iiinova — where your digital self keeps evolving

Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 18/03/2026

We're proud to announce Baylor College of Medicine as the first customer of our Iterative Mapping Early Access Program! www.globenewswire.com/news-release...

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 24/11/2025

Join us on Jan 14 at 9am PT for an exclusive webinar on Iterative Mapping, our single-molecule proteomics method for precise, AI-ready protein quantification. 🗣️Speakers - Dr. Parag Mallick, Dr. Sheri Wilcox, and Dr. Birgit Schilling Register now: www.selectscience.net/webinar/adva...

selectscience.net

Advancing next-generation proteomics with single-molecule Iterative Mapping

Join our webinar on Wednesday, January 14 to explore Iterative Mapping, a cutting-edge single-molecule proteomics method. Learn how it delivers precise, quantitative analysis of proteins and proteofor...

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 21/11/2025

Access the recording of our #HUPO2025 seminar to see how Professor Birgit Schilling from the @buckinstitute.org is using the Nautilus Platform to explore the tau proteoform landscape across brain regions in a mouse model of Alzheimer's disease. nautilus-21430832.hs-sites-na2.com/download-hup...

nautilus-21430832.hs-sites-na2.com

Fill out the form to receive a recording of our HUPO 2025 lunch seminar.

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 30/10/2025

Today on the Nautilus Blog - The second post in our new series focused on #AI and #proteomics. Dive in to learn how our data’s quality, simple and direct relationship to biology, and scale are designed to make it ideal for AI integration. www.nautilus.bio/blog/why-is-... #ML #Proteome

nautilus.bio

Why is Nautilus data well-suited for AI workflows?

Discover how Nautilus data is designed to provide direct and detailed measurements of single protein molecules that are well-suited for AI workflows.

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 10/10/2025

Earlier this week, our own Co-Founder and Chief Scientist Parag Mallick joined a panel at Fierce Biotech Week to discuss, "How Biotechs Are Leveraging AI/ML to Drive Efficiency and ROI." Three intriguing takeaways from the panel can be found in the thread below 🔽 #Proteomics #Biotech #AI

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 01/10/2025

Next Thursday, October 9th at 11:15am ET, Nautilus Co-Founder and Chief Scientist Parag Mallick will join a panel at Fierce Biotech Week to discuss: 🗣️ How Biotechs Are Leveraging AI/ML to Drive Efficiency and ROI www.fiercebiotechweek.com/event/fierce... #ArtificialIntelligence #MachineLearning

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 25/09/2025

In the latest update to our Proteomics and cancer eBook, you'll find content focused on the incredible ways proteoform analysis can advance cancer research. 📘 Find the eBook here: www.nautilus.bio/blog/applica... #Proteoforms #Proteome #Proteomics #Cancer #CancerResearch #PrecisionMedicine

nautilus.bio

Applications of proteomics in cancer - Round up September 2025 ~ Nautilus Biotechnology

Find Nautilus' latest applications of proteomics in cancer content focusing the impact proteoform analysis can have on cancer research

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 11/09/2025

We were honored to meet with leaders in #proteoform research at #CTDP2025 last month. We are excited to work with this community to advance all #lifeSciences #research through the power of proteoforms. Learn more: www.nautilus.bio/blog/making-...

nautilus.bio

Making proteoforms mainstream with the Consortium for Top-Down Proteomics

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Tyler Ford @tyfordfever.bsky.social · 04/09/2025

Researchers are beginning to use the Nautilus Platform to do great things! Resources covering why knowledge of #proteoforms may change how we approach diseases like Alzheimer's in thread ⬇️ #AlzheimersDisease #Proteomics

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Tyler Ford @tyfordfever.bsky.social · 28/08/2025

Only #proteomics could explain how the "X-gene" gives rise to all the different mutant powers in X-Men!

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 21/08/2025

A desire to forge connections drives Nicole Newland, SHRM-CP in her role as an HR Operations Generalist at Nautilus. From recruiting to updating #HR systems and beyond, read our latest #LifeAtNautilus blog post to discover how Nicole's drive helps Nautilus grow. www.nautilus.bio/blog/life-at...

nautilus.bio

Life at Nautilus Interview with Nicole Newland - Senior HR Operations Generalist

Discover how a drive for connection led Nicole Newland to study psychology and later translated into a fulfilling career in HR at Nautilus.

