The 26S proteasome is essential for proteostasis and constitutes one of the most conserved molecular machineries in eukaryotes. Its homeostasis is maintained by a mechanistically conserved feedback lo...

The 26S proteasome is essential for proteostasis and constitutes one of the most conserved molecular machineries in eukaryotes. Its homeostasis is maintained by a mechanistically conserved feedback lo...

Effective plant immunity requires precise spatial coordination of immune responses across cell-types to restrict pathogens while preventing tissue damage, yet the intracellular pathways that organize ...

Biomolecular condensates formed through phase separation have emerged as a central principle of cellular organization, enabling the dynamic regulation of gene expression, signaling, metabolism, and st...

Here, Schwarze et al. reveal how plant cells match protein quality control to changing rates of protein production through a functional link between TOR kinase signalling and NOT4 E3 ubiquitin ligases

Bacterial pathogens hijack P-body condensates to suppress host translation and dampen plant immunity.

Langin et al. find that ER-associated sorting (ERAS) directs NAC53/78 turnover and activation to couple proteasome induction with repression of photosynthesis genes, linking proteostasis to energy met...

Effective plant immunity requires precise spatial coordination of immune responses across cell-types to restrict pathogens while preventing tissue damage, yet the intracellular pathways that organize ...

More than 15 years ago, during my PhD, we stumbled upon something unexpected. In a yeast two-hybrid screen, bacterial effector proteins from Xanthomonas and Pseudomonas interacted with a subunit of…

When under stress, plants cut back on energy production to focus on breaking down damaged proteins.

Unter Stressbedingungen fahren Pflanzen die Energiegewinnung zurück, um die Priorität zunächst auf den Abbau beschädigter Proteine zu setzen.

Langin et al. find that ER-associated sorting (ERAS) directs NAC53/78 turnover and activation to couple proteasome induction with repression of photosynthesis genes, linking proteostasis to energy metabolism during stress.

Langin et al. find that ER-associated sorting (ERAS) directs NAC53/78 turnover and activation to couple proteasome induction with repression of photosynthesis genes, linking proteostasis to energy met...

Everything started maybe 9 years ago, during my postdoc in Sweden. My colleague and friend Anders Hafrén, now also a group leader working on P-bodies and stress granules during viral infection, had…

Bacteria deactivate the protein synthesis of host cells to hamper immune reactions. This insight could aid in the development of more resistant plants.

Bakterien schalten die Proteinsynthese von Wirtszellen aus, um Immunreaktionen abzuschwächen. Diese Erkenntnis könnte helfen, resistentere Pflanzen zu entwickeln.

To prevent frequent outbreak of diseases, plants have acquired a complex and multi-layered immune system. Cell surface immune receptors recognize conserved pathogen-associated molecular patterns (P…

To prevent frequent outbreak of diseases, plants have acquired a complex and multi-layered immune system. Cell surface immune receptors recognize conserved pathogen-associated molecular patterns (P…