Ryan West @westwingslab.bsky.social · 13/06/2026I had to physically print and submit 3 paper copies of my PhD thesis. I had to print and post multiple copies of my first fellowship applications. But even this volume of wasted paper is nothing compared to small children’s crafts and drawings 040
Ryan West @westwingslab.bsky.social · 10/06/2026We are pleased that our article on Ataxin-2 and the integrated stress response in C9orf72 ALS/FTD is finally published in full. A lot of hard work from members of the lab, including @comeflywithjo.bsky.social, and our collaborators link.springer.com/article/10.1...link.springer.comTargeting the integrated stress response or Ataxin-2 alleviates neurodegeneration in PolyGR models of C9orf72 associated frontotemporal dementia and amyotrophic lateral sclerosis - Acta Neuropathologi...Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are fatal, early-onset neurodegenerative diseases. The most common genetic cause of FTD and ALS is a G4C2 hexanucleotide repeat ex... 2113
Ryan West @westwingslab.bsky.social · 17/12/2025Moody skies over Sheffield from the office window this morning 030
Ryan West @westwingslab.bsky.social · 10/12/2025Somewhat depleted in numbers due to illnesses half the lab made it out for our annual, rather wet, lab winter walk 030
Ryan West @westwingslab.bsky.social · 20/10/2025I'm looking forward to discussing our work at Tambourine’s ALS Breakthrough Research Fund investigators meeting this week. A pretty good view from my room 020
Ryan West @westwingslab.bsky.social · 12/10/2025taking a break from all the hills and letting the 5 yo loose down the monsal trail 020
Ryan West @westwingslab.bsky.social · 09/09/2025Scott Allen and myself have an opportunity for a postdoc working on pyruvate metabolism in normoxia and hypoxia using a combination of C9orf72 patient-derived iNPC and Drosophila models. Based at SITraN (sheffield.ac.uk/sitran) jobsite.sheffield.ac.uk/job/Research...jobsite.sheffield.ac.ukResearch Associate in C9orf72 ALS metabolic dysfunctionResearch Associate in C9orf72 ALS metabolic dysfunction 010
Reposted by Ryan WestInes Hahn @exdrososcientia.bsky.social · 19/03/2025Check out our new #neuroscience @BiologyatYork banner to showcase our diverse, multidisciplinary, multi model, and so much fun research environment that you could be in by joining us as an under or postgrad york.ac.uk/study/undergra… or/and postgrad too! 072
Reposted by Ryan WestNatalia Sanchez-Soriano @natsansor.bsky.social · 17/01/2025🚀 Hot off the press! Our team findings @livuni-ismib.bsky.social on brain ageing unveil a novel connection between oxidative stress, neuronal microtubules, and the cytoskeletal protein EB1 driving neuronal atrophy. 🎉 A huge thank you to the fantastic team! www.aginganddisease.org/EN/10.14336/...aginganddisease.orgOxidative Stress Promotes Axonal Atrophy through Alterations in Microtubules and EB1 Function<p>Axons are crucial for transmitting neurochemical signals. As organisms age, the ability of neurons to maintain their axons declines; hence, aged axons are more susceptible to damage or dysfunction.... 0146
Ryan West @westwingslab.bsky.social · 24/12/2024I think santa will enjoy the whisky the 4 year old left for him 👀 070
Ryan West @westwingslab.bsky.social · 09/12/2024A birthday card from the lab. A @comeflywithjo.bsky.social special. I wonder what they are trying to imply? 180
Ryan West @westwingslab.bsky.social · 06/12/2024I am pleased we were able to help with this nice paper showing RuvBL1/2 can reduce DPR abundance and reduce phenotypes observed in our fly models www.life-science-alliance.org/content/8/2/...life-science-alliance.orgRuvBL1/2 reduce toxic dipeptide repeat protein burden in multiple models of C9orf72-ALS/FTDA G4C2 hexanucleotide repeat expansion in C9orf72 is the most common cause of amyotrophic lateral sclerosis and frontotemporal dementia (C9ALS/FTD). Bidirectional transcription and subsequent repeat-a... 020