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 15/08/2025

Have questions about the Nautilus Proteome Analysis Platform? Nautilus co-founder and chief scientist Parag Mallick has answers! Find them here: youtu.be/IUNVCNDhajk?... #Nautilus #NautilusBiotechnology #Proteomics #NextGenerationProteomics #Proteoforms #Proteoform #Biotech #Biotechnology

youtu.be

Parag answers questions about the Nautilus Proteome Analysis Platform

YouTube video by Nautilus Biotechnology

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 06/08/2025

We're proud to be featured in this @natmethods.nature.com thods.nature.com article covering up-and-coming single-molecule #proteomics platforms! www.nature.com/articles/s41... We're developing an "entirely new measurement modality" & look forward to mapping the #proteome and #proteoform landscape.

nature.com

Is single-molecule protein sequencing here yet? - Nature Methods

As instruments and approaches emerge for single-molecule protein analysis, some developers and early users share their first impressions.

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 04/08/2025

When we solicited questions about #proteomics for an episode of #TranslatingProteomics, we got many queries about the Nautilus Platform. So, we answered as many as we could in this video! youtu.be/IUNVCNDhajk?... #Biotech #Biotechnology #Research #ResearchAndDevelopment #Proteoforms

youtu.be

Parag answers questions about the Nautilus Proteome Analysis Platform

YouTube video by Nautilus Biotechnology

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 31/07/2025

You asked, we answered! Our latest episode of #TranslatingProteomics features answers to pressing #proteomics questions submitted by the community. Don Kirkpatrick even makes a surprise appearance to discuss how proteomics plays a powerful role in #drugDevelopment. www.nautilus.bio/blog/transla...

nautilus.bio

Translating Proteomics "Ask me anything" episode featuring special guest Don Kirkpatrick

Parag Mallick, Andreas Huhmer, and special guest Don Kirk Patrick answer questions from the Translating Proteomics community.

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Tyler Ford @tyfordfever.bsky.social · 30/07/2025

Very excited for our agreement with the Allen Institute!

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 28/07/2025

Interested in diving into our poster from #AAIC 2025? Sign up to receive a digital copy of the poster at the link below ⤵️ nautilus-21430832.hs-sites.com/download-nau... #Proteomics #Proteoforms #Proteome #Neuroscience

nautilus-21430832.hs-sites.com

Download Nautilus' Poster from AAIC 2025

Fill out this form download Nautilus Biotechnology's poster form AAIC 2025.

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 15/07/2025

Learn how Iterative Mapping of proteoforms on the Nautilus Proteome Analysis Platform provides uniquely actionable views of the proteoform landscape: www.nautilus.bio/blog/iterati... #Proteomics #Proteome #Proteoform #Proteoforms #NextGenerationProteomics #Alzheimers #AlzheimersDisease

nautilus.bio

Iterative Mapping provides in-depth views of proteoform groups

Discover the benefits of proteoform group analysis by Iterative Mapping.

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 10/07/2025

In our latest blog post, discover how Iterative Mapping achieves in-depth #proteoform group analysis. We walk through a theoretical example showing why the method is so unique and provide a sneak peek at data demonstrating its power. www.nautilus.bio/blog/iterati... #Proteomics #Biotechnology

nautilus.bio

Iterative Mapping provides in-depth views of proteoform groups

Discover the benefits of proteoform group analysis by Iterative Mapping.

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Tyler Ford @tyfordfever.bsky.social · 08/07/2025

The latest Nautilus Newsletter is huge! Read our tau proteoform preprint, dive into the preprint data in our webinar, meet with us at #AAIC2025 to learn more, and find a fascinating interview with #spatialProteoomics pioneer Fiona Ginty!

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Tyler Ford @tyfordfever.bsky.social · 01/07/2025

In this blog series, we walk through some of the data from our recent preprint, highlight some of the rationale for working with tau as an exemplar, and discuss some of the possibilities enabled by proteoform analysis. I'd love to hear how you think proteoform analysis can advance your work!

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 30/06/2025

Explore our new preprint featuring novel data generated on the Nautilus Proteome Analysis Platform! The preprint covers how we use Iterative Mapping to quantify tau proteoforms at the single-molecule level: www.biorxiv.org/content/10.1... #Proteomics #Neuroscience #Proteoforms #AlzheimersDisease

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 25/06/2025

Discover how the Nautilus Proteome Analysis Platform is designed to enable researchers to explore the "dark proteome" in this article featuring insights from Nautilus Co-Founder and Chief Scientist Parag Mallick. www.selectscience.net/article/sing...

selectscience.net

Single-molecule proteomics platform reveals biology’s hidden players

Scalable single-molecule analysis could uncover low-abundance proteins and proteoforms critical for understanding complicated disease networks and therapeutic response

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Tyler Ford @tyfordfever.bsky.social · 19/06/2025

This is definitely one of my favorite episodes of Translating Proteomics so far. Andreas Huhmer and Sarah DeVos provide a great summary of the landscape of Alzheimer's research, biomarkers, therapeutics, and why now is such an exciting time in this space.

