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Xosé M Fernández

@xosegb.bsky.social
211 followers 461 following 496 posts

Genomicist with many hats: data & innovation - molecular medicine, translational research and science • Opinions expressed here are my own • RT ≠ endorsement

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Xosé M Fernández @xosegb.bsky.social · 02/10/2026
Cancer du sein : un traitement au long cours, un défi psychologique persistant www.polytechnique-insights.com/tribunes/san...
polytechnique-insights.com
Cancer du sein : un traitement au long cours, un défi psychologique persistant
Cancer du sein : un traitement au long cours, un défi psychologique persistant - Une Tribune à découvrir sur Polytechnique Insights
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Xosé M Fernández @xosegb.bsky.social · 20/09/2026
On evidence in medicine @philipcball.bsky.social www.thenewworld.co.uk/philip-ball-...
app.thenewworld.co.uk
What if we’ve got ultra-processed foods wrong?
Fresh analysis of dietary trials raises some awkward questions about UPFs and evidence-based science
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Xosé M Fernández @xosegb.bsky.social · 20/09/2026
Claude Definitely Didn't Solve Protein Design. That's Kind of the Point #LLM joehorsman.substack.com/p/claude-def...
joehorsman.substack.com
Claude Definitely Didn't Solve Protein Design. That's Kind of the Point.
If you just read the headlines, apparently Claude can design proteins now.
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Xosé M Fernández @xosegb.bsky.social · 20/09/2026
An Essay on Bioinformatics higginsinformatics.substack.com/p/an-essay-o...
higginsinformatics.substack.com
Kyle Higgins | Substack
Sick of AI-generated bioinformatics slop? Boring! Subscribe for human-generated bioinformatics slop. Click to read Kyle Higgins on Substack. Launched 3 days ago.
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Xosé M Fernández @xosegb.bsky.social · 18/09/2026
Genomics addressed its ethical concerns, #AI can do the same www.ft.com/content/6640...
ft.com
Genomics addressed its ethical concerns, AI can do the same
When science is moving faster than legislation, we must stay humble
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Xosé M Fernández @xosegb.bsky.social · 27/08/2026
Rethinking global cancer guidelines bmjoncology.bmj.com/content/5/2/...
bmjoncology.bmj.com
Rethinking global cancer guidelines
Around the world, cancer is being treated according to guidelines often developed without a formative, inclusive local process. The clinical practice guidelines (CPGs) are ‘systematically developed st...
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Reposted by Xosé M Fernández
Matthew Cobb @matthewcobb.bsky.social · 30/07/2026
Here I am chatting with Angela Saini for the Science podcast.
science.org
Crick: A Mind in Motion
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Xosé M Fernández @xosegb.bsky.social · 09/07/2026
Human-Pig Interactions in Liver Xenotransplant Recipients: A Multi-Omics Study www.insideprecisionmedicine.com/topics/trans...
insideprecisionmedicine.com
Human-Pig Interactions in Liver Xenotransplant Recipients: A Multi-Omics Study
The results suggest that genetic engineering and targeted therapeutics may improve porcine liver xenograft compatibility to optimize xenotransplantation.
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Xosé M Fernández @xosegb.bsky.social · 08/07/2026
The demise of Moore’s law economist.com/science-and-...
economist.com
The future of chipmaking looks more like Manhattan than Silicon Valley
Constrained by physics and politics, chipmakers are building upwards
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Xosé M Fernández @xosegb.bsky.social · 06/07/2026
Cancer screening expands as implementation gaps remain www.thelancet.com/journals/lan...
clinicalkey.com
ClinicalKey
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Xosé M Fernández @xosegb.bsky.social · 03/07/2026
L’Europe décroche, peut-elle accélérer en matière d’innovation ? www.polytechnique-insights.com/tribunes/eco...
polytechnique-insights.com
L’Europe décroche, peut-elle accélérer en matière d’innovation ?
L’Europe décroche, peut-elle accélérer en matière d’innovation ? - Une Tribune à découvrir sur Polytechnique Insights
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Xosé M Fernández @xosegb.bsky.social · 29/06/2026
LLM-Assisted Reanalysis of Unsolved Rare Disease Genomes Increases Diagnostic Yield ai.nejm.org/doi/full/10....
ai.nejm.org
LLM-Assisted Reanalysis of Unsolved Rare Disease Genomes Increases Diagnostic Yield
Rare and undiagnosed genetic disorders affect millions of patients globally, and many patients endure years of inconclusive testing. Conventional genomic interpretation can be insufficiently sensit...
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Xosé M Fernández @xosegb.bsky.social · 23/06/2026
Rewiring the life sciences: why foundations come first for #AI in science news.cancerresearchuk.org/2026/06/22/r...
