iiinova — where your digital self keeps evolving

Travis Goode @travisgoode.bsky.social · 01/09/2026

🧪🧪🧪 (1/5) Beyond thrilled to announce that I’ll be starting my own lab as a Tenure-Track Assistant Professor at the University of Tennessee Health Science Center (@uthsc.bsky.social) in Jan 2027! #NewPI My lab will study the neurobiology of learning, memory, and motivation! 🧠🐭⚡️🔬

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Amar Sahay @amarsahay.bsky.social · 12/08/2026

Explore our XPG NDD portal: xpg-atlas.onrender.com And share feedback and your thoughts after you come up for air from a dive into the study. Thx

xpg-atlas.onrender.com

XPG Atlas

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Travis Goode @travisgoode.bsky.social · 12/08/2026

Very happy to see this incredible and rigorous work out now in @nature.com! Yu-Tzu and Jason are amazing people and scientists—so well deserved! Congrats to the superb team! 🧠🧠🧠🧪🧪🧪

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The Transmitter @thetransmitter.bsky.social · 12/08/2026

Experience-dependent interneuron plasticity may represent a convergent circuit mechanism for these neurodevelopmental risk genes that reflects a shared genetic architecture, a new study suggests. By @claudia-lopez.bsky.social www.thetransmitter.org/spectrum/los...

thetransmitter.org

Neurodevelopmental conditions may share faulty plasticity

Restoring expression of an experience-dependent interneuron plasticity gene aids memory and cuts seizures in CNTNAP2 knockout mice, a new study shows.

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 27/07/2026

How visual scenes recruit spatial maps: threshold-gated activation in CA3 versus continuous integration in CA1 www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 27/07/2026

Pharmacogenetic manipulation of Locus coeruleus activity in monkeys demonstrates its role in cognitive effort www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 29/07/2026

Beyond Temporary Scaffolding: Persistent Hippocampal Engagement and Brain-Wide Network Reorganization in Remote Memory Consolidation www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 30/07/2026

A conserved population of genetically defined striatal neurons gates opioid reward www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 30/07/2026

Hunger neurons track available food locations during foraging and spatial memory recall www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 31/07/2026

A Neurotensin Brake on Exploratory Drive under Persistent Threat www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 31/07/2026

Memory encoding reprograms neuronal transcriptional responses via durable chromatin remodeling www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 31/07/2026

Striatal acetylcholine enables latent-state creation during reversal learning www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 09/07/2026

Hippocampal CA3 forms a two-layer network of molecularly distinct cell types in mice and humans www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 03/07/2026

A cholinergic eligibility trace facilitates amygdala plasticity in flavour avoidance learning www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 06/07/2026

Kappa opioid receptors (KORs) in the anterior paraventricular nucleus of the thalamus (aPVT) mediate morphine withdrawal-, anxiety-, fear-, and KOR agonist-induced aversion-like behaviors in mice www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 07/07/2026

Hippocampal engrams configure prefrontal context representations to guide flexible decisions www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 07/07/2026

Opposing GIPR brainstem circuits differentially control feeding behaviour www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 08/07/2026

The emergence of a novel CA1 spatial map requires direct entorhinal input www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 27/06/2026

Old mice fail to integrate a memory update into an existing hippocampal engram. www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 27/06/2026

Hippocampal-cortical coupling dynamics drive system consolidation of remote memory www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 28/06/2026

Arousal state modulates human hippocampal ripples www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 28/06/2026

The genetic signature of memory encoding along the human hippocampal axis www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 29/06/2026

The prefrontal cortex outputs to the amygdala facilitate threat-discrimination learning www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 30/06/2026

Long-range inhibitory control of cholinergic network dynamics in the striatum. www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 30/06/2026

Time cells lead neural reinstatement of episodic memory www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 01/07/2026

Hippocampal microcircuits constrain the generation of epileptiform activity www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 22/06/2026

Human dental pulp stem cells grafted into C57BL/6J hippocampus differentiate towards immature neuronal like cells displaying action potential firing activity www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 23/06/2026

Valence-specific representation of uncertainty in the anterior cingulate is impaired in those with affective symptoms www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 23/06/2026

A multi-organ spatial metabolomic atlas of exercising mice reveals neuronal Complex I as a convergent and sufficient axis for tau pathology reduction in PS19 www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 23/06/2026

A human intracranial map of consciousness returning from anesthesia www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 23/06/2026

Individual differences in ethanol drinking meal structure are shaped by social environments www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 23/06/2026

Reduced dopaminergic reinforcement, not learning capacity, limits operant learning in aging Drosophila www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 23/06/2026

Multisensory integration of stimulus-driven and goal-driven signals during urgent saccadic choices www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 23/06/2026

Ventral pallidal GABAergic neurons control hedonic feeding and obesity www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 05/06/2026

Hippocampal consummatory reward ensembles dynamically engage theta-SWR states during spatial working memory www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 07/06/2026

Hippocampal CA2 modulates trace fear conditioning through circuit-specific control of CA1 www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 10/06/2026

Dissecting the Role of the Lateral Entorhinal Cortex in Memory Interference www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 10/06/2026

GABAergic projection from the subiculum to the medial entorhinal cortex in mice and rats www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 10/06/2026

Dynorphinergic neuroadaptations in the islands of Calleja: implications for alcohol use disorder www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 10/06/2026

Hippocampus-evoked polysynaptic responses in the medial prefrontal cortex are attenuated in aged rats. www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 11/06/2026

Hypothalamic Representation of Aggressiveness across Mouse Strains www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 12/06/2026

Anatomical organization and origins of VGLUT3-positive axon terminals in the lateral septum. www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 13/06/2026

Interplay of sleep neural oscillations enhances coordinated memory reactivation between cortex and hippocampus www.biorxiv.org/content/10.64898/20…

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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 14/06/2026

The Amygdalostriatal Transition Area Exhibits Lateral Amygdala-Like Spiking Activity and Tone-Shock Pairing-Induced Plasticity www.biorxiv.org/content/10.64898/20…

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Amar Sahay @amarsahay.bsky.social · 05/06/2026

Celebrating milestones on this journey with this great group of scientists. Engaged & excited about discoveries even with the assault on science at all levels. @travisgoode.bsky.social @jasonalipio.bsky.social @aloknm.bsky.social and Yu-Tzu S, Cinzia V, Iyanah M and Trey M, not on platform.

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Travis Goode @travisgoode.bsky.social · 12/02/2026

Restaurants, billboards, commercials… what brain circuits link context to appetite? 🧠🌎🍽️ Very happy to finally share a major update in our work exploring the hippocampus and lateral septum in calibrating food consumption! 🍩 Major thanks to our lab and collaborators! ⭐️⭐️ www.cell.com/neuron/fullt...

cell.com

A dorsal hippocampus-prodynorphinergic dorsolateral septum-to-lateral hypothalamus circuit mediates contextual gating of feeding

Goode et al. show that prodynorphin (Pdyn)-expressing neurons of the dorsolateral septum (DLS) receive substantial dorsal hippocampal (DHPC) input and inhibit lateral hypothalamic (LHA) GABAergic neur...

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