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 16/06/2025

Register for our upcoming webinar to discover how the Nautilus Proteome Analysis Platform enables the investigation of THOUSANDS of tau proteoforms and their roles in #AlzheimersDisease and other tauopathies. Register here: www.selectscience.net/webinar/brin... #Proteomics #Neurodegeneration

selectscience.net

Webinar: Single-molecule proteome and proteoform analysis

Join our webinar to discover how single-molecule proteomic analysis improves scale, sensitivity, and resolution. Learn about measuring 2,048 tau proteoforms in Alzheimer’s disease models.

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Tyler Ford @tyfordfever.bsky.social · 09/06/2025

How is the Nautilus Proteome Analysis Platform already being used to gain insights into Alzheimer's and other tauopathies? Attend our upcoming webinar to find out! #Neuroscience #AlzheimersDisease #Tau #Neurodegeneration #Proteomics

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Tyler Ford @tyfordfever.bsky.social · 05/06/2025

The more I read and write about proteoforms, the more I'm convinced of their importance. Measuring "protein" levels is critical, but can obscure what's happening at the functional, proteoform level as is clear in the work discussed here. #Proteomics #Proteoforms #Cancer

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Tyler Ford @tyfordfever.bsky.social · 29/05/2025

Among the many cool things I learned from this episode - Fiona's collaborators included someone working on geospatial mapping. Their expertise helped make it possible to identify cells in pathology images. Such a cool example of the importance of cross-disciplinary teams!

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 22/05/2025

Proteomics can redefine how we make, grow, and even taste food. Check out this blog post covering a recent episode of the #TranslatingProteomics podcast to discover how proteomics may impact #foodScience and production. www.nautilus.bio/blog/proteom... #Proteomics #FoodTech #Food #Biotech #Podcast

nautilus.bio

Proteomics and the food of the future

Learn how proteomics may change the future of food.

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Tyler Ford @tyfordfever.bsky.social · 20/05/2025

Have question about #proteomics, it's applications, and the future of the field? Send them over to us, and we may answer them on the Translating Proteomics podcast!

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 19/05/2025

For an inside look at how AI pioneers and investors Vijay Pande, PhD and Matt McIlwain are thinking about the role of AI in biology, listen to this episode of the #TranslatingProteomics podcast: www.nautilus.bio/blog/transla... #Biotech #Podcast #AI #Proteomics

nautilus.bio

Translating Proteomics Episode 13 - AI and Biotech: The Promise and the Pitfalls with Vijay Pande and Matt McIlwain

Parag Mallick discusses the promises and pitfalls of AI in biotech with special guests Vijay Pande and Matt McIlwain.

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 15/05/2025

We often think about the ways individual PTMs change signaling, but it's likely patterns of modification on #proteoforms that matter. Find evidence suggesting this may be the case for #EGFR in our latest blog post featuring 2010 work from Forest White's Lab at MIT. www.nautilus.bio/blog/proteof...

nautilus.bio

Proteoforms and EGFR signaling – Applications of proteomics in cancer

Learning more about EGFR proteoforms may help us understanding and treat cancer.

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 08/05/2025

Denise Miller helped build surgical robots. Now she's applying her skills to proteomics at Nautilus where she hopes our technology will enable researchers to go beyond treatments and develop cures. Read her story: www.nautilus.bio/blog/life-at... #SoftwareEngineering #Proteomics #CareersInSTEM

nautilus.bio

Life at Nautilus Interview with Denise Miller - Associate Director of Software Engineering

Learn why Denise Miller, Associate Director of Software Engineering, is excited to use her expertise to help build the Nautilus Platform.

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Reposted by Tyler Ford

Derek Lowe @dereklowe.bsky.social · 07/05/2025

So, how many genetic diseases come down to good ol’ loss-of-function in the targeted protein? Your estimate is probably too high:

science.org

Mutant Proteins Classified

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 23/04/2025

Need a brief introduction to proteomics? Look no further than this video: youtu.be/we9-twPhpB4 #Proteomics #Proteome #TranslatingProteomics

youtu.be

Intro to Proteomics

YouTube video by Nautilus Biotechnology

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 17/04/2025

New to proteomics? In our latest #TranslatingProteomics episode, Andreas & Parag break down the basics—perfect for anyone with a molecular biology background looking to get started. 🎧 Listen here: www.nautilus.bio/blog/intro-t... #Proteomics #IntroToProteomics #Proteome #Proteomics101

nautilus.bio

Intro to Proteomics

Listen to this episode of Translating Proteomics for a refresher on the basics of proteomics or to get started in the field.

