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Translucence Biosystems @translucencebio.bsky.social · 10/09/2026

We are excited to announce that we are entering a strategic partnership with Bruker Fluorescence Microscopy to make whole-organ 3D imaging more accessible to the greater scientific community. (1/🧵)

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Translucence Biosystems @translucencebio.bsky.social · 09/09/2026

Kit user highlight! The sample shown in the attached video was generated by Jenna McCloskey at The Ohio State University using a Translucence Biosystems Universal Tissue Clearing Kit. This video shows ΔFosB-positive cells across an intact rat brain hemisphere.

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Translucence Biosystems @translucencebio.bsky.social · 20/08/2026

Coming up in less than two weeks: Join us at @ucberkeleyofficial.bsky.social for a Tissue Clearing Lunch ‘n’ Learn, presented in collaboration with the Cancer Research Laboratory’s Molecular Imaging Center.

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Translucence Biosystems @translucencebio.bsky.social · 19/08/2026

This 3D visualization, captured on a #Zeiss lightsheet, shows Aquaporin-2 (AQP2) and smooth muscle actin (SMA) staining across an intact mouse kidney cleared with our Universal Tissue Clearing Kit!

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Translucence Biosystems @translucencebio.bsky.social · 07/08/2026

This video highlights the power of tissue clearing and lightsheet imaging for providing deeper, spatially resolved insights in biological research.

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Translucence Biosystems @translucencebio.bsky.social · 05/08/2026

Coming up next month: Join us at @ucberkeleyofficial.bsky.social for a Tissue Clearing Lunch ’n’ Learn, presented in collaboration with the Cancer Research Laboratory’s Molecular Imaging Center.

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Translucence Biosystems @translucencebio.bsky.social · 01/07/2026

We love supporting and engaging with the next generation of scientists! Today at 1 PM, Director of Products and Business Development, Nathaniel Guansona, is speaking at University Lab Partners' Meet the Scientist series.

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Translucence Biosystems @translucencebio.bsky.social · 17/06/2026

Tune in tomorrow for the Brainsight Breakthroughs webinar from ZEISS Microscopy featuring Melissa Cooper, PhD, and her recent work on astrocyte networks across the intact brain.

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Translucence Biosystems @translucencebio.bsky.social · 05/06/2026

June is Alzheimer’s and Brain Awareness Month, a time to recognize the impact of Alzheimer’s disease and the importance of continued progress in brain research.

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Translucence Biosystems @translucencebio.bsky.social · 27/05/2026

This video shows β-tubulin labeling across a cleared mouse embryo, highlighting cellular and cytoskeletal organization throughout the intact specimen.

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Translucence Biosystems @translucencebio.bsky.social · 15/05/2026

cFos has been used for decades to map neuronal activity, however its expression is not a direct readout of neuronal activity, as cFos expression can be induced by broader signaling pathways, including cAMP-dependent pathways, neurotrophins, and other paracrine factors.

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Translucence Biosystems @translucencebio.bsky.social · 13/05/2026

We are excited to attend the ASGCT 2026 Annual Meeting in #Boston this week, from May 11th to 15th. @asgct.bsky.social brings together the global cell and gene therapy community across scientific, translational, and regulatory areas to help advance these critical therapeutic areas.

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Translucence Biosystems @translucencebio.bsky.social · 09/05/2026

Happy #FluorescenceFriday! This visualization shows a cleared whole-mouse spinal cord with left and right motor cortex neurons labeled in different fluorescent colors and traced continuously down the intact spinal cord in 3D.

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Translucence Biosystems @translucencebio.bsky.social · 06/05/2026

On Monday, Translucence Biosystems attended the rally in Sacramento, CA, in support of SB 895, the California Science and Health Research Bond Act.

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Translucence Biosystems @translucencebio.bsky.social · 30/04/2026

This 2D pan-through from a 3D light-sheet dataset shows a cleared mouse brain hemisphere stained for human IgG (red) and amyloid plaques (green).

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Translucence Biosystems @translucencebio.bsky.social · 22/04/2026

This side-by-side 2D view of a cleared kainic acid–induced seizure mouse hemisphere shows #Npas4 immunoreactivity in green and #cFos immunoreactivity in red. At baseline, Npas4 expression is minimal, while cFos exhibits relatively high baseline levels of expression.