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Xosé M Fernández @xosegb.bsky.social · 22/06/2026
. @ukbiobank.ac.uk case reveals the need for mandatory accreditation of trusted research environments www.bmj.com/content/393/...
bmj.com
UK Biobank case reveals the need for mandatory accreditation of trusted research environments
When UK Biobank deidentified data appeared on an online Chinese marketplace, it prompted concern about data security.1 UK Biobank withdrew researcher access to their platform and within weeks publishe...
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Xosé M Fernández @xosegb.bsky.social · 20/06/2026
Who owns my health data? www.nature.com/articles/s41...
nature.com
Who owns my health data? - Nature Medicine
The geopolitics driving artificial intelligence superpowers is reshaping biomedical datasets, and who has access to them.
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Xosé M Fernández @xosegb.bsky.social · 19/06/2026
Why the Human Genome’s Tangled Physicality May Confound #AI www.quantamagazine.org/why-the-huma...
quantamagazine.org
Why the Human Genome’s Tangled Physicality May Confound AI | Quanta Magazine
Our genetic heritage is not a blueprint or an algorithm, as many biologists have imagined, but something else entirely.
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Xosé M Fernández @xosegb.bsky.social · 17/06/2026
Why #AI cannot do good science without humans www.nature.com/articles/d41...
nature.com
Why AI cannot do good science without humans
With the arrival of ‘AI scientists’, it’s as well to remember that human wisdom, empathy and sheer messiness are as much part of progress as are process and efficiency.
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Xosé M Fernández @xosegb.bsky.social · 17/06/2026
A must read for those working in #AI in #healthcare - Why almost all #ML models for #medicine are wrong-and what we need for evidence-based medical AI www.sciencedirect.com/science/arti...
sciencedirect.com
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Xosé M Fernández @xosegb.bsky.social · 12/06/2026
Hetairos Classifies 102 CNS #Tumour Subtypes in Minutes #AI www.insideprecisionmedicine.com/topics/oncol...
insideprecisionmedicine.com
AI Tool Classifies 102 CNS Tumor Subtypes in Minutes
Hetairos can classify 102 molecular tumor subtypes of CNS cancers using digitized H&E slides, delivering diagnostic findings in minutes.
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Xosé M Fernández @xosegb.bsky.social · 09/06/2026
Is Britain's health establishment prepared for a populist government? www.bmj.com/content/393/...
bmj.com
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Xosé M Fernández @xosegb.bsky.social · 08/06/2026
Universal #Coronavirus #Vaccine Could Provide Protection Against Future Strains www.insideprecisionmedicine.com/topics/coron...
insideprecisionmedicine.com
Universal Coronavirus Vaccine Could Provide Protection Against Future Strains
The first human trial of a universal coronavirus vaccine shows early promise for vaccines against a broad range of viral strains.
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Xosé M Fernández @xosegb.bsky.social · 08/06/2026
Europe Isn't Behind, Says Arthur Mensch, Mistral www.bfmtv.com/economie/ent...
bfmtv.com
"Ce récit est assez faux": Arthur Mensch (Mistral AI) estime que l'Europe n'est pas en retard face aux États-Unis en matière d'intelligence artificielle
Dans un entretien à La Tribune Dimanche, le fondateur et PDG de l’entreprise qui veut rendre " l’IA de pointe accessible à tous" rappelle les nombreux atouts du Vieux continent en général et de la Fra...
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Xosé M Fernández @xosegb.bsky.social · 04/06/2026
ASCO Won't Recommend Galleri as NHS Trial Data Reignites Debate Over MCED Evidence Standards www.genomeweb.com/cancer/asco-...
genomeweb.com
ASCO Won't Recommend Galleri as NHS Trial Data Reignites Debate Over MCED Evidence Standards
The trial missed its primary endpoint but showed the test can detect cancers earlier, fueling questions around the best framework to evaluate MCED tests.
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Xosé M Fernández @xosegb.bsky.social · 22/05/2026
Comment chasser les erreurs dans les publications médicales www.polytechnique-insights.com/tribunes/soc...
polytechnique-insights.com
Recherche : comment chasser les erreurs dans les publications médicales
Recherche : comment chasser les erreurs dans les publications médicales - Une Tribune à découvrir sur Polytechnique Insights
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Xosé M Fernández @xosegb.bsky.social · 19/05/2026
UK government plans to increase the price the #NHS pays for drugs faces legal challenge over changes to #NICE www.bmj.com/content/393/...
bmj.com
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Reposted by Xosé M Fernández
Martin McKee @martinmckee.bsky.social · 16/05/2026
We were lucky (so far) with the Hantavirus outbreak. Next time we may not be. @who.int @ecdc.europa.eu and teams in South Africa & elsewhere responded very well, but 🇺🇸 is missing in action. My article in @prospectmagazine.co.uk www.prospectmagazine.co.uk/politics/pol...
