iiinova — where your digital self keeps evolving

Will Lawn @willlawn.bsky.social · 06/08/2026

Pls can @lewisham.gov.uk repave and then weed our Littlewood st pavement (SE13) so pedestrians, prams and wheelchairs can safely use it. I was told the weeds would be removed by 31 July - they aren't. Why is ours so much worse than others nearby? @liamshrivastava.bsky.social @janetdaby.bsky.social

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Will Lawn @willlawn.bsky.social · 20/05/2026

Want to participate in a randomised cannabinoid administration experiment at King's College London? We are studying the effects of THC and CBD on physiological stress, following poor sleep. You will be paid £92 for your time. Please complete this form qualtrics.kcl.ac.uk/jfe/form/SV_...

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Will Lawn @willlawn.bsky.social · 01/05/2026

We provide an overview of transcranial ultrasound stimulation (TUS) in the context of Substance Use Disorders here, including possible targets and mechanisms, and ongoing international research. doi.org/10.1007/s404...

doi.org

Transcranial Ultrasound Stimulation as an Emerging Treatment for Substance use Disorder: Promise and Precaution - Current Addiction Reports

Current Addiction Reports -

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Will Lawn @willlawn.bsky.social · 01/05/2026

Could the presence of CBD in cannabis actually increase the levels of circulating plasma THC and THC-metabolites after inhalation? That's what we report in Drug and Alcohol Dependence. Thanks to Dr Dan Hall for leading this. www.sciencedirect.com/science/arti...

sciencedirect.com

Plasma cannabinoid pharmacokinetics following the inhalation of vaporised cannabis with and without cannabidiol

The presence of cannabidiol (CBD) in cannabis may alter cannabinoid pharmacokinetics, however previous research has produced mixed results. Furthermor…

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Will Lawn @willlawn.bsky.social · 27/02/2026

First longitudinal MRI paper from our CannTeen study (n=96) shows that over 1-yr #cannabis use is associated with reductions in activity in the ventral striatum when anticipating money #reward. Congrats to Dr Martine Skumlien lead author and the whole CannTeam. www.nature.com/articles/s41...

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Will Lawn @willlawn.bsky.social · 17/02/2026

New paper led by Cassie Bloy - analysis of our KARE trial data. Studied acute psychoactive effects of IV ketamine in AUD over 3 infusions and if they explained clinical benefit. Strong altered states, but subjective effects did not mediate reduced drinking. onlinelibrary.wiley.com/doi/10.1111/...

onlinelibrary.wiley.com

The psychoactive effects of repeated ketamine infusions and their mechanistic role in the treatment of alcohol use disorder: Secondary analysis of a randomised controlled trial

Background and aims Ketamine assisted psychotherapy is a promising new treatment for alcohol use disorder (AUD). The psychoactive effects of repeated intravenous (IV) ketamine infusions in people wi...

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Will Lawn @willlawn.bsky.social · 05/01/2026

Please do this 5-minute survey which asks how you feel about people who use cannabis: qualtrics.kcl.ac.uk/jfe/form/SV_... One of my excellent undergraduate research project students has designed the study, and needs more participants. Thanks!! Fully anonymous. No payment.

qualtrics.kcl.ac.uk

Qualtrics Survey | Qualtrics Experience Management

The most powerful, simple and trusted way to gather experience data. Start your journey to experience management and try a free account today.

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Will Lawn @willlawn.bsky.social · 02/07/2025

We have published our new review 'Recent Innovations to Detect and Intervene to Prevent Opioid Overdose Deaths' led by Basak Tas and John Strang. kclpure.kcl.ac.uk/portal/en/pu...

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Will Lawn @willlawn.bsky.social · 01/07/2025

See our 4-year longitudinal CannTeen findings in our pre-print here: osf.io/8hmy9/ Joint first authors: Ayse Doga Lamper and Layla Sadek.

osf.io

Four-year trajectories of mental health symptoms in adolescents and adults who do and do not use cannabis

Hosted on the Open Science Framework

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Will Lawn @willlawn.bsky.social · 30/06/2025

Pleased to say that I've been awarded a small Impact Acceleration grant to scale up my cannabis education school assemblies and explore their acceptability and short-term impact on early-mid adolescents.

