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thecleverslab.bsky.social

@thecleverslab.bsky.social
308 followers 4 following 12 posts
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thecleverslab.bsky.social @thecleverslab.bsky.social · 28/09/2026
Using snake airway organoids, we modelled reptile virus infection in vitro. With a new Python Regius reference genome, we show that our organoids contain multiple cell types, could mount an immune response and respond to antivirals. Work from @samwillemsen.bsky.social www.nature.com/articles/s41...
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thecleverslab.bsky.social @thecleverslab.bsky.social · 05/09/2025
4/4 This work was a true team effort between @amolf-nl.bsky.social, IHB Basel, and the @Hubrechtinstitute.bsky.social — led by @danielkrueger.bsky.social and Kasper Spoelstra. Huge thanks to all collaborators for making it possible.
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thecleverslab.bsky.social @thecleverslab.bsky.social · 05/09/2025
3/4 This reveals a safeguard mechanism: epithelial cells constantly test each other’s mechanical strength. Too little (or too much) force destabilizes the barrier, linking extrusion to diseases like tufting enteropathy. Gut renewal is an active, force-regulated process.
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thecleverslab.bsky.social @thecleverslab.bsky.social · 05/09/2025
2/4 Using live imaging, CRISPR myosin reporters, organoid villus substrates & optogenetics, we found that myosin-driven tissue tension—not compression—controls extrusion. Cells with reduced contractility are preferentially removed.
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thecleverslab.bsky.social @thecleverslab.bsky.social · 12/05/2025
Our PhD student @samwillemsen.bsky.social presented our work on thymus organoids at this year’s Global Thymus Network meeting, ThymUS 2025. #ThymUS2025 #Organoids #Thymus
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thecleverslab.bsky.social @thecleverslab.bsky.social · 03/04/2025
The Clevers lab is in Spain! Our postdocs Hanxiao, @sarinashabso.bsky.social, @amandaanderssonr.bsky.social and a PhD student @katarinabalazova.bsky.social are taking part in an @embo.org Workshop on Liver and Pancreas in Metabolic Diseases in Girona 🌞 #embo #liver #pancreas #girona
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thecleverslab.bsky.social @thecleverslab.bsky.social · 03/12/2024
📢New human fetal pancreatic organoid model generates all three key cell types of the pancreas. New paper in @cellpress.bsky.social by @amandaanderssonr.bsky.social , @hansclevers.bsky.social and collaborators. See the article here: www.sciencedirect.com/science/arti...
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