iiinova — where your digital self keeps evolving

Reposted by Tonya Zeczycki

PastelBio @pastelbio.bsky.social · 19/03/2025

Kingfisher: An open‐sourced web‐based platform for the analysis of hydrogen exchange mass spectrometry data onlinelibrary.wiley.... --- #proteomics #prot-paper

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Raul Pacheco-Vega @raulpachecovega.bsky.social · 14/03/2025

“You don't start out writing good stuff. You start out writing crap and thinking it's good stuff, and then gradually you get better at it. That's why I say one of the most valuable traits is persistence.” ― Octavia E. Butler #WritingSky #AcademicSky

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US HUPO @us-hupo.org · 08/03/2025

Celebrate International Women's Day by reading the Special Issue of the Journal of Proteome Research, highlighting the essential contributions women scientists have made—and continue to make—in the fields of Proteomics and Metabolomics. ow.ly/eBcV50TWOpV #InternationalWomensDay 🧪

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Jeremy Koster @jeremykoster.bsky.social · 19/02/2025

Upon learning that yesterday would be my last day as a program officer at the National Science Foundation, I shared this parting message with my colleagues. The next few months will be frenetic and stressful for them. Here are some things that you can do to help them with the mission ahead. (1)

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Martin Pacesa @martinpacesa.bsky.social · 01/02/2024

Absolutely captivating article from @fraserlab.bsky.social and Mark Murcko! Very down to earth discussion on what protein "structures" really are www.cell.com/cell/fulltex...

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Nicholas Fitzkee @fitzkeelab.bsky.social · 22/01/2024

Radha follows up her work with a publication in Langmuir. She used NMR hydrogen exchange and methylation mass spec to probe the structure of a small protein binding to a polystyrene nanoparticle. She finds evidence consistent with the adsorbotope model. doi.org/10.1021/acs....

Scheme indicating the use of hydrogen-deuterium exchange and lysine methylation to probe protein structure on a polystyrene nanoparticle.

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Natalie Turner @natalieturnerau.bsky.social · 18/01/2024

Here’s a good one for TeamMassSpec (I hope!)- I’m working on a small project which involves enrichment and MRM of circulating neuropeptides (from blood plasma). Most are hydrophilic peptides (< 3 kDa), 1 is amphipathic (~60 kDa).

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Matt Padula @mattpadula.bsky.social · 08/01/2024

Anyone with experience of converting Waters .raw files into mzML (or something) that can be searched with Fragpipe and other software? MS Convert settings that work would be very helpful. #MassSOS

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Castañeda Lab at SU @castanedalab.bsky.social · 28/12/2023

Pls reskeet: We're accepting PhD apps to Syracuse University Biology! (Priority deadline of 1/4/24) Join a vibrant department: we are also recruiting three new faculty in epigenetics and neuroscience! Labs actively recruiting grad students are here: artsandsciences.syracuse.edu/biology/grad...

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Tonya Zeczycki @tnzeczycki.bsky.social · 21/12/2023

#massspecsos Best way/software for peptide mapping from limited proteolysis or full proteolysis experiments for a single, purified recombinant protein? Something that I can use/search against the Fasta for so the search would be our protein and contaminants with Thermo data.

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Ben Neely @benneely.com · 01/12/2023

A new season of #TheProteomicsShow with me and @proteomicsnews.bsky.social?!!! Find it wherever you podcast and expect a weekly-ish release schedule to bath your ears in proteomic goodness.

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Castañeda Lab at SU @castanedalab.bsky.social · 22/11/2023

Learning my way around Bluesky; hoping to re-establish the many awesome scientific connections from X! We are a molecular biophysics lab also doing cell biology to better understand protein quality control mechanisms in ALS and other neurodegenerative disorders; keen on IDPs, condensates, and NMR!