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Will Lawn @willlawn.bsky.social · 27/06/2025

We analysed data from the KARE trial (n=96) to examine ketamine’s (0.8mg/kg infusion) psychoactive effects in alcohol use disorder and whether they mediate treatment response. Drug effects were strong and mainly onsistent across 3 infusions, but did not mediate reduced drinking. osf.io/kbswd

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Will Lawn @willlawn.bsky.social · 11/06/2025

The London Drugs Commission report on cannabis makes several recommendations which I support. We must (1) deliver research-informed cannabis education to *early* adolescents, (2) offer evidence-based, specialist treatment for CUD to youth and adults. www.london.gov.uk/programmes-s...

london.gov.uk

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Will Lawn @willlawn.bsky.social · 24/04/2025

Enjoyed presenting at #SOBP2025 on a #cannabis symposium organised by @emesekroon.bsky.social & @jcousijn.bsky.social. I presented 4-year longitudinal CannTeen data: teens who quit cannabis have reduced psychotic-like symptoms, and over 4 yrs teens are > sensitive to impact of frequent C use on CUD.

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Dr Lucy Foulkes @lucyfoulkes.bsky.social · 26/02/2025

I've been asked why negative effects might happen in universal school MH interventions, so going to share thoughts here. Short answer is we don't know, but there are multiple (not mutually exclusive) possibilities: (thread)

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Will Lawn @willlawn.bsky.social · 25/02/2025

We need to better understand ketamine use in YP. And we need to improve prevention of and treatment for problem ketamine use. But when you read stories like this www.bbc.co.uk/news/article... you would think all YP are doing k. SDD in YP shows 0.4% 14-yos & 2.5% of 15-yos have used k in past yr.

bbc.co.uk

Generation K: The disturbing rise of ketamine abuse among young people

Increasing numbers of young people are using the drug, experts say. The health impacts can be catastrophic.

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Will Lawn @willlawn.bsky.social · 15/02/2025

Credit to Dr Basak Tas and Sir John Strang for this important and challenging work which I had the privilege of being involved with. This study demonstrates the feasibility of the lab model of OD. More work needed to really explore impact of dose on respiratory depression @kingsioppn.bsky.social

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Alex Stevens @profalexstevens.bsky.social · 13/02/2025

The long-awaited evaluation of Project ADDER is now out, and makes fascinating reading for all with a concern for illicit drug problems in England and Wales. A thread: 1/? ttps://www.gov.uk/government/publications/project-adder-impact-evaluation/project-adder-impact-evaluation#key-findings

gov.uk

Project ADDER: Impact evaluation

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Will Lawn @willlawn.bsky.social · 11/02/2025

Dr Basak Tas has published her important experimental work investigating the respiratory depressant effects of diamorphine in people with OUD. She increased dose of drug by 10 & 20% and measured respiratory function, in n=4. Honoured to be a part of this work. onlinelibrary.wiley.com/doi/10.1111/...

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Will Lawn @willlawn.bsky.social · 11/02/2025

🚨New Paper- How does the brain value #cannabis vs. snacks? 🍃🍔 Using fMRI & real purchases, we found strong cannabis value signals in reward regions (vmPFC, ventral striatum, dpCC), but not for snacks. Thanks to PI & lead author @gillbedi.bsky.social 🔗 Read more: link.springer.com/article/10.1...

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Will Lawn @willlawn.bsky.social · 10/02/2025

Gray et al. (2025) report a well-powered (n=192) clinical trial testing 12 weeks of daily n-acetylcysteine for youth CUD. Prelim research suggested NAC might help youth stay abstinent when trying to quit. No significant difference NAC vs. placebo here. www.nature.com/articles/s41...

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Prof Ellie Dommett @profelliedommett.bsky.social · 23/01/2025

I am delighted to see @kingscollegelondon.bsky.social in the top 10 in the world for psychology. So much hard work goes into our work, and whilst rankings are not the be-all and end-all, it's a nice way to start 2025. www.timeshighereducation.com/world-univer...

timeshighereducation.com

World University Rankings by Subject 2025: Psychology

Top Psychology school rankings 2025: Leading universities for Psychological Studies Discover the Psychology Rankings results with the definitive Times Higher Education Subject Rankings 2025.

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Will Lawn @willlawn.bsky.social · 06/02/2025

Thanks to Catch22 and Tracy Scares for inviting me to speak at their Substance Misuse meeting about adolescent cannabis use. I've worked with Catch22, supporting them in their development of new PSHE cannabis education resources, which has been super rewarding.