prospectmagazine.co.uk
We were lucky with Hantavirus—next time we might not be
The outbreak aboard a Dutch cruise ship offers vital lessons for the inevitable next pandemic
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Xosé M Fernández @xosegb.bsky.social · 13/05/2026
Hantavirus outbreak on the MV Hondius cruise: from the emergency response to unresolved lessons gacetamedica.com/opinion/trib...
gacetamedica.com
Brote de hantavirus en el crucero MV Hondius: del operativo de emergencia a las lecciones pendientes
El despliegue sanitario empieza a ordenar la situación, pero las semanas decisivas serán las de la vigilancia, la comunicación y el aprendizaje institucional.
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Xosé M Fernández @xosegb.bsky.social · 11/05/2026
Fabricated citations: an audit across 2·5 million biomedical papers #LLM #hallucinations www.thelancet.com/journals/lan...
thelancet.com
Fabricated citations: an audit across 2·5 million biomedical papers
Scientific literature depends on the integrity of its references. Each reference implicitly asserts that a verifiable source exists and supports the claims being made. When references point to non-exi...
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Xosé M Fernández @xosegb.bsky.social · 10/05/2026
Peptideins - Expanding the human proteome www.nature.com/articles/s41...
nature.com
Expanding the human proteome with microproteins and peptideins - Nature
A large-scale proteomics analysis of the dark proteome by the TransCODE Consortium reveals many translated non-canonical open reading frames to encode microproteins and peptideins.
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Xosé M Fernández @xosegb.bsky.social · 09/05/2026
Craig Venter raced to decode the human genome economist.com/obituary/202...
economist.com
Craig Venter raced to decode the human genome
The dark horse of the Human Genome Project died on April 29th, aged 79
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Reposted by Xosé M Fernández
Calume @calume.bsky.social · 06/05/2026
Ente les visites guapes y prestoses na Llibrería Trabe con motivu de la publicación de 'El motor de la historia' de Rafael Rodríguez Valdés, ye obligao destacar la del profesor @xulioviejo.bsky.social gran filólogu, amás d'amigu d'esta casa. Como se diz nel prólogu del llibru, Xulio ye un referente.
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Xosé M Fernández @xosegb.bsky.social · 07/05/2026
MedTech : pourquoi le passage à l’échelle passe-t-il par les États-Unis ? www.polytechnique-insights.com/tribunes/san...
polytechnique-insights.com
MedTech : pourquoi le passage à l'échelle passe-t-il par les États-Unis ?
MedTech : pourquoi le passage à l'échelle passe-t-il par les États-Unis ? - Une Tribune à découvrir sur Polytechnique Insights
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Xosé M Fernández @xosegb.bsky.social · 07/05/2026
AI supposedly outperforms doctors in US study, but experts urge caution www.bmj.com/content/393/...
bmj.com
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Xosé M Fernández @xosegb.bsky.social · 05/05/2026
Who owns my health data? www.nature.com/articles/s41...
nature.com
Who owns my health data? - Nature Medicine
The geopolitics driving artificial intelligence superpowers is reshaping biomedical datasets, and who has access to them.
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Reposted by Xosé M Fernández
Philip Ball @philipcball.bsky.social · 04/05/2026
This is a great and balanced discussion of Craig Venter and what he achieved, featuring @rogerhighfield.bsky.social @rowhoop.bsky.social @michaelmarshall.newsmast.social.ap.brid.gy and @pennysarchet.bsky.social www.youtube.com/watch?v=1Jin...
youtube.com
The Rich and Complicated Legacy of Craig Venter
YouTube video by The World, The Universe And Us
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Xosé M Fernández @xosegb.bsky.social · 04/05/2026
Under a third of British patients get diagnosis within 28 days at some hospitals www.bmj.com/content/393/...
bmj.com
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Xosé M Fernández @xosegb.bsky.social · 01/05/2026
A Treasure Trove of Cambrian Fossils Rewrites the Story of Early Life www.quantamagazine.org/a-treasure-t...
quantamagazine.org
A Treasure Trove of Cambrian Fossils Rewrites the Story of Early Life | Quanta Magazine
Remarkably preserved fossils found in southern China offer a fascinating window into what life looked like at the end of the Cambrian explosion, with half of the species uncovered being new to science...