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Translucence Biosystems @translucencebio.bsky.social · 18/04/2026

Happy #FluorescenceFriday! Here is another look at how tissue clearing can support the evaluation of novel human antibody therapeutics for CNS-related diseases.

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Translucence Biosystems @translucencebio.bsky.social · 09/04/2026

This visualization shows whole-brain tyrosine hydroxylase (TH) staining in a cleared mouse brain, revealing dopaminergic neuron cell bodies and projections at cellular resolution throughout the intact brain.

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Translucence Biosystems @translucencebio.bsky.social · 03/04/2026

The data in this video highlights the power of tissue clearing for evaluating novel human antibody therapeutics for CNS-related disorders.

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Translucence Biosystems @translucencebio.bsky.social · 27/03/2026

Happy #FluorescenceFriday! Today we are excited to share this video which shows a cleared mouse brain hemisphere following depletion of endogenous microglia and transplantation of human cells (magenta).

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Translucence Biosystems @translucencebio.bsky.social · 25/03/2026

We had a great time at AD/PD™ 2026 in #Copenhagen, engaging with researchers driving advances in neurodegenerative disease research!

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Translucence Biosystems @translucencebio.bsky.social · 19/03/2026

Today, we are presenting two posters at AD/PD™ 2026. Poster #3404 examines whole-brain measurement of plaques, microglia, α-synuclein, and tyrosine hydroxylase in AD and PD model mice using tissue clearing, light sheet imaging, and AI-powered quantification.

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Translucence Biosystems @translucencebio.bsky.social · 17/03/2026

Today marks the start of AD/PD™ 2026 in #Copenhagen! We are excited to join the community this week to discuss new approaches for measuring CNS disease pathology and therapeutic distribution across intact brain tissue.

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Translucence Biosystems @translucencebio.bsky.social · 13/03/2026

We are excited to announce our second poster that we will be presenting at AD/PD™ 2026!

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Translucence Biosystems @translucencebio.bsky.social · 12/03/2026

We are excited to announce our first poster that we will be presenting at AD/PD™ 2026!

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Translucence Biosystems @translucencebio.bsky.social · 06/03/2026

For the first Fluorescence Friday of the month, we want to take a moment to recognize Brain Awareness Month and celebrate the researchers and technologies helping us better understand the brain in health and disease.

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Translucence Biosystems @translucencebio.bsky.social · 04/03/2026

Join CEO, Damian Wheeler, and Director of Products and Business Development, Nathaniel Guanzon, at #ADPD2026 as they present recent work applying our brain-wide measurement techniques to the evaluation of CNS therapeutics and disease pathology in intact tissue.

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Translucence Biosystems @translucencebio.bsky.social · 27/02/2026

This dataset shows α-synuclein staining (green) in a cleared mouse brain following direct PFF injection. The video reveals the distribution of α-synuclein fibrils and cell bodies at cellular resolution across the intact brain.

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Translucence Biosystems @translucencebio.bsky.social · 27/02/2026

This dataset shows alpha-synuclein staining in a cleared mouse brain following direct PFF injection. The video reveals the distribution of alpha-synuclein fibrils and nuclei at cellular resolution across the intact brain.

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Translucence Biosystems @translucencebio.bsky.social · 26/02/2026

Your first look at our newest tissue clearing technology, TB.Clear™! Tissue clearing has transformed how we study intact biological systems, but many solvent-based methods (including widely used protocols like iDISCO+) can quench endogenous fluorescence.

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Translucence Biosystems @translucencebio.bsky.social · 13/01/2026

Today was the first day of the FLAIR workshop! Are you or someone you know attending? Be sure to stop by our booth between all of the amazing talks and demos happening between today and Thursday! We are excited to discuss the ways we can support your research.

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Translucence Biosystems @translucencebio.bsky.social · 08/01/2026

We’re excited to attend and sponsor the Fluorescence Advanced Imaging Research (FLAIR) Workshop! FLAIR brings together the legacy Laboratory for Fluorescence Dynamics (LFD) and Advanced Imaging Methods (AIM) workshops.