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Institute of Psychiatry, Psychology & Neuroscience @kingsioppn.bsky.social · 22/01/2025

We’re at @wellcometrust.bsky.social for the launch of the Atlas of Longitudinal Datasets - a free online platform that maps longitudinal datasets around the world🌎 @larseneault.bsky.social @mqmentalhealth.bsky.social 🔗https://atlaslongitudinaldatasets.ac.uk/ #AtlasLongitudinalDatasets

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Richard Branson @richardbranson.bsky.social · 13/01/2025

Fantastic to see the UK’s first drug consumption room finally open its doors in Glasgow. Congratulations to all those who made this happen. As the experience from more than 200 drug consumption rooms around the world shows, The Thistle will save many lives: www.theguardian.com/society/2025...

theguardian.com

‘All eyes are on Glasgow’: UK’s first legal drug consumption room ready to open

The Thistle will be available 365 days a year and provide a supervised space where drugs can be injected safely

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Will Lawn @willlawn.bsky.social · 11/01/2025

It was a privilege to exhibit TheDifference's IncludEd25 event, advertising my assemblies and workshops about cannabis to educators from mainstream and alternative provision schools. Everyone's efforts to boost inclusion are inspiring. Great to make such meaningful connections.

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Will Lawn @willlawn.bsky.social · 10/01/2025

Great opinion piece from James Nicholls and Geoffrey Hunt. Dismissing the pleasures/benefits that people get from alcohol is naive, over-simplifies debates & ignores important motivations (-> reducing intervention efficacy). This doesn't prevent recognition of huge harms caused by alcohol.

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James Nicholls @jamesnicholls.bsky.social · 18/11/2024

New paper in @deppjournal.bsky.social looking at ethical and political divergences within drug policy reform advocacy through the lens of three key concepts in liberal thought: positive/negative freedom; rational autonomy and social contract www.tandfonline.com/doi/full/10....

tandfonline.com

Liberal moralities and drug policy reform

While debates on drug policy express a range of ethical viewpoints, many are underpinned by core ideas drawn from liberal philosophy. Much recent analysis on the moral principles underpinning drug ...

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Will Lawn @willlawn.bsky.social · 05/01/2025

New paper from the icps. People living in legal-cannabis US states and Canada are more likely to seek help for a cannabis problem using a health professional than people living in cannabis-illegal states in the US, who use alternative options www.sciencedirect.com/science/arti...

sciencedirect.com

Help-seeking behaviours among cannabis consumers in Canada and the United States: Findings from the international cannabis policy study

Little literature exists on what sources of help individuals utilize for cannabis-related problems. The current study examined the percentage of consu…

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Will Lawn @willlawn.bsky.social · 03/01/2025

The UK advisory council on misuse of drugs has published their SOP on how they say they evaluate harm and class of illegal recreational drugs. I'm sharing thanks to seeing Owen Bowden-Jones's tweet on X. assets.publishing.service.gov.uk/media/6777c924…

assets.publishing.service.gov.uk

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Will Lawn @willlawn.bsky.social · 29/12/2024

Osborne et al. analysed the #ABCD cohort to investigate the relationship between #cannabis use and #psychotic like symptoms in 10-15 year-olds. They found evidence for shared vulnerability and self-medication, & mixed evidence for cannabis contributing to harm (1/6) jamanetwork.com/journals/jam...

jamanetwork.com

Psychosis Spectrum Symptoms Before and After Adolescent Cannabis Use Initiation

This cohort study assesses associations between cannabis use and psychosis symptoms among adolescents.

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Will Lawn @willlawn.bsky.social · 29/12/2024

Doggett et al. report that, in the very early stages of Canadian cannabis legalisation, high-risk emerging adults show *less* of an 'age-ing out' trajectory (falling cannabis use while growing up) than similar ppl in Memphis USA (where cannabis is illegal). www.sciencedirect.com/science/arti...

sciencedirect.com

Evaluating the impact of Canadian cannabis legalization on cannabis use outcomes in emerging adults: Comparisons to a US control sample via a natural experiment

Recreational cannabis legalization marked a significant policy shift in Canada, but has been difficult to evaluate because of the absence of a control…

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Will Lawn @willlawn.bsky.social · 29/12/2024

Jayawardhana et al. report in JAMA Psychiatry that medical #cannabis laws are associated with an increase in #CUD and cannabis poisoning rate, and #recreational cannabis laws are associated with an increase in cannabis poisoning rate, using health insurance claim data 2011-2021 tinyurl.com/2p928nxw

tinyurl.com

Association of State Cannabis Legalization With Cannabis Use Disorder and Cannabis Poisoning

This longitudinal cohort study examines state-level medical and recreational cannabis laws’ association with cannabis use disorder and cannabis poisoning, overall and by sex and age subgroups, among U...