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Xosé M Fernández @xosegb.bsky.social · 11/04/2026
Anthropic closes in on OpenAI as US business use surges www.ft.com/content/abb9...
ft.com
Anthropic closes in on OpenAI as US business use surges
Divergence reflects company’s recent rapid growth owing to strong interest in its Claude Code products
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Xosé M Fernández @xosegb.bsky.social · 22/02/2026
More than one-third of #cancer cases are preventable www.nature.com/articles/s41...
nature.com
Global and regional cancer burden attributable to modifiable risk factors to inform prevention - Nature Medicine
Global cancer estimates across 185 countries show that 7.1 million new cancer cases were attributable to modifiable risk factors in 2022, with smoking, infections and alcohol consumption being the lea...
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Reposted by Xosé M Fernández
Paul J Davies @pauljdavies.bsky.social · 20/02/2026
Fascinating piece by @jburnmurdoch.ft.com - UK graduate earnings premium is shrinking because the economy is bad and there aren’t enough high paying jobs >> www.ft.com/content/649d... ‘Is university still worth it?’ is the wrong question
In the UK, the graduate earnings premium shrank as the share of grads in the workforce rose. In the US, Netherlands, Spain, France, Canada the premium kept rising.
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Reposted by Xosé M Fernández
Scientific American @sciam.bsky.social · 18/02/2026
After initially rejecting Moderna’s application for review, the FDA will now consider the mRNA flu shot
scientificamerican.com
FDA agrees to review Moderna mRNA flu vaccine in dramatic reversal
After initially rejecting Moderna’s application for review, the FDA will now consider the mRNA flu shot
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Xosé M Fernández @xosegb.bsky.social · 18/02/2026
With clinical trials leaving the US, could Europe benefit? www.bmj.com/content/392/...
bmj.com
Why clinical trials are leaving the US—and Asia and Australia are welcoming them
Disruption and uncertainty in the US are leading many clinical trials to consider other countries for participation. Jennifer Lutz , Neha Bhatt , and Flynn Murphy report on the changing landscape—and ...
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Reposted by Xosé M Fernández
EMBL-EBI @ebi.embl.org · 17/02/2026
The AlphaFold Database, jointly developed with Google DeepMind, now contains datasets from specialist communities. This includes rich datasets for microbes, viruses & parasites associated with tropical diseases. Explore the new datasets in the AlphaFold Database. www.ebi.ac.uk/about/news/u...
ebi.ac.uk
AlphaFold Database welcomes community datasets
Latest AlphaFold Database update adds high-value datasets for microbial and viral proteins, generated by specialist communities
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Reposted by Xosé M Fernández
EMBL-EBI @ebi.embl.org · 18/02/2026
Mentoring doesn’t just shape careers, it shapes people’s lives. Our Director Emeritus Janet Thornton shares with @natmethods.nature.com what mentoring has meant during her career. 💬 What’s the most valuable mentoring advice you’ve received or shared? www.nature.com/articles/s41...
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Reposted by Xosé M Fernández
The Royal Society @royalsociety.org · 20/02/2025
With this week's Royal Society #TransformingOurFuture conference on Quantum Information, we're happy to be helping to kick off the UN International Year of Quantum in the UK with @instituteofphysics.bsky.social. Catch the livestream here: royalsociety.org/science-even...
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Xosé M Fernández @xosegb.bsky.social · 18/02/2026
Interesting analysis of #EHDS impact to non-EU members ai.nejm.org/doi/full/10....
ai.nejm.org
Driving AI Health Innovation through the European Health Data Space: Opportunities and Challenges for Non-EU Country Participation
In March 2025, the European Union (EU) launched the European Health Data Space (EHDS) to streamline access to and sharing and reuse of health data across all 27 Member States. The EHDS aims to give...
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Xosé M Fernández @xosegb.bsky.social · 14/02/2026
What’s the point of #AI in acupuncture? #TCM economist.com/china/2026/0...
economist.com
What’s the point of AI in acupuncture?
Traditional Chinese medicine meets modernity
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Xosé M Fernández @xosegb.bsky.social · 13/02/2026
The regulatory environment in the United States is changing so vaccine makers face increasingly uncertainty #Moderna #mRNA www.fiercepharma.com/pharma/fdas-...
fiercepharma.com
With the FDA's Moderna decision, vaccine makers face increasingly uncertain regulatory environment
The regulatory environment in the United States encountered by Moderna during the development of its COVID-19 vaccine bears little resemblance to what the company experienced earlier this week when | ...
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Xosé M Fernández @xosegb.bsky.social · 13/02/2026
Reams of cells’ #genetic data in the latest neurobiological cartography effort #ML www.quantamagazine.org/fed-on-reams...
quantamagazine.org
Fed on Reams of Cell Data, AI Maps New Neighborhoods in the Brain | Quanta Magazine
Machine learning is helping neuroscientists organize vast quantities of cells’ genetic data in the latest neurobiological cartography effort.
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Xosé M Fernández @xosegb.bsky.social · 07/02/2026
Les odeurs que nous aiming www.epsiloon.com/compte/reade...
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