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Topf Lab

@topf-lab.bsky.social
30 followers 14 following 0 posts

Our research focuses on developing integrative structural methods that combine experimental data, bioinformatics, and modelling techniques to elucidate the structures of macromolecular assemblies in viruses and their interactions with host cells.

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Leibniz-Institut für Virologie (LIV) @leibnizliv.bsky.social · 21/09/2026
🆕Publication alert! New tool for the analysis of nucleic acid-containing complexes available. The work has recently been published in the (doi/10.34133/csbj.0202). ProNA3D is available as a ChimeraX plugin and as a command-line tool. 🔗https://leibniz-liv.pulse.ly/gux95vvuqv
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Reposted by Topf Lab
Leibniz-Institut für Virologie (LIV) @leibnizliv.bsky.social · 12/03/2026
We're delighted that Prof. Maya Topf (LIV) is joining as fellow of the new #MaxPlanckSchool of Biomedical Artificial Intelligence. The school will connect biomedicine and AI & bring together expertise from 32 fellows across 24 institutions. 👉 maxplanckschools.pulse.ly/vdicv8igar
maxplanckschools.pulse.ly
Max Plank School of Biomedical Artificial Intelligence
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Leibniz-Institut für Virologie (LIV) @leibnizliv.bsky.social · 02/03/2026
TLR8 helps the body detect viral genetic material — but what happens when it’s mutated? A new study in @insight.jci.org from scientists from @leibnizliv.bsky.social, DZKJ and collaborators combines computational modeling and functional experiments to find out: insight.jci.org/articles/vie...
Infografik: A mutated TLR8 gets degraded faster however forms a more stable TLR8 homodimer that leads to increased activation and inflammatory signals.
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Centre for Structural Systems Biology CSSB @cssbhamburg.bsky.social · 11/02/2026
🎉 Happy International Day of Women and Girls in Science 🔬 Some of our group leaders shared insights into what they love most about their jobs in science. ❤️ CSSB supports women and girls in science through initiatives like Girls‘ and Boys‘ Day. #WomenInScience @landaulabcssb.bsky.social
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Leibniz-Institut für Virologie (LIV) @leibnizliv.bsky.social · 05/12/2025
Congrats to Thomas Mulvaney from the @topf-lab.bsky.social for his Nomination for the Leibniz Association’s Dissertation Award — a great recognition of his innovative work on integrative modeling of proteins and nucleic acids. #ResearchExcellence @leibnizliv.bsky.social @cssbhamburg.bsky.social
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Centre for Structural Systems Biology CSSB @cssbhamburg.bsky.social · 25/02/2025
Check out this video summary of the first day of our upcoming symposium "Mechanisms of Infection - from structure to translation." Register by April 8: t1p.de/gztmj @bosse-lab.bsky.social, @carobarisch.bsky.social, @jankosinski.bsky.social, @meytallandau.bsky.social @topf-lab.bsky.social
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