Integrated pharmacological, biochemical, biophysical and structural analyses of small-molecule β-arrestin inhibitors show how they block β-arrestin engagement with activated GPCRs, revealing their mec...

Researchers say they have their reasons for avoiding AI tools — and they’re sick of arguing about it.

Thirteen of the agency’s advisory councils, which must review grant applications before funding is awarded, are on track to have no voting members.

The human sigma-2 receptor/transmembrane protein 97 (σ2R/TMEM97) has been identified as a promising target to modulate neuronal excitability in chronic pain and address the unmet need for nonopioid th...

The Department of Biology in the College of Arts and Sciences at the University of Kentucky in Lexington, KY seeks to fill a tenure-eligible faculty position at the Assistant or Associate Professor le...

ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on

U.S. Rep Thomas Massie (R-KY) declared Saturday evening that his party's leader, the president of the United States, made an unconstitutional move.Trump over the weekend announced his administration had dropped a "full payload of bombs" on Iran."We have completed our very successful attack on the th...

Some cuts have been starkly visible, but the country’s medical grant-making machinery has also radically transformed outside the public eye.

Trump’s national security adviser is trying to manage his way out of a crisis. But new revelations about his team’s operational security are piling up in the inbox.

Rationale and Objective: The pain–depression dyad is highly prevalent and has reciprocal psychological and behavioral effects, leading to poor quality of life, increased disability, and challenging t...

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By blocking announcements in the Federal Register, the administration is keeping experts from meeting to evaluate funding proposals.

At an emotional meeting, foundation officials announced layoffs for about 10 percent of their workforce and warned of more firings to come.

Marine cyanobacteria have gained momentum in recent years as a source of novel bioactive small molecules. This paper describes the structure elucidation and pharmacological evaluation of two new (vera...

Yes, every billionaire really is a policy failure.