Implicit solvent models (ISMs) promise to deliver the accuracy of explicit solvent simulations at a fraction of the computational cost. However, despite decades of development, their accuracy has rema...

Chromatin structure and dynamics are central to nearly every aspect of eukaryotic gene regulation. The spatial organization of the genome influences how genes a

DNA's physical properties play a central role in genome organization and regulation, but simulating its behavior across biologically relevant scales remains a major computational challenge. Coarse gra...