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Yu Nagat

@ynagata.bsky.social

5 followers 9 following 0 posts

Ph.D student in @kazu-maeshima.bsky.social, @nigidenken.bsky.social in Japan.

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Reposted by Yu Nagat

Kazuhiro Maeshima @kazu-maeshima.bsky.social · 26/09/2026

🧬 Highly related @natgenet.nature.com paper from @binzmit.bsky.social group, using nucleosome-resolution chromatin modeling: Euchromatin forms condensed domains with short active regions on the surface www.nature.com/articles/s41... Congratulations! 🎉

nature.com

Euchromatin forms condensed domains with short active regions on the surface - Nature Genetics

Simulations integrating micro-C and imaging data provide a coherent view of chromatin organization from nucleosomes to clutches to domains, revealing that most regions form compact domains but short r...

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Reposted by Yu Nagat

Kazuhiro Maeshima @kazu-maeshima.bsky.social · 18/09/2026

🧬 Our “Behind the Paper” is now online at Nature Communities: “Active chromatin is not simply open—it forms compact domains that cohesin keeps from mixing.” 📖 A short story behind our recent @natgenet.nature.com paper. communities.springernature.com/posts/active... www.nature.com/articles/s41...

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Reposted by Yu Nagat

Kazuhiro Maeshima @kazu-maeshima.bsky.social · 08/09/2026

Is euchromatin really “open”? 🧬 Using super-resolution imaging🔬 our new study @natgenet.nature.com reveals: Euchromatin forms condensed domains in live cells. Cohesin constrains them and prevents domain mixing for proper transcriptional insulation🚧 🔗 www.nature.com/articles/s41... (1/2)

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Reposted by Yu Nagat

Kazuhiro Maeshima @kazu-maeshima.bsky.social · 07/07/2026

Our new preprint @biorxivpreprint.bsky.social, led by @katsuminami.bsky.social‬ et al.! 🎉 www.biorxiv.org/content/10.6... Machine learning-assisted Repli-Histo labeling and single-nucleosome imaging reveal distinct transcription-dependent chromatin constraints across euchromatin and heterochromatin.

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