Cell Death & Differentiation - Folliculin depletion results in liver cell damage and cholangiocarcinoma through MiT/TFE activation

AAV-intein-based gene therapy for Stargardt disease proves to be safe and efficacious in large animal models.

D1 receptor agonists bidirectionally regulate working memory capacity (WMC). Here, the authors show that low doses enhance WMC by activating cAMP/PKA in the striatum, whereas high doses impair it via ...

Mathematical modelling and real-time microfluidics-based measurements of nuclear shuttling dynamics of the transcription factor EB (TFEB) demonstrate its biphasic nature in response to nutrient depriv...