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PastelBio @pastelbio.bsky.social · 23/11/2023

A Review of Fifteen Years Developing Computational Tools to Study Protein Aggregation www.mdpi.com/2673-41... --- #proteomics #prot-paper

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Reposted by Tonya Zeczycki

Ben Neely @benneely.com · 16/11/2023

To all you #TeamMassSpec and proteomics tweeps who came over, or maybe came over and left, read this blog post: federation is real.

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Ben Neely @benneely.com · 15/11/2023

Wait, The Proteomics Show is one years old today?!!! 7300 listens later and no one has told us to stop, but @proteomicsnews.bsky.social said that would accomplish the opposite anyways, so 🤷‍♂️. Glad people are liking it, we definitely are enjoying doing it. So thanks!

anchor.fm

The Proteomics Show • A podcast on Spotify for Podcasters

Ben Orsburn and Ben Neely co-host a podcast series in a “fireside chat” format with prestigious proteomics researchers. The guests are great, the hosts are questionable.

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Tonya Zeczycki @tnzeczycki.bsky.social · 15/11/2023

Okay my MS peeps- I feel like I am going crazy. I *thought* I read there is a way to calculate a "threshold"/limits for significant fold-changes in a data set based on CV/confidence intervals or something. Arbitrarily going with 2-fold change in abundances as sig always makes me uncomfortable.

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Ben Neely @benneely.com · 06/11/2023

Can you believe it’s time for the Proteomics Old-Time Radio Hour again?! This Wednesday at 10am Pacific/1pm eastern with me, @leannewg.bsky.social, @ucdproteomics.bsky.social and you! Join on clubhouse and bring your friends/questions/topics/secrets.

clubhouse.com

Proteomics Old-Time Radio Hour - Clubhouse

Huuuge group voice notes with all of your friends

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Tonya Zeczycki @tnzeczycki.bsky.social · 05/11/2023

Conversation in my house tonight: Me: Really? You fell asleep at 2 am? When I came to bed at midnight you were snoring. Him (slightly insulted): I don't snore. I "breathe agressively". Me:🤨 Him:😁 Me: You snore.

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Roland Dunbrack 🏳️‍🌈 @rolanddunbrack.bsky.social · 01/11/2023

@rcsbpdb.bsky.social has joined Bluesky! Please follow them and post to them. Let's form a strong structural biology community on this site as the bird site continues to descend into...

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Manjari Narayan | @Neurostats @neurostats.org · 25/10/2023

The mismeasurement of synergistic effects / non-additive interactions seems to happen regularly in some many fields. "Moreover, additive compound pairs with distinct growth/death effects can appear synergistic when only assessed by viability." www.nature.com/articles/s41... ⚕️🤖🧪📈🖥️

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 22/10/2023

They ultimately extended their work to cryo-EM analysis of the complex--WOW!! It confirmed and extended things hypothesized in the other paper 15/n

Model in which dimerized DONSON assembled the complex

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Tonya Zeczycki @tnzeczycki.bsky.social · 10/10/2023

Playing the "how long do we *really* have before we need to submit the poster for printing vs. How much sleep do I *really* need vs. How anxious will I be *not* having said poster printed two days before leaving for the conference" game...it is a dangerous one my friends. Dangerous. #acedemicsky

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Tonya Zeczycki @tnzeczycki.bsky.social · 07/10/2023

Shameless self promotion...but really. Go listen to the rest of these episodes. Because @neely.bsky.social and @proteomicsnews.bsky.social do a kick ass job of chatting with whoever they have on (like actual mass spectrometrists....)

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Tonya Zeczycki @tnzeczycki.bsky.social · 30/09/2023

I take apart high-precision instruments that are worth hundreds of thosands of dollars every day. Yet today, I am filled with panic as I attempt to replace my kitchen faucet. Wish me luck my friends.

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Reposted by Tonya Zeczycki

Ben Garcia @garcialabms.bsky.social · 21/09/2023

#TeamMassSpec roll call. Who’s on this platform?

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Tonya Zeczycki @tnzeczycki.bsky.social · 10/09/2023

Slowly making the transition. Missing all my academic and mass spec chats on the "other" site.....

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