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Vojtech Dvorak

@vojtechdvorak.bsky.social
60 followers 73 following 2 posts

Chemical biologist & drug hunter, keen on membrane transporters and metabolism

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Vojtech Dvorak @vojtechdvorak.bsky.social · 26/11/2025
www.science.org/content/blog...
science.org
Reverse Proteolysis, Will You Look At That
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Reposted by Vojtech Dvorak
Open Box Science @openboxscience.bsky.social · 02/06/2025
OBS SPEAKER HIGHLIGHT👩‍🔬 How Skin Injury Primes Distant Immunity 🗣️ @mariemradhouani.bsky.social @starkllab.bsky.social lab.bsky.social @cemm-vienna.bsky.social @meduniwien.ac.at 📆 Thu, June 5, 11 pm ET 👉 Registration: us02web.zoom.us/meeting/regi...
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Vojtech Dvorak @vojtechdvorak.bsky.social · 25/05/2025
Even though this essay is supposedly a classic, I only discovered it a few days ago. It’s a great (short) read, indeed! www.cell.com/cancer-cell/...
cell.com
Can a biologist fix a radio?—Or, what I learned while studying apoptosis
As a freshly minted Assistant Professor, I feared that everything in my field would be discovered before I even had a chance to set up my laboratory. Indeed, the field of apoptosis, which I had recent...
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Reposted by Vojtech Dvorak
giuliosupertifurga.bsky.social @giuliosupertifurga.bsky.social · 19/05/2025
Paper(s) alert from our RESOLUTE project – In a compilation of four papers in @molsystbiol.org we show how we were deciphering cellular logistics and present a comprehensive systematic blueprint of chemical transport pathways with #SoluteCarrier transporters
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Reposted by Vojtech Dvorak
Savitski Lab @savitski-lab.bsky.social · 29/04/2025
Want to know how the ligands interact with proteins beyond model cell lines, e.g., in tissues or bacteria? Interested in membrane targets? Check out our High-Throughput PELSA method which allows you do all these cool screenings for dozens of ligands within two hours! www.biorxiv.org/content/10.1...
biorxiv.org
High-throughput peptide-centric local stability assay extends protein-ligand identification to membrane proteins, tissues, and bacteria
Systematic mapping of protein-ligand interactions is essential for understanding biological processes and drug mechanisms. Peptide-centric local stability assay (PELSA) is a powerful tool for detectin...
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Reposted by Vojtech Dvorak
Mariem Radhouani @mariemradhouani.bsky.social · 04/04/2025
I'm excited to share my first-author PhD paper, now out in Science Immunology! @science.org We show that S.aureus skin infection leaves a lasting imprint on bone marrow eosinophils, fueling allergic responses in the lungs. 📄 Read the full study: www.science.org/doi/10.1126/... Let’s dive in 🧵 1/9
science.org
Eosinophil innate immune memory after bacterial skin infection promotes allergic lung inflammation
Staphylococcus aureus skin infection induces eosinophil innate immune memory to exacerbate allergen-induced airway inflammation.
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Reposted by Vojtech Dvorak
Christian Frezza @frezzalab.bsky.social · 01/02/2025
Lactate homeostasis is maintained through regulation of glycolysis and lipolysis: Cell Metabolism www.cell.com/cell-metabol...
cell.com
Lactate homeostasis is maintained through regulation of glycolysis and lipolysis
Lactate elevations are a hallmark of human disease, but the mechanisms regulating lactate levels remain poorly understood. Here, Lee et al. elucidate the mechanisms of lactate homeostasis. These invol...
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Reposted by Vojtech Dvorak
Chemical Probes Portal @chemicalprobes.org · 28/01/2025
🔬 Calling all PhD students & postdocs in chemistry/biology! Join us at the Chemical Probes Hackathon 🧪: 🗓️ Feb 20, 2025 | 10:00–14:30 📍 Vienna, Austria 💡 Evaluate chemical probes w/ experts & improve global science 🌍. 🎓 Earn a Certificate of Attendance! Learn more & register 👇
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Reposted by Vojtech Dvorak
Superti-Furga Lab @supertifurgalab.bsky.social · 07/01/2025
Kicking off the new year: A collaboration between @giuliosupertifurga.bsky.social and @alessiociulli.bsky.social using a transporter-focused genetic screens revealed that the efflux pump ABCC1/MRP1 restricts PROTAC sensitivity in cancer cells. Out now in @CellChemBiol www.cell.com/cell-chemica...
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