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Dom Oliver @domapoliver.bsky.social · 03/12/2024

Cannabis use is a known risk factor for psychosis but we've shown that cannabis withdrawal may also be associated with psychosis onset. Also, if these people keep using cannabis after psychosis onset, they have a much higher risk of relapse. doi.org/10.1192/bjp....

doi.org

Psychosis associated with cannabis withdrawal: systematic review and case series | The British Journal of Psychiatry | Cambridge Core

Psychosis associated with cannabis withdrawal: systematic review and case series

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Will Lawn @willlawn.bsky.social · 17/12/2024

Brilliant work by Marta Di Forti et al. In this single-arm, feasibility study they show that their cannabis clinic, for people with comorbid psychosis and cannabis use disorder, is feasible and is associated with reduced cannabis use and P symptoms & improved functional outcomes tinyurl.com/mstsrpxf

cambridge.org

A proof-of-concept analysis of data from the first NHS clinic for young adults with comorbid cannabis use and psychotic disorders | BJPsych Open | Cambridge Core

A proof-of-concept analysis of data from the first NHS clinic for young adults with comorbid cannabis use and psychotic disorders - Volume 11 Issue 1

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Will Lawn @willlawn.bsky.social · 14/12/2024

Amazing blog post from Matt about how to create these circle plots. I was lucky to see some sneak previews of our CannTeen data in this form, showing how vaporised thc and thc+cbd alter the 'persistence homological scaffold’ 🤷. To me, how modular different networks are. More to come from Matt soon!

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Prof Harry Sumnall @profhrs.bsky.social · 29/11/2024

New YP (under 18s) drug treatment data published. Cannabis and alcohol still by far the main drugs of concern, but ketamine presentations have increased by 2.6 % points since last year, and from 512 in 2021/2022 to 1201 in 2023/24 www.gov.uk/government/s...

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Will Lawn @willlawn.bsky.social · 27/11/2024

Will Donald Trump's favourite word stop the influx of fentanyl into the US!? Innovative international drug policy here we come

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Will Lawn @willlawn.bsky.social · 24/11/2024

WHO advocates for improved treatment of teenagers with #SUD, which I completely support. But we must first understand the drivers and lived experience of contemporary, early #adolescent drug use, in order to update and improve our early interventions. onlinelibrary.wiley.com/doi/10.1002/...

onlinelibrary.wiley.com

Prevention, treatment and care of substance use disorders among adolescents. Statement by the UNODC‐WHO Informal Scientific Network, 2024

Click on the article title to read more.

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Will Lawn @willlawn.bsky.social · 21/11/2024

A new longitudinal study from Denmark (n~5,000) has not found any -ve relationship between cannabis use, frequent use, age of initiation and age-related cognition. In fact, men with a history of use had slightly less cog decline from early to midlife decline onlinelibrary.wiley.com/doi/10.1002/...

onlinelibrary.wiley.com

Cannabis Use and Age‐Related Changes in Cognitive Function From Early Adulthood to Late Midlife in 5162 Danish Men

Click on the article title to read more.

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Will Lawn @willlawn.bsky.social · 20/11/2024

Dr Amir Englund has penned a short piece for the Conversation about what we can learn from the legalisation of adult recreational cannabis use in various states in the US and in Canada: theconversation.com/what-are-the...

theconversation.com

What are the lessons from America’s great cannabis liberalisation experiment?

Nearly half of US states allow the recreational use of cannabis.

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Will Lawn @willlawn.bsky.social · 14/11/2024

Prof Ann McNeill's keynote lecture at #SSA2024 was a tour de force. It was disappointing to hear that KCL researchers who promote evidence-based and effective tobacco harm reduction interventions have received harsh international criticism. Vaping isn't safe, but it's far safer than smoking tobacco.

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Will Lawn @willlawn.bsky.social · 14/11/2024

My poster at #SSAConf2024 shows teenagers are at greater risk of problematic use of cannabis vs. adults, after adjusting for genetic predisposition, trauma, SES & gender. But, teenagers are not more vulnerable to impacts of cannabis on depression & anxiety

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Will Lawn @willlawn.bsky.social · 14/11/2024

Sharing a new animation from the science channel @kurzgesagt-bot.bsky.social about the potential risks of heavy, long-term #cannabis use. I helped with scientific content and fact-checking. They have a huge reach on Youtube - good to get a balanced message out www.youtube.com/watch?v=qBRa...

youtube.com

We Have To Talk About Weed

YouTube video by Kurzgesagt – In a Nutshell

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