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Reposted by Yogesh Hooda

Child Health Research Foundation @chrfbd.bsky.social · 04/03/2026

1/ We are thrilled to share that CHRF has been awarded a Wellcome Discovery Award to study severe RSV pneumonia in children. Read more in our press release: chrfbd.org/blogs/2c839d...

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Reposted by Yogesh Hooda

Child Health Research Foundation @chrfbd.bsky.social · 16/07/2025

1/ In April 2024, a routine lab isolate of Salmonella Typhi showed phenotypic resistance to ceftriaxone, a key antibiotic for treating typhoid. By September, 47 similar cases had been identified across Bangladesh, and resistance had risen to 5%.

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Reposted by Yogesh Hooda

senjutisaha.bsky.social @senjutisaha.bsky.social · 23/06/2025

One ceftriaxone-resistant #typhoid case last year set us on a path that is now live on Emerging Infectious Diseases. 47 cases in months, resistance rose from 0 to 5%. We spoke with patients, sequenced samples. 4.3.1.2.B1 lineage+blaCTX-M-15 on pCROB1. #AMR #PublicHealth wwwnc.cdc.gov/eid/article/...

wwwnc.cdc.gov

Outbreak of Ceftriaxone-Resistant <em>Salmonella enterica</em> Serovar Typhi, Bangladesh, 2024

Ceftriaxone-Resistant <em>Salmonella</em> Typhi, Bangladesh

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Reposted by Yogesh Hooda

Willem van Schaik @wvschaik.bsky.social · 24/10/2024

This is amazing and important work by Glen Carter and colleagues at the University of Melbourne 'Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin in Enterococcus' www.nature.com/articles/s41...

nature.com

Rifaximin prophylaxis causes resistance to the last-resort antibiotic daptomycin - Nature

Rifaximin use, particularly in patients with liver cirrhosis, may be compromising the clinical use of daptomycin.

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Yogesh Hooda @yogihooda.bsky.social · 25/12/2024

When people ask me what we need the most for typhoid treatment, I always say a rapid diagnostic to accurately detect typhoid/paratyphoid. This truly could be a game changer if we can adopt it in clinical practice in LMICs. Great work from colleagues at @chrfbd.bsky.social and collaborators!!

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Yogesh Hooda @yogihooda.bsky.social · 05/12/2024

Had the amazing opportunity to present our work at HCA Asia. RSV infections are a major health burden amongst children in Bangladesh and we aim to learn about the pathophysiology of RSV infections using single cell sequencing. Stay tuned for more insights from our work!

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Reposted by Yogesh Hooda

senjutisaha.bsky.social @senjutisaha.bsky.social · 04/12/2024

My heart swells with pride every time I realise that Bangladesh is generating its own single cell data @chrfbd.bsky.social !! Excellent presentation by @yogihooda.bsky.social at the #HCAAsia2024 meeting describing the changes in the nasal mucosa during #RSV infections!

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Reposted by Yogesh Hooda

MRC Laboratory of Molecular Biology @mrclmb.ac.uk · 29/11/2024

Huping Wang and Manu Hegde, in @cellbiol-mrclmb.bsky.social have found a factor that accelerates protein deliveries to the endoplasmic reticulum Click here to read more about it: www2.mrc-lmb.cam.ac.uk/discovery-of... #LMBResearch

Model depicting the early steps during production of a membrane protein

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Reposted by Yogesh Hooda

senjutisaha.bsky.social @senjutisaha.bsky.social · 30/11/2024

Aging together, striving to become better scientists together, getting through this world together. 14 years with @yogihooda.bsky.social since our first date night - crazy!!!

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Reposted by Yogesh Hooda

Child Health Research Foundation @chrfbd.bsky.social · 28/11/2024

Dr. Senjuti Saha recently took the stage at Cambridge University to share insights on the growing crisis of neonatal infections and antimicrobial resistance (AMR) in Bangladesh. She discussed how CHRF’s invasive bacterial disease surveillance is revealing crucial data on Klebsiella pneumoniae. (1/4)

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Yogesh Hooda @yogihooda.bsky.social · 22/11/2024

Excited to share our preprint on characterizing NACHO, a ER-resident membrane protein that plays an essential role in assembling pentameric ion channels, like GABA and nicotinic acetylcholine receptors in our brains. #IonChannels #Neuroscience (1/5) www.biorxiv.org/content/10.1...

biorxiv.org

Mechanism of NACHO-mediated assembly of pentameric ligand-gated ion channels

Pentameric ligand-gated ion channels (pLGICs) are cell surface receptors of crucial importance for animal physiology[1][1]–[4][2]. This diverse protein family mediates the ionotropic signals triggered...

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Yogesh Hooda @yogihooda.bsky.social · 22/11/2024

Recently, I got an opportunity to present 18 years of impactful research from CHRF in Bangladesh at the 2024 Klebsiella Epidemiology and Biology Symposium in Paris—the first-ever event dedicated to this infection. (1/3)

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