2 weeks to discuss what it means to synthesize life. Here is the summary of our discussion: chemrxiv.org/engage/chemrxiv/articl… We hope it represents diverse views and serves as a roadmap towards...
chemrxiv.org
A roadmap towards the synthesis of Life
The synthesis of life from non-living matter has captivat...
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Yiğitcan Sümbelli @ysumbelli.bsky.social · 18/11/2024
Hello world! I'm here, too!
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