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 10/04/2025

Check out our interview with Nautilus Senior Scientist Michael Darcy to learn what it's like to combine scientist and engineering as we develop a whole new way to do proteomics: www.nautilus.bio/blog/life-at... #Proteomics #Biotech #Engineering #ScienceCareers #CareersInSTEM

nautilus.bio

Life at Nautilus Interview with Michael Darcy Ph.D. - Senior Scientist

Nautilus Senior Scientist Michael Darcy shares why he's exciting to work a an entirely new way to do proteomics.

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Tyler Ford @tyfordfever.bsky.social · 03/04/2025

I serendipitously had a conversation about #AI and #Biotech with some friends at dinner yesterday and working on this blog post with @jtsangwrites.bsky.social really helped frame my thoughts!

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 31/03/2025

On #TranslatingProteomics, Parag Mallick highlights advances in the scale and application of #proteomics in #biomedicine (with shout-outs to Forest White and @markcblaser.bsky.social) as two things he was particularly impressed by at #USHUPO. Full episode: www.nautilus.bio/blog/us-hupo...

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 27/03/2025

On this episode of #TranslatingProteomics, Andreas Huhmer and Parag Mallick share their recent experiences at #USHUPO. They discuss exciting takeaways, trends, and the future of #proteomics through the lens of the conference. Check it out here: www.nautilus.bio/blog/us-hupo...

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Reposted by Tyler Ford

Jennifer Tsang @jtsangwrites.bsky.social · 24/03/2025

When patients come into the hospital with a life-threatening infection, doctors start treatment with broad-spectrum antibiotics before understanding exactly what microbe they're dealing with and what antibiotics can kill it. New methods can change that.

drugdiscoverynews.com

Diagnostics for faster antimicrobial susceptibility testing

New phenotypic methods can help identify the best antibiotic to treat sepsis, UTIs, and other bacterial infections.

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Reposted by Tyler Ford

Carolyn Bertozzi @carolynbertozzi.bskyverified.social · 23/03/2025

Great piece by the legendary Francis Arnold @caltech.edu @nobelprize.bsky.social on the occasion of receiving the Priestley Medal this week at #ACSSpring2025

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 24/03/2025

One of our most popular episodes of #TranslatingProteomics focuses on the need to understand biology is space and time. Check it out to learn why we need to make movies of biology: youtu.be/kxezVEXNg88?... #Science #Podcast #Proteomics #Biology

youtu.be

Biology in Space and Time: Translating Proteomics Episode 3

YouTube video by Nautilus Biotechnology

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Tyler Ford @tyfordfever.bsky.social · 20/03/2025

The research behind the paper discussed here provides strong evidence that studying tau proteoforms may lead to new #biomarkers and #precisionMedicines. I'm very excited about the potential fruits from this kind of research. Many thanks to @jtsangwrites.bsky.social for help editing this post!

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 18/03/2025

Learn how Alzheimer's biomarkers have changed Alzheimer's research and how new blood-based biomarkers can drive the field even further in this clip from Translating Proteomics featuring Sarah DeVos of Curie.Bio. www.youtube.com/watch?v=vD2Q... #Alzheimers #Biomarkers #Podcast

youtube.com

A New Era in Alzheimer's Research with Sarah DeVos: Translating Proteomics Episode 12

YouTube video by Nautilus Biotechnology

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 14/03/2025

Scientists are much more than folks in lab coats doing experiments. On #TranslatingProteomics, Parag, @benneely.com, and @proteomicsnews.bsky.social discuss how every scientist is interesting - a fact that shouldn't be overlooked in #scienceCommunication. www.youtube.com/watch?v=zIJK...

youtube.com

Science Communication and Proteomics - Benefits, Barriers, & Solutions with Ben Neely & Ben Orsburn

YouTube video by Nautilus Biotechnology

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 13/03/2025

From heart cells beating in a dish to single protein molecules, learn how Nautilus Software Engineer Winnie Leung leverages her image processing and analysis capabilities to advance biology. www.nautilus.bio/blog/life-at... #Proteomics #Biotech #Imaging #SoftwareEngineering #ScienceCareer

nautilus.bio

Life at Nautilus interview with Winnie Leung – Software Engineer

Nautilus software engineer Winnie Leung describes how she leverages her image analysis expertises to help develop the Nautilus Platform.

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Reposted by Tyler Ford

Nautilus Biotechnology @nautilus.bio · 11/03/2025

#Proteomics is advancing rapidly! Parag and Andreas share 3 of their favorite examples of proteomics research from 2024 here, and we'd love to hear about yours! Share them in the replies and we may cover them in a future episode. youtu.be/LqTO42Vf1H4?... #TranslatingProteomics

youtu.be

Translating Proteomics 2024 Year-End Special: 3 Exciting Examples of Proteomics Research

YouTube video by Nautilus Biotechnology

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