Ryan West @westwingslab.bsky.social · 04/12/2024For anyone heading to #alsmndsymp in montreal look out for @mndassoc.bsky.social funded student Charlotte Gale-Rogers work on C9orf72 DPR disruption to locomotor rhythmicity using some of our fly models. Poster IVV-26. 041
Ryan West @westwingslab.bsky.social · 24/11/2024twitter account deactivated. It's bluesky only now 140
Reposted by Ryan WestJames Catterson @scotsfriction.bsky.social · 19/11/2024🧠Sharing this Starter Pack again as the list has now reached 80 people! A great mix of Profs/PIs/Post-docs/PhDs/Technicians. Please re-post so it can reach a wider audience as I'm sure there are more of us out there ☺️🦋 go.bsky.app/S6FfsTp 02828
Reposted by Ryan WestRyan West @westwingslab.bsky.social · 18/11/2024 a quick trip down to London for a grant panel and to say hello to some old friends 241
Ryan West @westwingslab.bsky.social · 19/11/2024back from a very enjoyable @nc3rs.bsky.social Partnership and Impact panel meeting. Lots of great science. Looking forward to seeing some of those projects going forward. 020
Reposted by Ryan WestAndreas Prokop @poppi62.bsky.social · 18/11/2024Green, M. M. (2010) 2010: A century of #Drosophila genetics through the prism of the 'white' gene. Genetics 184, 3-7 — www.ncbi.nlm.nih.gov/pubmed/20061...ncbi.nlm.nih.gov2010: A century of Drosophila genetics through the prism of the white gene - PubMedIn January 1910, a century ago, Thomas Hunt Morgan discovered his first Drosophila mutant, a white-eyed male (Morgan 1910). Morgan named the mutant gene white and soon demonstrated that it resided on ... 065
Ryan West @westwingslab.bsky.social · 18/11/2024 a quick trip down to London for a grant panel and to say hello to some old friends 241
Reposted by Ryan WestAli Twelvetrees @dozenoaks.bsky.social · 11/11/2024Trying for a molecular and cellular neurobiology starter pack - happy to add folks and connect :) #neuroskyance #cellbiology go.bsky.app/PgEk7aF 477644
Reposted by Ryan WestAngie Serrano @mangieserrano.bsky.social · 16/11/2024As PIs we can mentor our team to select colorblind friendly pseudo colors at acquisition time 🔬and share free (and super cool) resources like colororacle.org and medialab.github.io/iwanthue/ that helps you select or design color friendly palettes for projects that have many categories 💻 #dataVizcolororacle.orgColor Oracle | Color Oracle 162
Reposted by Ryan WestEsther Verheyen 🇨🇦 @estherverheyen.bsky.social · 16/11/2024If you're not sure which Starter Packs you've been added to, you can check them on clearsky.app That's where I found the ones that I'm part of. Wish we could get notified when added to a pack @bsky.app ? 1111
Reposted by Ryan WestEsther Verheyen 🇨🇦 @estherverheyen.bsky.social · 15/11/2024My starter pack is growing! Please reach out if you use animal models (flies, worms, mice, fish, etc) to study disease mechanisms and want to be added. go.bsky.app/MhUwjSx 7814560
Reposted by Ryan WestJack Bateman @jbateman01.bsky.social · 12/11/2024I thought we could use a Drosophila starter pack, please let me know if you’d like to be added. (I think there is also a more general insect list out there somewhere that i cant find rn..) go.bsky.app/JGggkH3 756839
Reposted by Ryan WestDementia Researcher @dementiaresearcher.bsky.social · 14/11/2024Professor Kurt De at The University of Sheffield is looking for a Research Associate investigating ALS / FTD caused by mutations in the C9orf72 gene. Closing date: 21st November. www.dementiaresearcher.nihr.ac.uk/job/research...dementiaresearcher.nihr.ac.ukResearch Associate: C9orf72 haploinsufficiencyProfessor Kurt De Vos at The University of Sheffield is looking for a Research Associate investigating ALS / FTD caused by mutations in the C9orf72 gene 021