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Tomos Oliver Prys-Jones

@top-j.bsky.social
293 followers 414 following 1 posts

Research Software Engineer for the TB Modelling Group at the London School of Hygiene & Tropical Medicine. Peirianydd Meddalwedd Ynchwil i'r Grwp Modelu TB yn LSHTM

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Reposted by Tomos Oliver Prys-Jones
LSHTM TB Modelling Group @lshtm-tbmod.bsky.social · 23/06/2026
New preprint suggests that combining clinic and community-based approaches is key to maximising the cost-effectiveness of #tuberculosis active case finding in South Africa 🇿🇦 Read more 👉 www.medrxiv.org/content/10.6...
medrxiv.org
Projected population level impact and cost-effectiveness of clinic and community-based tuberculosis screening approaches
The South Africa National Department of Health have set ambitious targets to scale up TB testing, focusing primarily on clinic attendees. In the context of declining funding for TB care and prevention...
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Reposted by Tomos Oliver Prys-Jones
Rebecca Clark @raclark18.bsky.social · 24/02/2026
Our recent modelling study found that the estimated impact of new TB vaccines depends on the efficacy to prevent infectious asymptomatic TB. Read more in our paper out now in @plosmedicine.org! journals.plos.org/plosmedicine...
journals.plos.org
Estimating the population impact of new tuberculosis vaccines depending on efficacy against infectious asymptomatic tuberculosis: A modelling study
Hira Tanvir and colleagues estimate the potential impact of new tuberculosis vaccines under three scenarios of efficacy and conclude that to achieve the greatest impact, vaccines must prevent asymptom...
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Reposted by Tomos Oliver Prys-Jones
PLOS Medicine @plosmedicine.org · 24/02/2026
In this modeling study, Allison Portnoy and colleagues investigate the potential impact of reduced international donor funding on the household economic burden of tuberculosis in low- and middle-income countries 🧪 #MedSky #TB plos.io/4ryyBFX
plos.io
The potential impact of reduced international donor funding on the household economic burden of tuberculosis in low- and middle-income countries: A modeling study
In a modelling study, Allison Portnoy and colleagues investigate the potential impact of reduced international donor funding on the household economic burden of Tuberculosis in low- and middle-income ...
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Reposted by Tomos Oliver Prys-Jones
Katherine Horton @kchorton.bsky.social · 27/08/2025
Community screening for #tuberculosis could extend the reach of #TB services, but evidence on its effectiveness is limited. In our latest preprint, we examine the epidemiological impact of trade-offs in diagnostic algorithm, population coverage, and duration of screening. 1/n bit.ly/3UK7pFD
medrxiv.org
Exploring trade-offs in diagnostic algorithm, population coverage, and duration of community screening for tuberculosis
Background Current tuberculosis (TB) prevention and care strategies have failed to reduce disease burden at the pace required to meet global targets. Community screening may enable more rapid declines...
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Reposted by Tomos Oliver Prys-Jones
Katherine Horton @kchorton.bsky.social · 04/07/2025
In our latest personal view in @lancetrespirmed.bsky.social, we argue for the inclusion asymptomatic #tuberculosis in vaccine trial endpoints to potentially reduce the size, length, and cost of trials. doi.org/10.1016/S221... @lshtm-tbmod.bsky.social @tb-lshtm.bsky.social
Figure 1. Estimated number of trial endpoints in the control group of a prevention-of-disease vaccine trial in a high disease-burden setting showing number of endpoints on the y-axis and time in months on the x-axis. For bacteriologically confirmed symptomatic tuberculosis disease endpoints only, we estimate 69 endpoints, and for combined bacteriologically confirmed asymptomatic and symptomatic tuberculosis disease endpoints, we estimate 151 endpoints. Scenario assumes symptomatic disease incidence before trial screening of 300/100 000 per year and following 10 000 individuals over 3 years. Prevalent symptomatic and asymptomatic tuberculosis disease are screened out in month 0 and are not trial endpoints. Active screening occurs every 6 months for both scenarios and participants self-presenting with symptoms suggestive of tuberculosis disease would also be investigated.
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Reposted by Tomos Oliver Prys-Jones
London School of Hygiene & Tropical Medicine @lshtm.bsky.social · 20/06/2025
LSHTM's Director writes to UK Government about #Gaza public health catastrophe Professor Liam Smeeth's letter to the Prime Minister & Foreign Secretary urges action to prevent a greater #PublicHealth disaster: 👉 www.lshtm.ac.uk/newsevents/n...
Palestinians fleeing northern Gaza on 9 November 2023 amid Israel's bombardment and siege of the enclave, and intense fighting between the Israeli military and Hamas fighters in the north. Credit: Mohammed Zaanoun/TNH
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Tomos Oliver Prys-Jones @top-j.bsky.social · 18/11/2024
A new beginning #goodbyeX #Bali #MonkeyBusiness
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Reposted by Tomos Oliver Prys-Jones
Kate LeGrand @lekate.bsky.social · 17/11/2024
Reflecting on this year’s #TB #UnionConf2024 and am so inspired by the brilliant minds and groundbreaking research being done to combat this global health threat. Special shoutout to the TB Modelling Group @lshtm.bsky.social 🫁
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