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Translucence Biosystems @translucencebio.bsky.social · 05/01/2026

Happy New Year from Translucence Biosystems! We’re excited to continue helping researchers turn intact tissues into actionable insights. Wishing you a year of strong data, smooth experiments, and big breakthroughs.

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Translucence Biosystems @translucencebio.bsky.social · 22/12/2025

Happy Holidays from Translucence Biosystems!

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Translucence Biosystems @translucencebio.bsky.social · 27/11/2025

Happy Thanksgiving! We are thankful for all of our amazing clients, colleagues, and collaborators! Wishing everyone a safe and happy holiday. P.S It's a great time of year to try out the new Translucence Biosystems Turkey Tissue Clearing Protocol 😉

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Translucence Biosystems @translucencebio.bsky.social · 25/11/2025

We had a great time at the Society for Neuroscience (SfN) Annual Meeting in San Diego last week! It was great connecting with friends and partners in the neuroscience community.

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Translucence Biosystems @translucencebio.bsky.social · 17/11/2025

Day 3 of #Neuroscience2025! Join us for our final poster highlighting collaborative work with Innopsys on “High Throughput Immunohistochemistry Imaging and Quantification Using PMT-Generated Images and Cloud-Based ML-Powered Software” (PSTR198.22) from 8 AM - 12 PM.

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Translucence Biosystems @translucencebio.bsky.social · 16/11/2025

We're presenting three posters today from 1-5 PM covering brain-wide quantification of AD pathology (PSTR111.19), tools for mapping neuronal activity with Npas4 and cFos (PSTR143.04), and brain-wide quantification of antibody therapeutics (PSTR111.18), highlighting our collaborative work with Roche.

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Translucence Biosystems @translucencebio.bsky.social · 16/11/2025

Booths open today! Find us at Booth #3224 during #SfN25 from Nov. 15-19, where we'll be sharing our latest advances in tissue clearing, light sheet imaging, and 3D quantification. We're also presenting posters throughout the conference. Stay tuned for poster presentation details!

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Translucence Biosystems @translucencebio.bsky.social · 15/11/2025

Today we will be presenting our first poster (PSTR049.03), where we will highlight tools we've developed to streamline the analysis of large, terabyte-scale light sheet datasets.

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Translucence Biosystems @translucencebio.bsky.social · 15/11/2025

If you have been following along, you will know that we are sharing multiple posters at the Society for Neuroscience (SfN) Annual Meeting in San Diego, California!

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Translucence Biosystems @translucencebio.bsky.social · 13/11/2025

We are excited to announce another poster that we have worked on in collaboration with Innopsys.

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Translucence Biosystems @translucencebio.bsky.social · 11/11/2025

We’re excited to announce another poster that we will be presenting at #SfN2025!

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Translucence Biosystems @translucencebio.bsky.social · 07/11/2025

Thank you for joining us at our recent Lunch and Learn, hosted in collaboration with the Innovation Core at the Weill Institute for Neurosciences at the University of California, San Francisco.

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Translucence Biosystems @translucencebio.bsky.social · 04/11/2025

Happening tomorrow! Join us for a Lunch and Learn event in collaboration with the Innovation Core at the Weill Institute for Neurosciences at UC San Francisco.

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Translucence Biosystems @translucencebio.bsky.social · 30/10/2025

Time is running out! Grab a spot while you still can! Next week, join us for a Lunch and Learn event in collaboration with the Innovation Core at the Weill Institute for Neurosciences at UC San Francisco, on Wednesday, November 5th!

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Translucence Biosystems @translucencebio.bsky.social · 25/10/2025

Happening in a few weeks! Join us for a Lunch and Learn event in collaboration with the Innovation Core at the Weill Institute for Neurosciences at UC San Francisco on November 5th!

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Translucence Biosystems @translucencebio.bsky.social · 21/10/2025

Recent FDA approvals of antibody therapeutics for Alzheimer's Disease, such as Leqembi and Kinsula, mark an important advancement in CNS drug discovery. (1/5)

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Translucence Biosystems @translucencebio.bsky.social · 16/10/2025

We are excited to announce the first of our posters that we will be presenting at #SfN25 this year! Recent advances in tissue clearing and light sheet microscopy enable unprecedented, brain-wide 3D imaging at cellular resolution. @sfn.org

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